PDB 1gth

PDB Links
Overview

PDB Information

PDB	1GTH
Method	X-RAY DIFFRACTION
Host Organism	Escherichia coli DH5[alpha]
Gene Source	SUS SCROFA
Primary Citation	Crystal structure of the productive ternary complex of dihydropyrimidine dehydrogenase with NADPH and 5-iodouracil. Implications for mechanism of inhibition and electron transfer. Dobritzsch, D., Ricagno, S., Schneider, G., Schnackerz, K.D., Lindqvist, Y. J. Biol. Chem.
Header	Oxidoreductase
Released	2002-01-15
Resolution	2.250
CATH Insert Date	05 Mar, 2006

PDB Images (25)

1gth

PDB 1gth

1gthA

PDB Chain 1gthA

1gthB

PDB Chain 1gthB

1gthC

PDB Chain 1gthC

1gthD

PDB Chain 1gthD

1gthA01

CATH Domain 1gthA01

1gthA02

CATH Domain 1gthA02

1gthA03

CATH Domain 1gthA03

1gthA04

CATH Domain 1gthA04

1gthA05

CATH Domain 1gthA05

1gthB01

CATH Domain 1gthB01

1gthB02

CATH Domain 1gthB02

1gthB03

CATH Domain 1gthB03

1gthB04

CATH Domain 1gthB04

1gthB05

CATH Domain 1gthB05

1gthC01

CATH Domain 1gthC01

1gthC02

CATH Domain 1gthC02

1gthC03

CATH Domain 1gthC03

1gthC04

CATH Domain 1gthC04

1gthC05

CATH Domain 1gthC05

1gthD01

CATH Domain 1gthD01

1gthD02

CATH Domain 1gthD02

1gthD03

CATH Domain 1gthD03

1gthD04

CATH Domain 1gthD04

1gthD05

CATH Domain 1gthD05

PDB Prints

PDB Chains (4)

Chain ID	Date inserted into CATH	CATH Status
A	05 Mar, 2006	Chopped
B	05 Mar, 2006	Chopped
C	05 Mar, 2006	Chopped
D	05 Mar, 2006	Chopped

CATH Domains (20)

Domain ID	Date inserted into CATH	Superfamily	CATH Status
1gthA01	22 Dec, 2006	3.30.70.20	Assigned
1gthA02	22 Dec, 2006	1.10.1060.10	Assigned
1gthA03	22 Dec, 2006	3.50.50.60	Assigned
1gthA04	22 Dec, 2006	3.50.50.60	Assigned
1gthA05	22 Dec, 2006	3.20.20.70	Assigned
1gthB01	22 Dec, 2006	3.30.70.20	Assigned
1gthB02	22 Dec, 2006	1.10.1060.10	Assigned
1gthB03	22 Dec, 2006	3.50.50.60	Assigned
1gthB04	22 Dec, 2006	3.50.50.60	Assigned
1gthB05	22 Dec, 2006	3.20.20.70	Assigned
1gthC01	22 Dec, 2006	3.30.70.20	Assigned
1gthC02	22 Dec, 2006	1.10.1060.10	Assigned
1gthC03	22 Dec, 2006	3.50.50.60	Assigned
1gthC04	22 Dec, 2006	3.50.50.60	Assigned
1gthC05	22 Dec, 2006	3.20.20.70	Assigned
1gthD01	22 Dec, 2006	3.30.70.20	Assigned
1gthD02	22 Dec, 2006	1.10.1060.10	Assigned
1gthD03	22 Dec, 2006	3.50.50.60	Assigned
1gthD04	22 Dec, 2006	3.50.50.60	Assigned
1gthD05	22 Dec, 2006	3.20.20.70	Assigned

UniProtKB Entries (4)

Accession	Gene ID	Taxon	Description
Q28943	DPYD_PIG	Sus scrofa	Dihydropyrimidine dehydrogenase [NADP(+)]
Q28943	DPYD_PIG	Sus scrofa	Dihydropyrimidine dehydrogenase [NADP(+)]
Q28943	DPYD_PIG	Sus scrofa	Dihydropyrimidine dehydrogenase [NADP(+)]
Q28943	DPYD_PIG	Sus scrofa	Dihydropyrimidine dehydrogenase [NADP(+)]

Network disruptions