S100 Family: 3.40.50.10190.3.1.1.1

Molscript image for 1t15A01
Representative domain: 1t15A01
PDB coordinates for domain 1t15A01

Classification Lineage (3.40.50.10190.3.1.1.1)

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.40 3-Layer(aba) Sandwich
3.40.50 Rossmann fold
3.40.50.10190 Gene3D
3.40.50.10190.3
3.40.50.10190.3.1
3.40.50.10190.3.1.1
3.40.50.10190.3.1.1.1

Summary of Non-Redundant Representatives
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S100 Count Entries in S100 Family 3.40.50.10190.3.1.1.1 (23)

CATH Level CATH code Domain ID Keywords Thumbnail
3.40.50.10190.3.1.1.1.1 1t15A01 BRCA1-A complex, Ubiquitin mediated proteolysis, G2/M transition DNA damage checkpoint, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, zinc ion binding, positive regulation of protein ubiquitination, regulation of transcription from RNA polymerase III promoter, response to estrogen stimulus, DNA binding, regulation of cell proliferation, negative regulation of transcription, RNA binding, identical protein binding, regulation of transcription from RNA polymerase II promoter, Breast cancer type 1 susceptibility protein, negative regulation of fatty acid biosynthetic process, apoptosis, Acid--D-amino-acid ligases (peptide synthases)., positive regulation of DNA repair, ribonucleoprotein complex, enzyme binding, DNA damage response, signal transduction resulting in induction of apoptosis, postreplication repair, double-strand break repair via homologous recombination, protein ubiquitination, Homo sapiens, response to ionizing radiation, chromosome segregation, BRCA1-BARD1 complex, breast cancer type 1 susceptibility protein Molscript image for 1t15A01
3.40.50.10190.3.1.1.1.2 1t29A01 breast cancer type 1 susceptibility protein, BRCA1-BARD1 complex, Homo sapiens, response to ionizing radiation, chromosome segregation, protein ubiquitination, enzyme binding, double-strand break repair via homologous recombination, DNA damage response, signal transduction resulting in induction of apoptosis, postreplication repair, positive regulation of DNA repair, ribonucleoprotein complex, Acid--D-amino-acid ligases (peptide synthases)., apoptosis, negative regulation of fatty acid biosynthetic process, Breast cancer type 1 susceptibility protein, identical protein binding, regulation of transcription from RNA polymerase II promoter, RNA binding, negative regulation of transcription, regulation of cell proliferation, positive regulation of protein ubiquitination, response to estrogen stimulus, DNA binding, regulation of transcription from RNA polymerase III promoter, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, zinc ion binding, G2/M transition DNA damage checkpoint, BRCA1-A complex, Ubiquitin mediated proteolysis Molscript image for 1t29A01
3.40.50.10190.3.1.1.1.3 1jnxX01 Breast cancer type 1 susceptibility protein, identical protein binding, regulation of transcription from RNA polymerase II promoter, RNA binding, negative regulation of transcription, regulation of cell proliferation, positive regulation of protein ubiquitination, DNA binding, regulation of transcription from RNA polymerase III promoter, response to estrogen stimulus, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, zinc ion binding, G2/M transition DNA damage checkpoint, BRCA1-A complex, Ubiquitin mediated proteolysis, BRCA1-BARD1 complex, breast cancer type 1 susceptibility protein, Homo sapiens, response to ionizing radiation, chromosome segregation, protein ubiquitination, enzyme binding, postreplication repair, DNA damage response, signal transduction resulting in induction of apoptosis, double-strand break repair via homologous recombination, positive regulation of DNA repair, ribonucleoprotein complex, negative regulation of fatty acid biosynthetic process, apoptosis, Acid--D-amino-acid ligases (peptide synthases). Molscript image for 1jnxX01
