PDB Information

PDB1DLS
MethodX-RAY DIFFRACTION
Host Organism
Gene SourceHomo sapiens
Primary Citation
Methotrexate-resistant variants of human dihydrofolate reductase with substitutions of leucine 22. Kinetics, crystallography, and potential as selectable markers.
Lewis, W.S., Cody, V., Galitsky, N., Luft, J.R., Pangborn, W., Chunduru, S.K., Spencer, H.T., Appleman, J.R., Blakley, R.L.
J.Biol.Chem.
HeaderOxido-Reductase
Released1995-01-25
Resolution2.300
CATH Insert Date05 Mar, 2006

PDB Images (3)

PDB Prints

PDB Chains (1)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped

CATH Domains (1)

Domain ID Date inserted into CATH Superfamily CATH Status
1dlsA00 05 Mar, 2006 3.40.430.10 Assigned

UniProtKB Entries (1)

Accession Gene ID Taxon Description
P00374 DYR_HUMAN Homo sapiens Dihydrofolate reductase