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PDB 1hvy

PDB Information

PDB1HVY
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHomo sapiens
Primary Citation
Human thymidylate synthase is in the closed conformation when complexed with dUMP and raltitrexed, an antifolate drug
Phan, J., Koli, S., Minor, W., Dunlap, R.B., Berger, S.H., Lebioda, L.
Biochemistry
HeaderTransferase
Released2001-01-08
Resolution1.900
CATH Insert Date05 Mar, 2006

PDB Images (9)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped

CATH Domains (4)

Domain ID Date inserted into CATH Superfamily CATH Status
1hvyA00 05 Mar, 2006 3.30.572.10 Assigned
1hvyB00 05 Mar, 2006 3.30.572.10 Assigned
1hvyC00 05 Mar, 2006 3.30.572.10 Assigned
1hvyD00 05 Mar, 2006 3.30.572.10 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
P04818 TYSY_HUMAN Homo sapiens Thymidylate synthase
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