S100 Family: 3.40.30.10.26.1.1.1

Representative domain: 2a2rA01

Classification Lineage (3.40.30.10.26.1.1.1)

CATH Code	Level Description	Links
3	Alpha Beta
3.40	3-Layer(aba) Sandwich
3.40.30	Glutaredoxin
3.40.30.10	Glutaredoxin	Gene3D
3.40.30.10.26
3.40.30.10.26.1
3.40.30.10.26.1.1
3.40.30.10.26.1.1.1

Summary of Non-Redundant Representatives


-	-	-	-	-	-	-	-	105

Non-Redundant Representatives (105)
Functional Families
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What is a Non-Redundant Representative?

CATH is a tree-like organisation of nodes that begins with the class node (i.e. the first branch-point of the tree) and ends with the domain nodes (i.e. the leaves of the tree). Each node below the class have a parent that they belong to, e.g. the parent of the H level (Homologous superfamily) is the T (Topology). Additionally, each node above the domains have child nodes that belong to them, e.g. the child nodes of a given H (Homologous superfamily) level are the S35 families (domains clustered at > 35% sequence identity).

S100 Count Entries in S100 Family 3.40.30.10.26.1.1.1 (105)

CATH code	Domain ID	Keywords
3.40.30.10.26.1.1.1.1	2a2rA01	Prostate cancer, Glutathione S-transferase P, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, anti-apoptosis, Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism, glutathione S-transferase [EC:2.5.1.18], central nervous system development, cytoplasm, Glutathione transferase.
3.40.30.10.26.1.1.1.2	2a2rB01	glutathione S-transferase [EC:2.5.1.18], central nervous system development, Glutathione transferase., cytoplasm, Prostate cancer, Glutathione S-transferase P, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, anti-apoptosis, Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism
3.40.30.10.26.1.1.1.3	3gusA01	central nervous system development, glutathione S-transferase [EC:2.5.1.18], cytoplasm, Glutathione transferase., Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens, protein binding, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, anti-apoptosis, Prostate cancer, Glutathione S-transferase P
3.40.30.10.26.1.1.1.4	3cshA01	cytoplasm, Glutathione transferase., glutathione S-transferase [EC:2.5.1.18], central nervous system development, Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, anti-apoptosis, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, Glutathione S-transferase P, Prostate cancer
3.40.30.10.26.1.1.1.5	3cshB01	cytoplasm, Glutathione transferase., glutathione S-transferase [EC:2.5.1.18], central nervous system development, Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism, Glutathione S-transferase P, Prostate cancer, anti-apoptosis, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding
3.40.30.10.26.1.1.1.6	3gusB01	anti-apoptosis, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, Glutathione S-transferase P, Prostate cancer, Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, Glutathione transferase., cytoplasm, glutathione S-transferase [EC:2.5.1.18], central nervous system development
3.40.30.10.26.1.1.1.7	3dgqA01	Glutathione S-transferase P, Prostate cancer, anti-apoptosis, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450, Glutathione transferase., cytoplasm, central nervous system development, glutathione S-transferase [EC:2.5.1.18]
3.40.30.10.26.1.1.1.8	3dgqB01	Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450, Prostate cancer, Glutathione S-transferase P, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, anti-apoptosis, central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione transferase., cytoplasm
3.40.30.10.26.1.1.1.9	2a2sA01	Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450, Glutathione S-transferase P, Prostate cancer, anti-apoptosis, protein binding, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, cytoplasm, Glutathione transferase., central nervous system development, glutathione S-transferase [EC:2.5.1.18]
3.40.30.10.26.1.1.1.10	2a2sB01	Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, anti-apoptosis, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, Glutathione S-transferase P, Prostate cancer, cytoplasm, Glutathione transferase., glutathione S-transferase [EC:2.5.1.18], central nervous system development
3.40.30.10.26.1.1.1.11	3hkrB01	glutathione S-transferase [EC:2.5.1.18], central nervous system development, cytoplasm, Glutathione transferase., Prostate cancer, Glutathione S-transferase P, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, anti-apoptosis, Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism
3.40.30.10.26.1.1.1.12	3ie3A01	central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione transferase., cytoplasm, Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, anti-apoptosis, Prostate cancer, Glutathione S-transferase P
3.40.30.10.26.1.1.1.13	1aqwA01	central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione transferase., cytoplasm, Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450, Prostate cancer, Glutathione S-transferase P, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, anti-apoptosis
3.40.30.10.26.1.1.1.14	1aqwB01	Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, anti-apoptosis, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, Glutathione S-transferase P, Prostate cancer, Glutathione transferase., cytoplasm, glutathione S-transferase [EC:2.5.1.18], central nervous system development
