PDB Information

Host Organism
Gene SourceHomo sapiens
Primary Citation
The crystal structure of human alpha-thrombin complexed with LY178550, a nonpeptidyl, active site-directed inhibitor.
Chirgadze, N.Y., Sall, D.J., Klimkowski, V.J., Clawson, D.K., Briggs, S.L., Hermann, R., Smith, G.F., Gifford-Moore, D.S., Wery, J.P.
Protein Sci.
HeaderHydrolase/Hydrolase Inhibitor
CATH Insert Date05 Mar, 2006

PDB Images (6)

PDB Prints

PDB Chains (3)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Rejected
B 05 Mar, 2006 Chopped
H 05 Mar, 2006 Rejected

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1d4pB01 05 Mar, 2006 Assigned
1d4pB02 05 Mar, 2006 Assigned

UniProtKB Entries (3)

Accession Gene ID Taxon Description
P00734 THRB_HUMAN Homo sapiens Prothrombin
P01050 HIRV1_HIRME Hirudo medicinalis Hirudin variant-1
P00734 THRB_HUMAN Homo sapiens Prothrombin