S100 Family: 3.90.550.10.4.1.1.1

Representative domain: 1fxoA00

Classification Lineage (3.90.550.10.4.1.1.1)

CATH Code	Level Description	Links
3	Alpha Beta
3.90	Alpha-Beta Complex
3.90.550	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A
3.90.550.10	Spore Coat Polysaccharide Biosynthesis Protein SpsA; Chain A	Gene3D
3.90.550.10.4
3.90.550.10.4.1
3.90.550.10.4.1.1
3.90.550.10.4.1.1.1

Summary of Non-Redundant Representatives


-	-	-	-	-	-	-	-	44

Non-Redundant Representatives (44)
Functional Families
Help

What is a Non-Redundant Representative?

CATH is a tree-like organisation of nodes that begins with the class node (i.e. the first branch-point of the tree) and ends with the domain nodes (i.e. the leaves of the tree). Each node below the class have a parent that they belong to, e.g. the parent of the H level (Homologous superfamily) is the T (Topology). Additionally, each node above the domains have child nodes that belong to them, e.g. the child nodes of a given H (Homologous superfamily) level are the S35 families (domains clustered at > 35% sequence identity).

S100 Count Entries in S100 Family 3.90.550.10.4.1.1.1 (44)

CATH code	Domain ID	Keywords
3.90.550.10.4.1.1.1.1	1fxoA00	Pseudomonas aeruginosa, Metabolic pathways, Polyketide sugar unit biosynthesis, Glucose-1-phosphate thymidylyltransferase., Glucose-1-phosphate thymidylyltransferase, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Streptomycin biosynthesis
3.90.550.10.4.1.1.1.2	1fxoC00	glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Streptomycin biosynthesis, Glucose-1-phosphate thymidylyltransferase, Polyketide sugar unit biosynthesis, Metabolic pathways, Glucose-1-phosphate thymidylyltransferase., Pseudomonas aeruginosa
3.90.550.10.4.1.1.1.3	1fxoD00	Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Glucose-1-phosphate thymidylyltransferase, Glucose-1-phosphate thymidylyltransferase., Metabolic pathways, Polyketide sugar unit biosynthesis, Pseudomonas aeruginosa
3.90.550.10.4.1.1.1.4	1fxoH00	Glucose-1-phosphate thymidylyltransferase., Metabolic pathways, Polyketide sugar unit biosynthesis, Pseudomonas aeruginosa, Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Glucose-1-phosphate thymidylyltransferase
3.90.550.10.4.1.1.1.5	1fxoB00	Glucose-1-phosphate thymidylyltransferase., Metabolic pathways, Polyketide sugar unit biosynthesis, Pseudomonas aeruginosa, Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Glucose-1-phosphate thymidylyltransferase
3.90.550.10.4.1.1.1.6	1fxoE00	Pseudomonas aeruginosa, Metabolic pathways, Polyketide sugar unit biosynthesis, Glucose-1-phosphate thymidylyltransferase., Glucose-1-phosphate thymidylyltransferase, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Streptomycin biosynthesis
3.90.550.10.4.1.1.1.7	1fxoF00	Glucose-1-phosphate thymidylyltransferase, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Streptomycin biosynthesis, Pseudomonas aeruginosa, Polyketide sugar unit biosynthesis, Metabolic pathways, Glucose-1-phosphate thymidylyltransferase.
3.90.550.10.4.1.1.1.8	1fxoG00	Pseudomonas aeruginosa, Glucose-1-phosphate thymidylyltransferase., Metabolic pathways, Polyketide sugar unit biosynthesis, Glucose-1-phosphate thymidylyltransferase, Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
3.90.550.10.4.1.1.1.9	1g1lA00	Pseudomonas aeruginosa, Glucose-1-phosphate thymidylyltransferase., Metabolic pathways, Polyketide sugar unit biosynthesis, Glucose-1-phosphate thymidylyltransferase, Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
3.90.550.10.4.1.1.1.10	1g1lC00	Glucose-1-phosphate thymidylyltransferase., Polyketide sugar unit biosynthesis, Metabolic pathways, Pseudomonas aeruginosa, Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Glucose-1-phosphate thymidylyltransferase
3.90.550.10.4.1.1.1.11	1g1lD00	Pseudomonas aeruginosa, Polyketide sugar unit biosynthesis, Metabolic pathways, Glucose-1-phosphate thymidylyltransferase., Glucose-1-phosphate thymidylyltransferase, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Streptomycin biosynthesis
3.90.550.10.4.1.1.1.12	1g1lE00	Pseudomonas aeruginosa, Polyketide sugar unit biosynthesis, Metabolic pathways, Glucose-1-phosphate thymidylyltransferase., Glucose-1-phosphate thymidylyltransferase, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Streptomycin biosynthesis