3.40.30.10.26.1.1.1.15	1aqwC01	Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens, anti-apoptosis, protein binding, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, Glutathione S-transferase P, Prostate cancer, cytoplasm, Glutathione transferase., central nervous system development, glutathione S-transferase [EC:2.5.1.18]
3.40.30.10.26.1.1.1.16	1aqwD01	Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens, anti-apoptosis, protein binding, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, Glutathione S-transferase P, Prostate cancer, cytoplasm, Glutathione transferase., central nervous system development, glutathione S-transferase [EC:2.5.1.18]
3.40.30.10.26.1.1.1.17	1pgtA01	Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, anti-apoptosis, Prostate cancer, Glutathione S-transferase P, Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, glutathione S-transferase [EC:2.5.1.18], central nervous system development, cytoplasm, Glutathione transferase.
3.40.30.10.26.1.1.1.18	1pgtB01	Prostate cancer, Glutathione S-transferase P, protein binding, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, anti-apoptosis, Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450, central nervous system development, glutathione S-transferase [EC:2.5.1.18], cytoplasm, Glutathione transferase.
3.40.30.10.26.1.1.1.19	3hkrA01	cytoplasm, Glutathione transferase., central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens, anti-apoptosis, protein binding, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, Glutathione S-transferase P, Prostate cancer
3.40.30.10.26.1.1.1.20	3ie3B01	Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, anti-apoptosis, Prostate cancer, Glutathione S-transferase P, central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione transferase., cytoplasm
3.40.30.10.26.1.1.1.21	3csjA01	Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens, protein binding, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, anti-apoptosis, Prostate cancer, Glutathione S-transferase P, central nervous system development, glutathione S-transferase [EC:2.5.1.18], cytoplasm, Glutathione transferase.
3.40.30.10.26.1.1.1.22	3csjB01	Glutathione transferase., cytoplasm, glutathione S-transferase [EC:2.5.1.18], central nervous system development, Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, anti-apoptosis, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, Glutathione S-transferase P, Prostate cancer
3.40.30.10.26.1.1.1.23	13gsA01	central nervous system development, glutathione S-transferase [EC:2.5.1.18], cytoplasm, Glutathione transferase., Prostate cancer, Glutathione S-transferase P, protein binding, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, anti-apoptosis, Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450
3.40.30.10.26.1.1.1.24	13gsB01	glutathione S-transferase [EC:2.5.1.18], central nervous system development, Glutathione transferase., cytoplasm, Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, anti-apoptosis, Prostate cancer, Glutathione S-transferase P
3.40.30.10.26.1.1.1.25	16gsA01	Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450, Glutathione S-transferase P, Prostate cancer, anti-apoptosis, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, Glutathione transferase., cytoplasm, central nervous system development, glutathione S-transferase [EC:2.5.1.18]
3.40.30.10.26.1.1.1.26	16gsB01	Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, anti-apoptosis, Prostate cancer, Glutathione S-transferase P, glutathione S-transferase [EC:2.5.1.18], central nervous system development, cytoplasm, Glutathione transferase.
3.40.30.10.26.1.1.1.27	18gsA01	Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism, Prostate cancer, Glutathione S-transferase P, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, anti-apoptosis, glutathione S-transferase [EC:2.5.1.18], central nervous system development, Glutathione transferase., cytoplasm
3.40.30.10.26.1.1.1.28	18gsB01	central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione transferase., cytoplasm, Prostate cancer, Glutathione S-transferase P, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, anti-apoptosis, Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450
3.40.30.10.26.1.1.1.29	19gsA01	Glutathione S-transferase P, Prostate cancer, anti-apoptosis, protein binding, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450, cytoplasm, Glutathione transferase., central nervous system development, glutathione S-transferase [EC:2.5.1.18]
3.40.30.10.26.1.1.1.30	19gsB01	Glutathione transferase., cytoplasm, glutathione S-transferase [EC:2.5.1.18], central nervous system development, Glutathione S-transferase P, Prostate cancer, anti-apoptosis, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism
3.40.30.10.26.1.1.1.31	2gssA01	glutathione S-transferase [EC:2.5.1.18], central nervous system development, cytoplasm, Glutathione transferase., Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism, Prostate cancer, Glutathione S-transferase P, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, anti-apoptosis
3.40.30.10.26.1.1.1.32	2gssB01	Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450, Glutathione S-transferase P, Prostate cancer, anti-apoptosis, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, Glutathione transferase., cytoplasm, central nervous system development, glutathione S-transferase [EC:2.5.1.18]