3.40.50.10190.3.1.1.1.4 1y98A01 G2/M transition DNA damage checkpoint, BRCA1-A complex, Ubiquitin mediated proteolysis, positive regulation of protein ubiquitination, DNA binding, regulation of transcription from RNA polymerase III promoter, response to estrogen stimulus, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, zinc ion binding, RNA binding, negative regulation of transcription, regulation of cell proliferation, Breast cancer type 1 susceptibility protein, identical protein binding, regulation of transcription from RNA polymerase II promoter, Acid--D-amino-acid ligases (peptide synthases)., negative regulation of fatty acid biosynthetic process, apoptosis, enzyme binding, double-strand break repair via homologous recombination, postreplication repair, DNA damage response, signal transduction resulting in induction of apoptosis, positive regulation of DNA repair, ribonucleoprotein complex, protein ubiquitination, breast cancer type 1 susceptibility protein, BRCA1-BARD1 complex, Homo sapiens, response to ionizing radiation, chromosome segregation Molscript image for 1y98A01
3.40.50.10190.3.1.1.1.5 3k0hA01 Breast cancer type 1 susceptibility protein, identical protein binding, regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, RNA binding, regulation of cell proliferation, positive regulation of protein ubiquitination, regulation of transcription from RNA polymerase III promoter, DNA binding, response to estrogen stimulus, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, zinc ion binding, G2/M transition DNA damage checkpoint, BRCA1-A complex, Ubiquitin mediated proteolysis, BRCA1-BARD1 complex, breast cancer type 1 susceptibility protein, Homo sapiens, response to ionizing radiation, chromosome segregation, protein ubiquitination, enzyme binding, postreplication repair, DNA damage response, signal transduction resulting in induction of apoptosis, double-strand break repair via homologous recombination, positive regulation of DNA repair, ribonucleoprotein complex, apoptosis, negative regulation of fatty acid biosynthetic process, Acid--D-amino-acid ligases (peptide synthases). Molscript image for 3k0hA01
3.40.50.10190.3.1.1.1.6 3k0kA01 chromosome segregation, Homo sapiens, response to ionizing radiation, BRCA1-BARD1 complex, breast cancer type 1 susceptibility protein, protein ubiquitination, ribonucleoprotein complex, positive regulation of DNA repair, postreplication repair, DNA damage response, signal transduction resulting in induction of apoptosis, double-strand break repair via homologous recombination, enzyme binding, apoptosis, negative regulation of fatty acid biosynthetic process, Acid--D-amino-acid ligases (peptide synthases)., regulation of transcription from RNA polymerase II promoter, identical protein binding, Breast cancer type 1 susceptibility protein, regulation of cell proliferation, RNA binding, negative regulation of transcription, zinc ion binding, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, response to estrogen stimulus, DNA binding, regulation of transcription from RNA polymerase III promoter, positive regulation of protein ubiquitination, Ubiquitin mediated proteolysis, BRCA1-A complex, G2/M transition DNA damage checkpoint Molscript image for 3k0kA01
3.40.50.10190.3.1.1.1.7 1n5oX01 BRCA1-BARD1 complex, breast cancer type 1 susceptibility protein, Homo sapiens, response to ionizing radiation, chromosome segregation, protein ubiquitination, enzyme binding, DNA damage response, signal transduction resulting in induction of apoptosis, postreplication repair, double-strand break repair via homologous recombination, positive regulation of DNA repair, ribonucleoprotein complex, apoptosis, negative regulation of fatty acid biosynthetic process, Acid--D-amino-acid ligases (peptide synthases)., Breast cancer type 1 susceptibility protein, identical protein binding, regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, RNA binding, regulation of cell proliferation, positive regulation of protein ubiquitination, regulation of transcription from RNA polymerase III promoter, response to estrogen stimulus, DNA binding, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, zinc ion binding, G2/M transition DNA damage checkpoint, BRCA1-A complex, Ubiquitin mediated proteolysis Molscript image for 1n5oX01
3.40.50.10190.3.1.1.1.8 1t2uA01 Breast cancer type 1 susceptibility protein, regulation of transcription from RNA polymerase II promoter, identical protein binding, RNA binding, negative regulation of transcription, regulation of cell proliferation, response to estrogen stimulus, regulation of transcription from RNA polymerase III promoter, DNA binding, positive regulation of protein ubiquitination, zinc ion binding, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, G2/M transition DNA damage checkpoint, Ubiquitin mediated proteolysis, BRCA1-A complex, breast cancer type 1 susceptibility protein, BRCA1-BARD1 complex, chromosome segregation, Homo sapiens, response to ionizing radiation, protein ubiquitination, double-strand break repair via homologous recombination, DNA damage response, signal transduction resulting in induction of apoptosis, postreplication repair, enzyme binding, ribonucleoprotein complex, positive regulation of DNA repair, Acid--D-amino-acid ligases (peptide synthases)., negative regulation of fatty acid biosynthetic process, apoptosis Molscript image for 1t2uA01