3.90.550.10.4.1.1.1.13	1g1lG00	Glucose-1-phosphate thymidylyltransferase, Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Pseudomonas aeruginosa, Glucose-1-phosphate thymidylyltransferase., Metabolic pathways, Polyketide sugar unit biosynthesis
3.90.550.10.4.1.1.1.14	1g1lH00	Pseudomonas aeruginosa, Metabolic pathways, Polyketide sugar unit biosynthesis, Glucose-1-phosphate thymidylyltransferase., Glucose-1-phosphate thymidylyltransferase, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Streptomycin biosynthesis
3.90.550.10.4.1.1.1.15	1g1lB00	glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Streptomycin biosynthesis, Glucose-1-phosphate thymidylyltransferase, Polyketide sugar unit biosynthesis, Metabolic pathways, Glucose-1-phosphate thymidylyltransferase., Pseudomonas aeruginosa
3.90.550.10.4.1.1.1.16	1g1lF00	Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Glucose-1-phosphate thymidylyltransferase, Glucose-1-phosphate thymidylyltransferase., Metabolic pathways, Polyketide sugar unit biosynthesis, Pseudomonas aeruginosa
3.90.550.10.4.1.1.1.17	1g0rA00	Glucose-1-phosphate thymidylyltransferase, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Streptomycin biosynthesis, Pseudomonas aeruginosa, Metabolic pathways, Polyketide sugar unit biosynthesis, Glucose-1-phosphate thymidylyltransferase.
3.90.550.10.4.1.1.1.18	1g0rB00	Polyketide sugar unit biosynthesis, Metabolic pathways, Glucose-1-phosphate thymidylyltransferase., Pseudomonas aeruginosa, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Streptomycin biosynthesis, Glucose-1-phosphate thymidylyltransferase
3.90.550.10.4.1.1.1.19	1g0rC00	glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Streptomycin biosynthesis, Glucose-1-phosphate thymidylyltransferase, Metabolic pathways, Polyketide sugar unit biosynthesis, Glucose-1-phosphate thymidylyltransferase., Pseudomonas aeruginosa
3.90.550.10.4.1.1.1.20	1g0rD00	Glucose-1-phosphate thymidylyltransferase, Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Pseudomonas aeruginosa, Glucose-1-phosphate thymidylyltransferase., Metabolic pathways, Polyketide sugar unit biosynthesis
3.90.550.10.4.1.1.1.21	1g0rE00	Glucose-1-phosphate thymidylyltransferase, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Streptomycin biosynthesis, Pseudomonas aeruginosa, Polyketide sugar unit biosynthesis, Metabolic pathways, Glucose-1-phosphate thymidylyltransferase.
3.90.550.10.4.1.1.1.22	1g0rG00	glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Streptomycin biosynthesis, Glucose-1-phosphate thymidylyltransferase, Metabolic pathways, Polyketide sugar unit biosynthesis, Glucose-1-phosphate thymidylyltransferase., Pseudomonas aeruginosa
3.90.550.10.4.1.1.1.23	1g0rH00	Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Glucose-1-phosphate thymidylyltransferase, Glucose-1-phosphate thymidylyltransferase., Polyketide sugar unit biosynthesis, Metabolic pathways, Pseudomonas aeruginosa
3.90.550.10.4.1.1.1.24	1g0rF00	Glucose-1-phosphate thymidylyltransferase., Polyketide sugar unit biosynthesis, Metabolic pathways, Pseudomonas aeruginosa, Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Glucose-1-phosphate thymidylyltransferase
3.90.550.10.4.1.1.1.25	1fzwA00	Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Glucose-1-phosphate thymidylyltransferase, Glucose-1-phosphate thymidylyltransferase., Polyketide sugar unit biosynthesis, Metabolic pathways, Pseudomonas aeruginosa
3.90.550.10.4.1.1.1.26	1fzwB00	Pseudomonas aeruginosa, Polyketide sugar unit biosynthesis, Metabolic pathways, Glucose-1-phosphate thymidylyltransferase., Glucose-1-phosphate thymidylyltransferase, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Streptomycin biosynthesis
3.90.550.10.4.1.1.1.27	1fzwD00	Polyketide sugar unit biosynthesis, Metabolic pathways, Glucose-1-phosphate thymidylyltransferase., Pseudomonas aeruginosa, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Streptomycin biosynthesis, Glucose-1-phosphate thymidylyltransferase
3.90.550.10.4.1.1.1.28	1fzwE00	Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Glucose-1-phosphate thymidylyltransferase, Glucose-1-phosphate thymidylyltransferase., Metabolic pathways, Polyketide sugar unit biosynthesis, Pseudomonas aeruginosa