3.40.30.10.26.1.1.1.33	2pgtA01	central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione transferase., cytoplasm, Prostate cancer, Glutathione S-transferase P, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, anti-apoptosis, Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450
3.40.30.10.26.1.1.1.34	2pgtB01	Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism, Prostate cancer, Glutathione S-transferase P, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, anti-apoptosis, glutathione S-transferase [EC:2.5.1.18], central nervous system development, Glutathione transferase., cytoplasm
3.40.30.10.26.1.1.1.35	3csiA01	glutathione S-transferase [EC:2.5.1.18], central nervous system development, cytoplasm, Glutathione transferase., Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, anti-apoptosis, Prostate cancer, Glutathione S-transferase P
3.40.30.10.26.1.1.1.36	3csiB01	Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450, Prostate cancer, Glutathione S-transferase P, protein binding, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, anti-apoptosis, central nervous system development, glutathione S-transferase [EC:2.5.1.18], cytoplasm, Glutathione transferase.
3.40.30.10.26.1.1.1.37	3csiC01	central nervous system development, glutathione S-transferase [EC:2.5.1.18], cytoplasm, Glutathione transferase., Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450, Prostate cancer, Glutathione S-transferase P, protein binding, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, anti-apoptosis
3.40.30.10.26.1.1.1.38	3csiD01	Glutathione S-transferase P, Prostate cancer, anti-apoptosis, protein binding, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450, cytoplasm, Glutathione transferase., central nervous system development, glutathione S-transferase [EC:2.5.1.18]
3.40.30.10.26.1.1.1.39	3gssA01	cytoplasm, Glutathione transferase., glutathione S-transferase [EC:2.5.1.18], central nervous system development, anti-apoptosis, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, Glutathione S-transferase P, Prostate cancer, Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens
3.40.30.10.26.1.1.1.40	3gssB01	cytoplasm, Glutathione transferase., glutathione S-transferase [EC:2.5.1.18], central nervous system development, Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, anti-apoptosis, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, Glutathione S-transferase P, Prostate cancer
3.40.30.10.26.1.1.1.41	6gssA01	Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens, protein binding, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, anti-apoptosis, Prostate cancer, Glutathione S-transferase P, central nervous system development, glutathione S-transferase [EC:2.5.1.18], cytoplasm, Glutathione transferase.
3.40.30.10.26.1.1.1.42	6gssB01	glutathione S-transferase [EC:2.5.1.18], central nervous system development, Glutathione transferase., cytoplasm, Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, anti-apoptosis, Prostate cancer, Glutathione S-transferase P
3.40.30.10.26.1.1.1.43	8gssA01	Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, anti-apoptosis, Prostate cancer, Glutathione S-transferase P, glutathione S-transferase [EC:2.5.1.18], central nervous system development, Glutathione transferase., cytoplasm
3.40.30.10.26.1.1.1.44	8gssB01	Glutathione S-transferase P, Prostate cancer, anti-apoptosis, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism, cytoplasm, Glutathione transferase., glutathione S-transferase [EC:2.5.1.18], central nervous system development
3.40.30.10.26.1.1.1.45	8gssC01	Glutathione transferase., cytoplasm, glutathione S-transferase [EC:2.5.1.18], central nervous system development, Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, anti-apoptosis, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, Glutathione S-transferase P, Prostate cancer
3.40.30.10.26.1.1.1.46	3hjoA01	Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450, Glutathione S-transferase P, Prostate cancer, anti-apoptosis, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, Glutathione transferase., cytoplasm, central nervous system development, glutathione S-transferase [EC:2.5.1.18]
3.40.30.10.26.1.1.1.47	3hjoB01	Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism, Prostate cancer, Glutathione S-transferase P, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, anti-apoptosis, glutathione S-transferase [EC:2.5.1.18], central nervous system development, Glutathione transferase., cytoplasm
3.40.30.10.26.1.1.1.48	1aqvA01	Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism, Prostate cancer, Glutathione S-transferase P, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, anti-apoptosis, glutathione S-transferase [EC:2.5.1.18], central nervous system development, cytoplasm, Glutathione transferase.
3.40.30.10.26.1.1.1.49	1aqvB01	central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione transferase., cytoplasm, Prostate cancer, Glutathione S-transferase P, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, anti-apoptosis, Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450
3.40.30.10.26.1.1.1.50	5gssA01	Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism, Prostate cancer, Glutathione S-transferase P, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, anti-apoptosis, glutathione S-transferase [EC:2.5.1.18], central nervous system development, Glutathione transferase., cytoplasm