3.40.50.10190.3.1.1.1.9 3k15A01 DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, zinc ion binding, positive regulation of protein ubiquitination, DNA binding, response to estrogen stimulus, regulation of transcription from RNA polymerase III promoter, BRCA1-A complex, Ubiquitin mediated proteolysis, G2/M transition DNA damage checkpoint, identical protein binding, regulation of transcription from RNA polymerase II promoter, Breast cancer type 1 susceptibility protein, regulation of cell proliferation, RNA binding, negative regulation of transcription, positive regulation of DNA repair, ribonucleoprotein complex, enzyme binding, double-strand break repair via homologous recombination, postreplication repair, DNA damage response, signal transduction resulting in induction of apoptosis, Acid--D-amino-acid ligases (peptide synthases)., apoptosis, negative regulation of fatty acid biosynthetic process, Homo sapiens, response to ionizing radiation, chromosome segregation, breast cancer type 1 susceptibility protein, BRCA1-BARD1 complex, protein ubiquitination Molscript image for 3k15A01
3.40.50.10190.3.1.1.1.10 3k16A01 negative regulation of fatty acid biosynthetic process, apoptosis, Acid--D-amino-acid ligases (peptide synthases)., DNA damage response, signal transduction resulting in induction of apoptosis, postreplication repair, double-strand break repair via homologous recombination, enzyme binding, ribonucleoprotein complex, positive regulation of DNA repair, protein ubiquitination, BRCA1-BARD1 complex, breast cancer type 1 susceptibility protein, chromosome segregation, Homo sapiens, response to ionizing radiation, G2/M transition DNA damage checkpoint, Ubiquitin mediated proteolysis, BRCA1-A complex, regulation of transcription from RNA polymerase III promoter, DNA binding, response to estrogen stimulus, positive regulation of protein ubiquitination, zinc ion binding, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, negative regulation of transcription, RNA binding, regulation of cell proliferation, Breast cancer type 1 susceptibility protein, regulation of transcription from RNA polymerase II promoter, identical protein binding Molscript image for 3k16A01
3.40.50.10190.3.1.1.1.11 3cojD01 ribonucleoprotein complex, positive regulation of DNA repair, postreplication repair, DNA damage response, signal transduction resulting in induction of apoptosis, double-strand break repair via homologous recombination, enzyme binding, apoptosis, negative regulation of fatty acid biosynthetic process, Acid--D-amino-acid ligases (peptide synthases)., chromosome segregation, Homo sapiens, response to ionizing radiation, BRCA1-BARD1 complex, breast cancer type 1 susceptibility protein, protein ubiquitination, zinc ion binding, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, regulation of transcription from RNA polymerase III promoter, DNA binding, response to estrogen stimulus, positive regulation of protein ubiquitination, Ubiquitin mediated proteolysis, BRCA1-A complex, G2/M transition DNA damage checkpoint, regulation of transcription from RNA polymerase II promoter, identical protein binding, Breast cancer type 1 susceptibility protein, regulation of cell proliferation, RNA binding, negative regulation of transcription Molscript image for 3cojD01
