PDB Information

PDB1GJ4
MethodX-RAY DIFFRACTION
Host Organism
Gene Source
Primary Citation
Engineering inhibitors highly selective for the S1 sites of Ser190 trypsin-like serine protease drug targets.
Katz, B.A., Sprengeler, P.A., Luong, C., Verner, E., Elrod, K., Kirtley, M., Janc, J., Spencer, J.R., Breitenbucher, J.G., Hui, H., McGee, D., Allen, D., Martelli, A., Mackman, R.L.
Chem.Biol.
HeaderHydrolase/Hydrolase Inhibitor
Released2001-04-27
Resolution1.810
CATH Insert Date05 Mar, 2006

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
H 05 Mar, 2006 Chopped
I 05 Mar, 2006 Rejected
L 05 Mar, 2006 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1gj4H01 05 Mar, 2006 2.40.10.10 Assigned
1gj4H02 05 Mar, 2006 2.40.10.10 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P00734 THRB_HUMAN Homo sapiens Prothrombin
P28504 HIR2_HIRME Hirudo medicinalis Hirudin-2
P00734 THRB_HUMAN Homo sapiens Prothrombin