PDB 1ksn

PDB Information

PDB1KSN
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Optimization of the beta-aminoester class of factor Xa inhibitors. Part 2: Identification of FXV673 as a potent and selective inhibitor with excellent In vivo anticoagulant activity.
Guertin, K.R., Gardner, C.J., Klein, S.I., Zulli, A.L., Czekaj, M., Gong, Y., Spada, A.P., Cheney, D.L., Maignan, S., Guilloteau, J.P., Brown, K.D., Colussi, D.J., Chu, V., Heran, C.L., Morgan, S.R., Bentley, R.G., Dunwiddie, C.T., Leadley, R.J., Pauls, H.W.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2002-01-14
Resolution2.100
CATH Insert Date05 Mar, 2006

PDB Images (6)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (3)

Domain ID Date inserted into CATH Superfamily CATH Status
1ksnA01 05 Mar, 2006 2.40.10.10 Assigned
1ksnA02 05 Mar, 2006 2.40.10.10 Assigned
1ksnB00 05 Mar, 2006 2.10.25.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
P00742 FA10_HUMAN Homo sapiens Coagulation factor X
P00742 FA10_HUMAN Homo sapiens Coagulation factor X
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