PDB 1c70

PDB Information

PDB1C70
MethodX-RAY DIFFRACTION
Host OrganismEscherichia coli
Gene SourceHuman immunodeficiency virus 1
Primary Citation
An alternate binding site for the P1-P3 group of a class of potent HIV-1 protease inhibitors as a result of concerted structural change in the 80s loop of the protease.
Munshi, S., Chen, Z., Yan, Y., Li, Y., Olsen, D.B., Schock, H.B., Galvin, B.B., Dorsey, B., Kuo, L.C.
Acta Crystallogr.,Sect.D
HeaderHydrolase
Released1999-12-29
Resolution2.500
CATH Insert Date05 Mar, 2006

PDB Images (5)

PDB Prints

PDB Chains (2)

Chain ID Date inserted into CATH CATH Status
A 05 Mar, 2006 Chopped
B 05 Mar, 2006 Chopped

CATH Domains (2)

Domain ID Date inserted into CATH Superfamily CATH Status
1c70A00 05 Mar, 2006 2.40.70.10 Assigned
1c70B00 05 Mar, 2006 2.40.70.10 Assigned

UniProtKB Entries (2)

Accession Gene ID Taxon Description
O92103 O92103_9HIV1 Human immunodeficiency virus 1 Protease
O92103 O92103_9HIV1 Human immunodeficiency virus 1 Protease