3.40.50.10190.3.1.1.1.12 3cojE01 positive regulation of DNA repair, ribonucleoprotein complex, enzyme binding, double-strand break repair via homologous recombination, postreplication repair, DNA damage response, signal transduction resulting in induction of apoptosis, Acid--D-amino-acid ligases (peptide synthases)., negative regulation of fatty acid biosynthetic process, apoptosis, Homo sapiens, response to ionizing radiation, chromosome segregation, breast cancer type 1 susceptibility protein, BRCA1-BARD1 complex, protein ubiquitination, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, zinc ion binding, positive regulation of protein ubiquitination, regulation of transcription from RNA polymerase III promoter, DNA binding, response to estrogen stimulus, BRCA1-A complex, Ubiquitin mediated proteolysis, G2/M transition DNA damage checkpoint, identical protein binding, regulation of transcription from RNA polymerase II promoter, Breast cancer type 1 susceptibility protein, regulation of cell proliferation, RNA binding, negative regulation of transcription Molscript image for 3cojE01
3.40.50.10190.3.1.1.1.13 3cojF01 protein ubiquitination, breast cancer type 1 susceptibility protein, BRCA1-BARD1 complex, Homo sapiens, response to ionizing radiation, chromosome segregation, Acid--D-amino-acid ligases (peptide synthases)., negative regulation of fatty acid biosynthetic process, apoptosis, enzyme binding, double-strand break repair via homologous recombination, postreplication repair, DNA damage response, signal transduction resulting in induction of apoptosis, positive regulation of DNA repair, ribonucleoprotein complex, negative regulation of transcription, RNA binding, regulation of cell proliferation, Breast cancer type 1 susceptibility protein, identical protein binding, regulation of transcription from RNA polymerase II promoter, G2/M transition DNA damage checkpoint, BRCA1-A complex, Ubiquitin mediated proteolysis, positive regulation of protein ubiquitination, response to estrogen stimulus, regulation of transcription from RNA polymerase III promoter, DNA binding, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, zinc ion binding Molscript image for 3cojF01
3.40.50.10190.3.1.1.1.14 3cojA01 negative regulation of fatty acid biosynthetic process, apoptosis, Acid--D-amino-acid ligases (peptide synthases)., DNA damage response, signal transduction resulting in induction of apoptosis, postreplication repair, double-strand break repair via homologous recombination, enzyme binding, ribonucleoprotein complex, positive regulation of DNA repair, protein ubiquitination, BRCA1-BARD1 complex, breast cancer type 1 susceptibility protein, chromosome segregation, Homo sapiens, response to ionizing radiation, G2/M transition DNA damage checkpoint, Ubiquitin mediated proteolysis, BRCA1-A complex, regulation of transcription from RNA polymerase III promoter, response to estrogen stimulus, DNA binding, positive regulation of protein ubiquitination, zinc ion binding, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, negative regulation of transcription, RNA binding, regulation of cell proliferation, Breast cancer type 1 susceptibility protein, regulation of transcription from RNA polymerase II promoter, identical protein binding Molscript image for 3cojA01
3.40.50.10190.3.1.1.1.15 3cojB01 protein ubiquitination, chromosome segregation, Homo sapiens, response to ionizing radiation, breast cancer type 1 susceptibility protein, BRCA1-BARD1 complex, Acid--D-amino-acid ligases (peptide synthases)., apoptosis, negative regulation of fatty acid biosynthetic process, ribonucleoprotein complex, positive regulation of DNA repair, double-strand break repair via homologous recombination, postreplication repair, DNA damage response, signal transduction resulting in induction of apoptosis, enzyme binding, regulation of cell proliferation, RNA binding, negative regulation of transcription, regulation of transcription from RNA polymerase II promoter, identical protein binding, Breast cancer type 1 susceptibility protein, Ubiquitin mediated proteolysis, BRCA1-A complex, G2/M transition DNA damage checkpoint, zinc ion binding, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, DNA binding, regulation of transcription from RNA polymerase III promoter, response to estrogen stimulus, positive regulation of protein ubiquitination Molscript image for 3cojB01
