PDB 1h7x

PDB Information

PDB1H7X
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli DH5[alpha]
Gene SourceSUS SCROFA
Primary Citation
Crystal Structure of Dihydropyrimidine Dehydrogenase, a Major Determinant of the Pharmacokinetics of the Anti-Cancer Drug 5-Fluorouracil
Dobritzsch, D., Schneider, G., Schnackerz, K.D., Lindqvist, Y.
Embo J.
HeaderElectron Transfer
Released2001-01-19
Resolution2.010
CATH Insert Date05 Mar, 2006

PDB Images (25)

PDB Prints

PDB Chains (4)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped
C 05 Mar, 2006 Chopped
D 05 Mar, 2006 Chopped

CATH Domains (20)

Domain ID Date inserted into CATH Superfamily CATH Status
1h7xA01 20 Dec, 2006 3.30.70.20 Assigned
1h7xA02 20 Dec, 2006 1.10.1060.10 Assigned
1h7xA03 20 Dec, 2006 3.50.50.60 Assigned
1h7xA04 20 Dec, 2006 3.50.50.60 Assigned
1h7xA05 20 Dec, 2006 3.20.20.70 Assigned
1h7xB01 20 Dec, 2006 3.30.70.20 Assigned
1h7xB02 20 Dec, 2006 1.10.1060.10 Assigned
1h7xB03 20 Dec, 2006 3.50.50.60 Assigned
1h7xB04 20 Dec, 2006 3.50.50.60 Assigned
1h7xB05 20 Dec, 2006 3.20.20.70 Assigned
1h7xC01 20 Dec, 2006 3.30.70.20 Assigned
1h7xC02 20 Dec, 2006 1.10.1060.10 Assigned
1h7xC03 20 Dec, 2006 3.50.50.60 Assigned
1h7xC04 20 Dec, 2006 3.50.50.60 Assigned
1h7xC05 20 Dec, 2006 3.20.20.70 Assigned
1h7xD01 20 Dec, 2006 3.30.70.20 Assigned
1h7xD02 20 Dec, 2006 1.10.1060.10 Assigned
1h7xD03 20 Dec, 2006 3.50.50.60 Assigned
1h7xD04 20 Dec, 2006 3.50.50.60 Assigned
1h7xD05 20 Dec, 2006 3.20.20.70 Assigned

UniProtKB Entries (4)

Accession Gene ID Taxon Description
Q28943 DPYD_PIG Sus scrofa Dihydropyrimidine dehydrogenase [NADP(+)]
Q28943 DPYD_PIG Sus scrofa Dihydropyrimidine dehydrogenase [NADP(+)]
Q28943 DPYD_PIG Sus scrofa Dihydropyrimidine dehydrogenase [NADP(+)]
Q28943 DPYD_PIG Sus scrofa Dihydropyrimidine dehydrogenase [NADP(+)]