3.90.550.10.4.1.1.1.29	1fzwG00	Pseudomonas aeruginosa, Glucose-1-phosphate thymidylyltransferase., Polyketide sugar unit biosynthesis, Metabolic pathways, Glucose-1-phosphate thymidylyltransferase, Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
3.90.550.10.4.1.1.1.30	1fzwH00	Glucose-1-phosphate thymidylyltransferase, Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Pseudomonas aeruginosa, Glucose-1-phosphate thymidylyltransferase., Polyketide sugar unit biosynthesis, Metabolic pathways
3.90.550.10.4.1.1.1.31	1fzwC00	Polyketide sugar unit biosynthesis, Metabolic pathways, Glucose-1-phosphate thymidylyltransferase., Pseudomonas aeruginosa, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Streptomycin biosynthesis, Glucose-1-phosphate thymidylyltransferase
3.90.550.10.4.1.1.1.32	1fzwF00	Glucose-1-phosphate thymidylyltransferase., Metabolic pathways, Polyketide sugar unit biosynthesis, Pseudomonas aeruginosa, Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Glucose-1-phosphate thymidylyltransferase
3.90.550.10.4.1.1.1.33	1g2vA00	Glucose-1-phosphate thymidylyltransferase, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Streptomycin biosynthesis, Pseudomonas aeruginosa, Polyketide sugar unit biosynthesis, Metabolic pathways, Glucose-1-phosphate thymidylyltransferase.
3.90.550.10.4.1.1.1.34	1g2vB00	Polyketide sugar unit biosynthesis, Metabolic pathways, Glucose-1-phosphate thymidylyltransferase., Pseudomonas aeruginosa, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Streptomycin biosynthesis, Glucose-1-phosphate thymidylyltransferase
3.90.550.10.4.1.1.1.35	1g2vC00	Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Glucose-1-phosphate thymidylyltransferase, Glucose-1-phosphate thymidylyltransferase., Metabolic pathways, Polyketide sugar unit biosynthesis, Pseudomonas aeruginosa
3.90.550.10.4.1.1.1.36	1g2vD00	Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Glucose-1-phosphate thymidylyltransferase, Glucose-1-phosphate thymidylyltransferase., Polyketide sugar unit biosynthesis, Metabolic pathways, Pseudomonas aeruginosa
3.90.550.10.4.1.1.1.37	1g2vE00	Glucose-1-phosphate thymidylyltransferase, Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Pseudomonas aeruginosa, Glucose-1-phosphate thymidylyltransferase., Polyketide sugar unit biosynthesis, Metabolic pathways
3.90.550.10.4.1.1.1.38	1g2vF00	Pseudomonas aeruginosa, Polyketide sugar unit biosynthesis, Metabolic pathways, Glucose-1-phosphate thymidylyltransferase., Glucose-1-phosphate thymidylyltransferase, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Streptomycin biosynthesis
3.90.550.10.4.1.1.1.39	1g2vG00	Glucose-1-phosphate thymidylyltransferase., Polyketide sugar unit biosynthesis, Metabolic pathways, Pseudomonas aeruginosa, Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Glucose-1-phosphate thymidylyltransferase
3.90.550.10.4.1.1.1.40	1g2vH00	Pseudomonas aeruginosa, Glucose-1-phosphate thymidylyltransferase., Metabolic pathways, Polyketide sugar unit biosynthesis, Glucose-1-phosphate thymidylyltransferase, Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
3.90.550.10.4.1.1.1.41	1g3lA00	Pseudomonas aeruginosa, Glucose-1-phosphate thymidylyltransferase., Metabolic pathways, Polyketide sugar unit biosynthesis, Glucose-1-phosphate thymidylyltransferase, Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24]
3.90.550.10.4.1.1.1.42	1g3lB00	Streptomycin biosynthesis, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Glucose-1-phosphate thymidylyltransferase, Glucose-1-phosphate thymidylyltransferase., Metabolic pathways, Polyketide sugar unit biosynthesis, Pseudomonas aeruginosa
3.90.550.10.4.1.1.1.43	1g3lC00	Pseudomonas aeruginosa, Metabolic pathways, Polyketide sugar unit biosynthesis, Glucose-1-phosphate thymidylyltransferase., Glucose-1-phosphate thymidylyltransferase, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Streptomycin biosynthesis
3.90.550.10.4.1.1.1.44	1g3lD00	Glucose-1-phosphate thymidylyltransferase, glucose-1-phosphate thymidylyltransferase [EC:2.7.7.24], Streptomycin biosynthesis, Pseudomonas aeruginosa, Metabolic pathways, Polyketide sugar unit biosynthesis, Glucose-1-phosphate thymidylyltransferase.