3.40.30.10.26.1.1.1.51	5gssB01	Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, anti-apoptosis, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, Glutathione S-transferase P, Prostate cancer, Glutathione transferase., cytoplasm, glutathione S-transferase [EC:2.5.1.18], central nervous system development
3.40.30.10.26.1.1.1.52	9gssA01	central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione transferase., cytoplasm, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, anti-apoptosis, Prostate cancer, Glutathione S-transferase P, Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens
3.40.30.10.26.1.1.1.53	9gssB01	Glutathione transferase., cytoplasm, central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens, anti-apoptosis, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, Glutathione S-transferase P, Prostate cancer
3.40.30.10.26.1.1.1.54	1aqxA01	glutathione S-transferase [EC:2.5.1.18], central nervous system development, cytoplasm, Glutathione transferase., Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism, Prostate cancer, Glutathione S-transferase P, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, anti-apoptosis
3.40.30.10.26.1.1.1.55	1aqxB01	cytoplasm, Glutathione transferase., glutathione S-transferase [EC:2.5.1.18], central nervous system development, anti-apoptosis, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, Glutathione S-transferase P, Prostate cancer, Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens
3.40.30.10.26.1.1.1.56	1aqxC01	Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism, Prostate cancer, Glutathione S-transferase P, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, anti-apoptosis, glutathione S-transferase [EC:2.5.1.18], central nervous system development, cytoplasm, Glutathione transferase.
3.40.30.10.26.1.1.1.57	1aqxD01	anti-apoptosis, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, Glutathione S-transferase P, Prostate cancer, Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens, Glutathione transferase., cytoplasm, central nervous system development, glutathione S-transferase [EC:2.5.1.18]
3.40.30.10.26.1.1.1.58	1kbnA01	Prostate cancer, Glutathione S-transferase P, protein binding, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, anti-apoptosis, Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450, central nervous system development, glutathione S-transferase [EC:2.5.1.18], cytoplasm, Glutathione transferase.
3.40.30.10.26.1.1.1.59	1kbnB01	Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, anti-apoptosis, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, Glutathione S-transferase P, Prostate cancer, Glutathione transferase., cytoplasm, glutathione S-transferase [EC:2.5.1.18], central nervous system development
3.40.30.10.26.1.1.1.60	1md3A01	cytoplasm, Glutathione transferase., glutathione S-transferase [EC:2.5.1.18], central nervous system development, anti-apoptosis, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, Glutathione S-transferase P, Prostate cancer, Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens
3.40.30.10.26.1.1.1.61	1md3B01	Glutathione transferase., cytoplasm, central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens, anti-apoptosis, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, Glutathione S-transferase P, Prostate cancer
3.40.30.10.26.1.1.1.62	1px7A01	Glutathione transferase., cytoplasm, central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens, anti-apoptosis, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, Glutathione S-transferase P, Prostate cancer
3.40.30.10.26.1.1.1.63	1px7B01	Glutathione transferase., cytoplasm, central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione S-transferase P, Prostate cancer, anti-apoptosis, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450
3.40.30.10.26.1.1.1.64	12gsA01	Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism, Prostate cancer, Glutathione S-transferase P, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, anti-apoptosis, glutathione S-transferase [EC:2.5.1.18], central nervous system development, cytoplasm, Glutathione transferase.
3.40.30.10.26.1.1.1.65	12gsB01	cytoplasm, Glutathione transferase., glutathione S-transferase [EC:2.5.1.18], central nervous system development, anti-apoptosis, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, Glutathione S-transferase P, Prostate cancer, Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens
3.40.30.10.26.1.1.1.66	1eogA01	central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione transferase., cytoplasm, Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, anti-apoptosis, Prostate cancer, Glutathione S-transferase P
3.40.30.10.26.1.1.1.67	1eogB01	Glutathione transferase., cytoplasm, glutathione S-transferase [EC:2.5.1.18], central nervous system development, Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism, Glutathione S-transferase P, Prostate cancer, anti-apoptosis, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding
3.40.30.10.26.1.1.1.68	1md4A01	cytoplasm, Glutathione transferase., central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione S-transferase P, Prostate cancer, anti-apoptosis, protein binding, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450