3.40.50.10190.3.1.1.1.16 3cojC01 Acid--D-amino-acid ligases (peptide synthases)., negative regulation of fatty acid biosynthetic process, apoptosis, ribonucleoprotein complex, positive regulation of DNA repair, double-strand break repair via homologous recombination, DNA damage response, signal transduction resulting in induction of apoptosis, postreplication repair, enzyme binding, protein ubiquitination, chromosome segregation, Homo sapiens, response to ionizing radiation, breast cancer type 1 susceptibility protein, BRCA1-BARD1 complex, Ubiquitin mediated proteolysis, BRCA1-A complex, G2/M transition DNA damage checkpoint, zinc ion binding, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, response to estrogen stimulus, DNA binding, regulation of transcription from RNA polymerase III promoter, positive regulation of protein ubiquitination, regulation of cell proliferation, RNA binding, negative regulation of transcription, regulation of transcription from RNA polymerase II promoter, identical protein binding, Breast cancer type 1 susceptibility protein Molscript image for 3cojC01
3.40.50.10190.3.1.1.1.17 3cojG01 Ubiquitin mediated proteolysis, BRCA1-A complex, G2/M transition DNA damage checkpoint, zinc ion binding, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, DNA binding, regulation of transcription from RNA polymerase III promoter, response to estrogen stimulus, positive regulation of protein ubiquitination, regulation of cell proliferation, negative regulation of transcription, RNA binding, regulation of transcription from RNA polymerase II promoter, identical protein binding, Breast cancer type 1 susceptibility protein, negative regulation of fatty acid biosynthetic process, apoptosis, Acid--D-amino-acid ligases (peptide synthases)., ribonucleoprotein complex, positive regulation of DNA repair, DNA damage response, signal transduction resulting in induction of apoptosis, postreplication repair, double-strand break repair via homologous recombination, enzyme binding, protein ubiquitination, chromosome segregation, Homo sapiens, response to ionizing radiation, BRCA1-BARD1 complex, breast cancer type 1 susceptibility protein Molscript image for 3cojG01
3.40.50.10190.3.1.1.1.18 3cojX01 regulation of transcription from RNA polymerase II promoter, identical protein binding, Breast cancer type 1 susceptibility protein, regulation of cell proliferation, RNA binding, negative regulation of transcription, zinc ion binding, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, regulation of transcription from RNA polymerase III promoter, response to estrogen stimulus, DNA binding, positive regulation of protein ubiquitination, Ubiquitin mediated proteolysis, BRCA1-A complex, G2/M transition DNA damage checkpoint, chromosome segregation, Homo sapiens, response to ionizing radiation, breast cancer type 1 susceptibility protein, BRCA1-BARD1 complex, protein ubiquitination, ribonucleoprotein complex, positive regulation of DNA repair, double-strand break repair via homologous recombination, DNA damage response, signal transduction resulting in induction of apoptosis, postreplication repair, enzyme binding, Acid--D-amino-acid ligases (peptide synthases)., apoptosis, negative regulation of fatty acid biosynthetic process Molscript image for 3cojX01
3.40.50.10190.3.1.1.1.19 1t2vA01 protein ubiquitination, breast cancer type 1 susceptibility protein, BRCA1-BARD1 complex, Homo sapiens, response to ionizing radiation, chromosome segregation, Acid--D-amino-acid ligases (peptide synthases)., apoptosis, negative regulation of fatty acid biosynthetic process, enzyme binding, double-strand break repair via homologous recombination, DNA damage response, signal transduction resulting in induction of apoptosis, postreplication repair, positive regulation of DNA repair, ribonucleoprotein complex, RNA binding, negative regulation of transcription, regulation of cell proliferation, Breast cancer type 1 susceptibility protein, identical protein binding, regulation of transcription from RNA polymerase II promoter, G2/M transition DNA damage checkpoint, BRCA1-A complex, Ubiquitin mediated proteolysis, positive regulation of protein ubiquitination, response to estrogen stimulus, DNA binding, regulation of transcription from RNA polymerase III promoter, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, zinc ion binding Molscript image for 1t2vA01
