S100 Family: 4.10.1080.10.1.1.1.1

Molscript image for 1ux6A01
Representative domain: 1ux6A01
PDB coordinates for domain 1ux6A01

Classification Lineage (4.10.1080.10.1.1.1.1)

CATH CodeLevel DescriptionLinks
4 Few Secondary Structures
4.10 Irregular
4.10.1080 TSP type-3 repeat
4.10.1080.10 TSP type-3 repeat Gene3D
4.10.1080.10.1
4.10.1080.10.1.1
4.10.1080.10.1.1.1
4.10.1080.10.1.1.1.1

Summary of Non-Redundant Representatives
- - - - - - - - 1

S100 Count Entries in S100 Family 4.10.1080.10.1.1.1.1 (1)

CATH Level CATH code Domain ID Keywords Thumbnail
4.10.1080.10.1.1.1.1.1 1ux6A01 p53 signaling pathway, response to magnesium ion, negative regulation of angiogenesis, eukaryotic cell surface binding, negative regulation of plasminogen activation, response to drug, positive regulation of blood vessel endothelial cell migration, extracellular matrix, anti-apoptosis, positive regulation of protein kinase B signaling cascade, apoptosis, positive regulation of oxygen and reactive oxygen species metabolic process, fibroblast growth factor 2 binding, positive regulation of tumor necrosis factor biosynthetic process, positive regulation of angiogenesis, laminin binding, heparin binding, response to glucose stimulus, peptide cross-linking, activation of MAPK activity, cell cycle arrest, sprouting angiogenesis, transforming growth factor beta binding, collagen V binding, positive regulation of phosphorylation, response to progesterone stimulus, negative regulation of antigen processing and presentation of peptide or polysaccharide antigen via MHC class II, fibrinogen complex, Homo sapiens, cell migration, immune response, Bladder cancer, negative regulation of plasma membrane long-chain fatty acid transport, TGF-beta signaling pathway, positive regulation of translation, proteoglycan binding, negative regulation of endothelial cell proliferation, negative regulation of interleukin-12 production, low-density lipoprotein binding, engulfment of apoptotic cell, negative regulation of blood vessel endothelial cell migration, response to calcium ion, negative regulation of fibrinolysis, induction of apoptosis, negative regulation of focal adhesion assembly, phosphatidylserine binding, Focal adhesion, negative regulation of caspase activity, fibrinogen binding, negative regulation of dendritic cell antigen processing and presentation, external side of plasma membrane, Thrombospondin-1, integrin binding, negative regulation of fibroblast growth factor receptor signaling pathway, positive regulation of macrophage activation, negative regulation of cGMP-mediated signaling, fibronectin binding, positive regulation of transforming growth factor beta receptor signaling pathway, negative regulation of nitric oxide mediated signal transduction, thrombospondin, chronic inflammatory response, ECM-receptor interaction, positive regulation of fibroblast migration Molscript image for 1ux6A01

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
  • Multiple alignments for each functional family
  • Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
  • Detailed functional information on diversity and conservation within Functional families
  • Multi-domain architectures
In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages:
http://gene3d.biochem.ucl.ac.uk/superfamily/?accession=4.10.1080.10.1.1.1.1