3.40.30.10.26.1.1.1.69	1md4B01	Prostate cancer, Glutathione S-transferase P, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, anti-apoptosis, Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450, central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione transferase., cytoplasm
3.40.30.10.26.1.1.1.70	1px6A01	glutathione S-transferase [EC:2.5.1.18], central nervous system development, cytoplasm, Glutathione transferase., Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, anti-apoptosis, Prostate cancer, Glutathione S-transferase P
3.40.30.10.26.1.1.1.71	1px6B01	Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, anti-apoptosis, Prostate cancer, Glutathione S-transferase P, Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, glutathione S-transferase [EC:2.5.1.18], central nervous system development, cytoplasm, Glutathione transferase.
3.40.30.10.26.1.1.1.72	1zgnA01	Glutathione transferase., cytoplasm, central nervous system development, glutathione S-transferase [EC:2.5.1.18], anti-apoptosis, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, Glutathione S-transferase P, Prostate cancer, Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens
3.40.30.10.26.1.1.1.73	1zgnB01	Glutathione transferase., cytoplasm, glutathione S-transferase [EC:2.5.1.18], central nervous system development, Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism, Glutathione S-transferase P, Prostate cancer, anti-apoptosis, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding
3.40.30.10.26.1.1.1.74	3hjmA01	Glutathione transferase., cytoplasm, central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens, anti-apoptosis, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, Glutathione S-transferase P, Prostate cancer
3.40.30.10.26.1.1.1.75	3hjmB01	central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione transferase., cytoplasm, Prostate cancer, Glutathione S-transferase P, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, anti-apoptosis, Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450
3.40.30.10.26.1.1.1.76	3hjmC01	Glutathione transferase., cytoplasm, central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens, anti-apoptosis, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, Glutathione S-transferase P, Prostate cancer
3.40.30.10.26.1.1.1.77	3hjmD01	Glutathione transferase., cytoplasm, glutathione S-transferase [EC:2.5.1.18], central nervous system development, Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism, Glutathione S-transferase P, Prostate cancer, anti-apoptosis, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding
3.40.30.10.26.1.1.1.78	4pgtA01	Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, anti-apoptosis, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, Glutathione S-transferase P, Prostate cancer, cytoplasm, Glutathione transferase., glutathione S-transferase [EC:2.5.1.18], central nervous system development
3.40.30.10.26.1.1.1.79	4pgtB01	Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism, Glutathione S-transferase P, Prostate cancer, anti-apoptosis, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, cytoplasm, Glutathione transferase., glutathione S-transferase [EC:2.5.1.18], central nervous system development
3.40.30.10.26.1.1.1.80	3pgtA01	Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism, Glutathione S-transferase P, Prostate cancer, anti-apoptosis, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, Glutathione transferase., cytoplasm, glutathione S-transferase [EC:2.5.1.18], central nervous system development
3.40.30.10.26.1.1.1.81	3pgtB01	glutathione S-transferase [EC:2.5.1.18], central nervous system development, Glutathione transferase., cytoplasm, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, anti-apoptosis, Prostate cancer, Glutathione S-transferase P, Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens
3.40.30.10.26.1.1.1.82	3dd3A01	Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, anti-apoptosis, Prostate cancer, Glutathione S-transferase P, Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, glutathione S-transferase [EC:2.5.1.18], central nervous system development, cytoplasm, Glutathione transferase.
3.40.30.10.26.1.1.1.83	10gsA01	central nervous system development, glutathione S-transferase [EC:2.5.1.18], cytoplasm, Glutathione transferase., Prostate cancer, Glutathione S-transferase P, protein binding, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, anti-apoptosis, Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450
3.40.30.10.26.1.1.1.84	10gsB01	glutathione S-transferase [EC:2.5.1.18], central nervous system development, Glutathione transferase., cytoplasm, Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, anti-apoptosis, Prostate cancer, Glutathione S-transferase P
3.40.30.10.26.1.1.1.85	7gssA01	central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione transferase., cytoplasm, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, anti-apoptosis, Prostate cancer, Glutathione S-transferase P, Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens
3.40.30.10.26.1.1.1.86	7gssB01	Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding, anti-apoptosis, Prostate cancer, Glutathione S-transferase P, glutathione S-transferase [EC:2.5.1.18], central nervous system development, cytoplasm, Glutathione transferase.