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:

Multiple alignments for each functional family
Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
Detailed functional information on diversity and conservation within Functional families
Multi-domain architectures

In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages:

http://gene3d.biochem.ucl.ac.uk/superfamily/?accession=3.90.550.10.4.1.1.1

What is a Non-Redundant Representative?

Why can't I have a multiple structural alignment of the whole superfamily?

The simple answer is that some of the larger superfamilies in CATH comprise relatives which are very structurally diverse, having different secondary structure embellishments. Attempting to provide a global alignment of all domains in the superfamily would result in poor quality alignments. As a result, structural alignments in CATH are generated by first clustering together the structures that have at least some recognisable structural similarity using a normalised RMSD score (SIMAX = RMSDxNumber of residues in the largest domain/number of aligned residues) less than a given cutoff.

What is an Close Structural Cluster?

A Close Structural Cluster describes a cluster of two or more CATH domains that have been grouped together due to their close structural similarity (SIMAX score < 5Å where SIMAX = RMSD x Number of residues in the larger domain/number of aligned residues).

What is a Distant Structural Cluster?

A Distant Structural Cluster describes a cluster of two or CATH domains that have been grouped together with a more relaxed structural similarity threshold to investigate more distant evolutionary similarities (SIMAX score < 5Å where SIMAX = RMSD x Number of residues in the larger domain/number of aligned residues).

What is a Structural Neighbour?

The term "structural neighbour" is used here to describe two CATH domains that share a degree of structural similarity. The SSAP algorithm is used to calculate this similarity and works by generating a structure-based pairwise alignment of the two domains then scoring this alignment using a RMSD score which has been normalised by the length of the larger domain divided by the number of aligned residues (SIMAX).

S100 Family: 3.90.550.10.4.1.1.1

Classification Lineage (3.90.550.10.4.1.1.1)

Summary of Non-Redundant Representatives

What is a Non-Redundant Representative?

S100 Count Entries in S100 Family 3.90.550.10.4.1.1.1 (44)

What is a Non-Redundant Representative?

Why can't I have a multiple structural alignment of the whole superfamily?

What is an Close Structural Cluster?

What is a Distant Structural Cluster?

What is a Structural Neighbour?

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