CATH Domain: 2pjuC01

2pjuC01

PDB 2pju, Chain C, Domain 1

CATH Code	Level Description	Links
3	Alpha Beta
3.40	3-Layer(aba) Sandwich
3.40.50	Rossmann fold
3.40.50.2300		Gene3D
3.40.50.2300.100
3.40.50.2300.100.1
3.40.50.2300.100.1.1
3.40.50.2300.100.1.1.1
3.40.50.2300.100.1.1.1.1

Structure
Sequence
History

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Segment boundaries for domain 2pjuC01

Domain	Start PDB Residue	Stop PDB Residue
2pjuC01	11	88
2pjuC01	177	198
2pjuC02	89	176

What is a Structural Neighbour?

The term "structural neighbour" is used here to describe two CATH domains that share a degree of structural similarity. The SSAP algorithm is used to calculate this similarity and works by generating a structure-based pairwise alignment of the two domains then scoring this alignment using a RMSD score which has been normalised by the length of the larger domain divided by the number of aligned residues (SIMAX).

Structural Neighbourhood (13 entries)

There are 13 matching structural neighberhood comparisons for CATH ID 3.40.50.2300.100.1.1.1.1 (SIMAX score < 5)

Match	SSAP score	Match Keywords	Match Superfamily	Length	Sequence Id	Overlap	RMSD	SIMAX
1vrvA00	81.66	Phosphotransferase system (PTS)Fructose and mannose metabolismPTS system, mannitol-specific IIC componentPTS system, mannitol-specific IIA component [EC:2.7.1.69]PTS system, mannitol-specific IIB component [EC:2.7.1.69]	3.40.50.10370	96	6	84	2.93	3.49
2kyrA00	80.57	PTS system, fructose-specific IIB-like component [EC:2.7.1.69]Escherichia coli K-12Fructose-like phosphotransferase enzyme IIB component 1	3.40.50.2300	108	8	88	4.39	4.94
3eq2B01	79.81	Pseudomonas aeruginosaProbable two-component response regulator	3.40.50.2300	103	9	73	2.39	3.24
2qzjA00	79.27	Two-component response regulatorClostridium difficile 630	3.40.50.2300	119	8	76	2.51	3.28
2q5cA02	78.06	Clostridium acetobutylicumNtrC family transcriptional regulator (PAS and AAA domains)	3.40.50.10660	89	7	71	2.67	3.76
2pjuA02	77.28	Positive regulation of gene-specific transcriptionPropionate catabolism operon regulatory proteinNegative regulation of gene-specific transcriptionEscherichia coli K-12Specific transcriptional repressor activity	3.40.50.10660	88	12	72	2.93	4.07
1p6qA00	77.14	CheY2Two-component system, chemotaxis family, response regulator CheYBacterial chemotaxisSinorhizobium melilotiTwo-component system	3.40.50.2300	129	11	68	3.37	4.88
3cwcB01	76.85	Glycerate kinase [EC:2.7.1.31]Glycerolipid metabolismSalmonella enterica subsp. enterica serovar TyphimuriumPutative glycerate kinase 2Glycine, serine and threonine metabolism	3.40.50.10350	137	14	65	3.12	4.75
1cvrA01	76.72	Gingipain R [EC:3.4.22.37]Porphyromonas gingivalisGingipain R2	3.40.50.10390	117	6	68	2.72	3.98
1z0sA01	75.73	Archaeoglobus fulgidusProbable inorganic polyphosphate/ATP-NAD kinaseNAD+ kinase [EC:2.7.1.23]Nicotinate and nicotinamide metabolismMetabolic pathways	3.40.50.10330	123	9	66	3.01	4.51
3kuuD00	75.56	Purine metabolismMetabolic pathwaysPhosphoribosylaminoimidazole carboxylase catalytic subunit PurE5-(carboxyamino)imidazole ribonucleotide mutase [EC:5.4.99.18]Yersinia pestis	3.40.50.7700	150	13	63	2.97	4.69
1pzxB01	74.51	Geobacillus stearothermophilusLipid binding protein	3.40.50.10440	122	15	75	3.65	4.84
1g7sA03	74.11	Methanothermobacter thermautotrophicus str. Delta HTranslation initiation factor IF-2 unclassified subunitProbable translation initiation factor IF-2	3.40.50.10050	81	8	71	3.45	4.86

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Domain ATOM Sequence

>pdb|2pjuC01
KPVIWTVSVTRLFELFRDISLEFDHLANITPIQLGFEKAVTYIRKKLANERCDAIIAAGSNGAYLKSRLSVPVILIKPYS
AATVRQAFSDALDMTRMSLR

BLAST against CATH

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Domain COMBS Sequence

>pdb|2pjuC01
MSLAHPPRLNDDKPVIWTVSVTRLFELFRDISLEFDHLANITPIQLGFEKAVTYIRKKLANERCDAIIAAGSNGAYLKSR
LSVPVILIKPYSAATVRQAFSDALDMTRMSLR

BLAST against CATH

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Domain History Events (13)

Domain assigned by auto on 18 Mar 2009 14:28

Assigning to "3.40.50.2300" based on similarity with "2pjuB01"

Flow stage update by auto on 18 Mar 2009 14:23

No in_process hits for Domain "2pjuC01" ready to be processed

Update comment by auto on 18 Mar 2009 14:07

Domain "2pjuC01" hits Domain "2pjuB01" (100% over 99.1071428571429%) which is currently in process