3.40.30.10.26.1.1.1.87	3dd3B01	anti-apoptosis, protein binding, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, Glutathione S-transferase P, Prostate cancer, Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens, cytoplasm, Glutathione transferase., central nervous system development, glutathione S-transferase [EC:2.5.1.18]
3.40.30.10.26.1.1.1.88	11gsA01	Glutathione transferase., cytoplasm, central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens, anti-apoptosis, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, Glutathione S-transferase P, Prostate cancer
3.40.30.10.26.1.1.1.89	11gsB01	protein binding, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, anti-apoptosis, Prostate cancer, Glutathione S-transferase P, Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens, central nervous system development, glutathione S-transferase [EC:2.5.1.18], cytoplasm, Glutathione transferase.
3.40.30.10.26.1.1.1.90	20gsA01	glutathione S-transferase [EC:2.5.1.18], central nervous system development, Glutathione transferase., cytoplasm, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, anti-apoptosis, Prostate cancer, Glutathione S-transferase P, Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens
3.40.30.10.26.1.1.1.91	20gsB01	Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450, Glutathione S-transferase P, Prostate cancer, anti-apoptosis, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, Glutathione transferase., cytoplasm, central nervous system development, glutathione S-transferase [EC:2.5.1.18]
3.40.30.10.26.1.1.1.92	1eohA01	Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, anti-apoptosis, Prostate cancer, Glutathione S-transferase P, glutathione S-transferase [EC:2.5.1.18], central nervous system development, Glutathione transferase., cytoplasm
3.40.30.10.26.1.1.1.93	1eohB01	glutathione S-transferase [EC:2.5.1.18], central nervous system development, Glutathione transferase., cytoplasm, Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, anti-apoptosis, Prostate cancer, Glutathione S-transferase P
3.40.30.10.26.1.1.1.94	1eohC01	glutathione S-transferase [EC:2.5.1.18], central nervous system development, Glutathione transferase., cytoplasm, Prostate cancer, Glutathione S-transferase P, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, anti-apoptosis, Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism
3.40.30.10.26.1.1.1.95	1eohD01	cytoplasm, Glutathione transferase., glutathione S-transferase [EC:2.5.1.18], central nervous system development, Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism, Glutathione S-transferase P, Prostate cancer, anti-apoptosis, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, protein binding
3.40.30.10.26.1.1.1.96	1eohE01	Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism, Prostate cancer, Glutathione S-transferase P, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, anti-apoptosis, glutathione S-transferase [EC:2.5.1.18], central nervous system development, Glutathione transferase., cytoplasm
3.40.30.10.26.1.1.1.97	1eohF01	Glutathione S-transferase P, Prostate cancer, anti-apoptosis, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450, Glutathione transferase., cytoplasm, central nervous system development, glutathione S-transferase [EC:2.5.1.18]
3.40.30.10.26.1.1.1.98	1eohG01	cytoplasm, Glutathione transferase., central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione S-transferase P, Prostate cancer, anti-apoptosis, protein binding, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450
3.40.30.10.26.1.1.1.99	1eohH01	glutathione S-transferase [EC:2.5.1.18], central nervous system development, Glutathione transferase., cytoplasm, Homo sapiens, Drug metabolism - cytochrome P450, Glutathione metabolism, Prostate cancer, Glutathione S-transferase P, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, anti-apoptosis
3.40.30.10.26.1.1.1.100	4gssA01	Drug metabolism - cytochrome P450, Glutathione metabolism, Homo sapiens, anti-apoptosis, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, protein binding, Glutathione S-transferase P, Prostate cancer, Glutathione transferase., cytoplasm, glutathione S-transferase [EC:2.5.1.18], central nervous system development
3.40.30.10.26.1.1.1.101	4gssB01	cytoplasm, Glutathione transferase., central nervous system development, glutathione S-transferase [EC:2.5.1.18], Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450, Glutathione S-transferase P, Prostate cancer, anti-apoptosis, protein binding, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer
3.40.30.10.26.1.1.1.102	1gssA01	central nervous system development, glutathione S-transferase [EC:2.5.1.18], Glutathione transferase., cytoplasm, Prostate cancer, Glutathione S-transferase P, protein binding, Pathways in cancer, Metabolism of xenobiotics by cytochrome P450, anti-apoptosis, Homo sapiens, Glutathione metabolism, Drug metabolism - cytochrome P450
3.40.30.10.26.1.1.1.103	1gssB01	central nervous system development, glutathione S-transferase [EC:2.5.1.18], cytoplasm, Glutathione transferase., protein binding, Metabolism of xenobiotics by cytochrome P450, Pathways in cancer, anti-apoptosis, Prostate cancer, Glutathione S-transferase P, Glutathione metabolism, Drug metabolism - cytochrome P450, Homo sapiens
3.40.30.10.26.1.1.1.104	21gsA01
3.40.30.10.26.1.1.1.105	21gsB01

