PDB 1hv7

PDB Information

PDB1HV7
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
The discovery of a potent, intracellular, orally bioavailable, long duration inhibitor of human neutrophil elastase--GW311616A a development candidate
Macdonald, S.J., Dowle, M.D., Harrison, L.A., Shah, P., Johnson, M.R., Inglis, G.G., Clarke, G.D., Smith, R.A., Humphreys, D., Molloy, C.R., Amour, A., Dixon, M., Murkitt, G., Godward, R.E., Padfield, T., Skarzynski, T., Singh, O.M., Kumar, K.A., Fleetwood, G., Hodgson, S.T., Hardy, G.W., Finch, H.
Bioorg.Med.Chem.Lett.
HeaderHydrolase
Released2001-01-08
Resolution1.700
CATH Insert Date05 Mar, 2006

PDB Images (4)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1hv7A01 05 Mar, 2006 2.40.10.10 Assigned
1hv7A02 05 Mar, 2006 2.40.10.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00772 CELA1_PIG Sus scrofa Chymotrypsin-like elastase family member 1