3.40.50.10190.3.1.1.1.20 1t2vB01 enzyme binding, double-strand break repair via homologous recombination, postreplication repair, DNA damage response, signal transduction resulting in induction of apoptosis, positive regulation of DNA repair, ribonucleoprotein complex, Acid--D-amino-acid ligases (peptide synthases)., negative regulation of fatty acid biosynthetic process, apoptosis, breast cancer type 1 susceptibility protein, BRCA1-BARD1 complex, Homo sapiens, response to ionizing radiation, chromosome segregation, protein ubiquitination, positive regulation of protein ubiquitination, regulation of transcription from RNA polymerase III promoter, response to estrogen stimulus, DNA binding, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, zinc ion binding, G2/M transition DNA damage checkpoint, BRCA1-A complex, Ubiquitin mediated proteolysis, Breast cancer type 1 susceptibility protein, identical protein binding, regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, RNA binding, regulation of cell proliferation Molscript image for 1t2vB01
3.40.50.10190.3.1.1.1.21 1t2vC01 RNA binding, negative regulation of transcription, regulation of cell proliferation, Breast cancer type 1 susceptibility protein, identical protein binding, regulation of transcription from RNA polymerase II promoter, G2/M transition DNA damage checkpoint, BRCA1-A complex, Ubiquitin mediated proteolysis, positive regulation of protein ubiquitination, response to estrogen stimulus, regulation of transcription from RNA polymerase III promoter, DNA binding, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, zinc ion binding, protein ubiquitination, BRCA1-BARD1 complex, breast cancer type 1 susceptibility protein, Homo sapiens, response to ionizing radiation, chromosome segregation, apoptosis, negative regulation of fatty acid biosynthetic process, Acid--D-amino-acid ligases (peptide synthases)., enzyme binding, DNA damage response, signal transduction resulting in induction of apoptosis, postreplication repair, double-strand break repair via homologous recombination, positive regulation of DNA repair, ribonucleoprotein complex Molscript image for 1t2vC01
3.40.50.10190.3.1.1.1.22 1t2vD01 enzyme binding, DNA damage response, signal transduction resulting in induction of apoptosis, postreplication repair, double-strand break repair via homologous recombination, positive regulation of DNA repair, ribonucleoprotein complex, apoptosis, negative regulation of fatty acid biosynthetic process, Acid--D-amino-acid ligases (peptide synthases)., BRCA1-BARD1 complex, breast cancer type 1 susceptibility protein, Homo sapiens, response to ionizing radiation, chromosome segregation, protein ubiquitination, positive regulation of protein ubiquitination, regulation of transcription from RNA polymerase III promoter, DNA binding, response to estrogen stimulus, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, zinc ion binding, G2/M transition DNA damage checkpoint, BRCA1-A complex, Ubiquitin mediated proteolysis, Breast cancer type 1 susceptibility protein, identical protein binding, regulation of transcription from RNA polymerase II promoter, RNA binding, negative regulation of transcription, regulation of cell proliferation Molscript image for 1t2vD01
3.40.50.10190.3.1.1.1.23 1t2vE01 enzyme binding, double-strand break repair via homologous recombination, DNA damage response, signal transduction resulting in induction of apoptosis, postreplication repair, positive regulation of DNA repair, ribonucleoprotein complex, Acid--D-amino-acid ligases (peptide synthases)., negative regulation of fatty acid biosynthetic process, apoptosis, breast cancer type 1 susceptibility protein, BRCA1-BARD1 complex, Homo sapiens, response to ionizing radiation, chromosome segregation, protein ubiquitination, positive regulation of protein ubiquitination, DNA binding, response to estrogen stimulus, regulation of transcription from RNA polymerase III promoter, DNA damage response, signal transduction by p53 class mediator resulting in transcription of p21 class mediator, zinc ion binding, G2/M transition DNA damage checkpoint, BRCA1-A complex, Ubiquitin mediated proteolysis, Breast cancer type 1 susceptibility protein, identical protein binding, regulation of transcription from RNA polymerase II promoter, negative regulation of transcription, RNA binding, regulation of cell proliferation Molscript image for 1t2vE01

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
  • Multiple alignments for each functional family
  • Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
  • Detailed functional information on diversity and conservation within Functional families
  • Multi-domain architectures
In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages:
http://gene3d.biochem.ucl.ac.uk/superfamily/?accession=3.40.50.10190.3.1.1.1