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:

Multiple alignments for each functional family
Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
Detailed functional information on diversity and conservation within Functional families
Multi-domain architectures

In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages:

http://gene3d.biochem.ucl.ac.uk/superfamily/?accession=3.40.30.10.26.1.1.1

What is a Non-Redundant Representative?

Why can't I have a multiple structural alignment of the whole superfamily?

The simple answer is that some of the larger superfamilies in CATH comprise relatives which are very structurally diverse, having different secondary structure embellishments. Attempting to provide a global alignment of all domains in the superfamily would result in poor quality alignments. As a result, structural alignments in CATH are generated by first clustering together the structures that have at least some recognisable structural similarity using a normalised RMSD score (SIMAX = RMSDxNumber of residues in the largest domain/number of aligned residues) less than a given cutoff.

What is an Close Structural Cluster?

A Close Structural Cluster describes a cluster of two or more CATH domains that have been grouped together due to their close structural similarity (SIMAX score < 5Å where SIMAX = RMSD x Number of residues in the larger domain/number of aligned residues).

What is a Distant Structural Cluster?

A Distant Structural Cluster describes a cluster of two or CATH domains that have been grouped together with a more relaxed structural similarity threshold to investigate more distant evolutionary similarities (SIMAX score < 5Å where SIMAX = RMSD x Number of residues in the larger domain/number of aligned residues).

What is a Structural Neighbour?

The term "structural neighbour" is used here to describe two CATH domains that share a degree of structural similarity. The SSAP algorithm is used to calculate this similarity and works by generating a structure-based pairwise alignment of the two domains then scoring this alignment using a RMSD score which has been normalised by the length of the larger domain divided by the number of aligned residues (SIMAX).

S100 Family: 3.40.30.10.26.1.1.1

Classification Lineage (3.40.30.10.26.1.1.1)

Summary of Non-Redundant Representatives

What is a Non-Redundant Representative?

S100 Count Entries in S100 Family 3.40.30.10.26.1.1.1 (105)

What is a Non-Redundant Representative?

Why can't I have a multiple structural alignment of the whole superfamily?

What is an Close Structural Cluster?

What is a Distant Structural Cluster?

What is a Structural Neighbour?

CATH Shortcuts