S100 Family: 3.30.9.10.7.1.1.1

Representative domain: 3g3eA02

Classification Lineage (3.30.9.10.7.1.1.1)

CATH Code	Level Description	Links
3	Alpha Beta
3.30	2-Layer Sandwich
3.30.9	D-Amino Acid Oxidase; Chain A, domain 2
3.30.9.10	D-Amino Acid Oxidase, subunit A, domain 2	Gene3D
3.30.9.10.7
3.30.9.10.7.1
3.30.9.10.7.1.1
3.30.9.10.7.1.1.1

Summary of Non-Redundant Representatives


-	-	-	-	-	-	-	-	28

Non-Redundant Representatives (28)
Functional Families
Help

What is a Non-Redundant Representative?

CATH is a tree-like organisation of nodes that begins with the class node (i.e. the first branch-point of the tree) and ends with the domain nodes (i.e. the leaves of the tree). Each node below the class have a parent that they belong to, e.g. the parent of the H level (Homologous superfamily) is the T (Topology). Additionally, each node above the domains have child nodes that belong to them, e.g. the child nodes of a given H (Homologous superfamily) level are the S35 families (domains clustered at > 35% sequence identity).

S100 Count Entries in S100 Family 3.30.9.10.7.1.1.1 (28)

CATH code	Domain ID	Keywords
3.30.9.10.7.1.1.1.1	3g3eA02	Arginine and proline metabolism, D-amino-acid oxidase activity, Peroxisome, D-amino-acid oxidase., D-amino-acid oxidase, Homo sapiens, Glycine, serine and threonine metabolism, Metabolic pathways, D-Arginine and D-ornithine metabolism, D-amino-acid oxidase [EC:1.4.3.3]
3.30.9.10.7.1.1.1.2	3g3eB02	Peroxisome, Homo sapiens, D-amino-acid oxidase, D-amino-acid oxidase., D-amino-acid oxidase [EC:1.4.3.3], Metabolic pathways, D-Arginine and D-ornithine metabolism, Glycine, serine and threonine metabolism, Arginine and proline metabolism, D-amino-acid oxidase activity
3.30.9.10.7.1.1.1.3	3g3eC02	Arginine and proline metabolism, D-amino-acid oxidase activity, Metabolic pathways, D-Arginine and D-ornithine metabolism, D-amino-acid oxidase [EC:1.4.3.3], Glycine, serine and threonine metabolism, Homo sapiens, D-amino-acid oxidase., D-amino-acid oxidase, Peroxisome
3.30.9.10.7.1.1.1.4	3g3eD02	D-amino-acid oxidase activity, Arginine and proline metabolism, Glycine, serine and threonine metabolism, D-amino-acid oxidase [EC:1.4.3.3], D-Arginine and D-ornithine metabolism, Metabolic pathways, D-amino-acid oxidase, D-amino-acid oxidase., Homo sapiens, Peroxisome
3.30.9.10.7.1.1.1.5	3cukA02	Glycine, serine and threonine metabolism, D-amino-acid oxidase [EC:1.4.3.3], D-Arginine and D-ornithine metabolism, Metabolic pathways, Peroxisome, D-amino-acid oxidase, D-amino-acid oxidase., Homo sapiens, D-amino-acid oxidase activity, Arginine and proline metabolism
3.30.9.10.7.1.1.1.6	3cukB02	Arginine and proline metabolism, D-amino-acid oxidase activity, Glycine, serine and threonine metabolism, Metabolic pathways, D-Arginine and D-ornithine metabolism, D-amino-acid oxidase [EC:1.4.3.3], D-amino-acid oxidase., D-amino-acid oxidase, Homo sapiens, Peroxisome
3.30.9.10.7.1.1.1.7	3cukC02	Arginine and proline metabolism, D-amino-acid oxidase activity, Peroxisome, D-amino-acid oxidase., D-amino-acid oxidase, Homo sapiens, Glycine, serine and threonine metabolism, Metabolic pathways, D-Arginine and D-ornithine metabolism, D-amino-acid oxidase [EC:1.4.3.3]
3.30.9.10.7.1.1.1.8	3cukD02	D-amino-acid oxidase., D-amino-acid oxidase, Homo sapiens, Peroxisome, Glycine, serine and threonine metabolism, D-Arginine and D-ornithine metabolism, Metabolic pathways, D-amino-acid oxidase [EC:1.4.3.3], D-amino-acid oxidase activity, Arginine and proline metabolism
3.30.9.10.7.1.1.1.9	2du8A02	Arginine and proline metabolism, D-amino-acid oxidase activity, D-amino-acid oxidase, D-amino-acid oxidase., Homo sapiens, Peroxisome, Glycine, serine and threonine metabolism, D-amino-acid oxidase [EC:1.4.3.3], Metabolic pathways, D-Arginine and D-ornithine metabolism
3.30.9.10.7.1.1.1.10	2du8B02	Glycine, serine and threonine metabolism, D-amino-acid oxidase [EC:1.4.3.3], D-Arginine and D-ornithine metabolism, Metabolic pathways, D-amino-acid oxidase, D-amino-acid oxidase., Homo sapiens, Peroxisome, D-amino-acid oxidase activity, Arginine and proline metabolism
3.30.9.10.7.1.1.1.11	2du8G02	Glycine, serine and threonine metabolism, D-amino-acid oxidase [EC:1.4.3.3], D-Arginine and D-ornithine metabolism, Metabolic pathways, D-amino-acid oxidase, D-amino-acid oxidase., Homo sapiens, Peroxisome, D-amino-acid oxidase activity, Arginine and proline metabolism
3.30.9.10.7.1.1.1.12	2du8J02	Peroxisome, Homo sapiens, D-amino-acid oxidase, D-amino-acid oxidase., D-amino-acid oxidase [EC:1.4.3.3], D-Arginine and D-ornithine metabolism, Metabolic pathways, Glycine, serine and threonine metabolism, D-amino-acid oxidase activity, Arginine and proline metabolism
3.30.9.10.7.1.1.1.13	2e4aA02	D-amino-acid oxidase activity, Arginine and proline metabolism, Peroxisome, Homo sapiens, D-amino-acid oxidase., D-amino-acid oxidase, D-Arginine and D-ornithine metabolism, Metabolic pathways, D-amino-acid oxidase [EC:1.4.3.3], Glycine, serine and threonine metabolism
3.30.9.10.7.1.1.1.14	2e4aB02	Peroxisome, D-amino-acid oxidase., D-amino-acid oxidase, Homo sapiens, Glycine, serine and threonine metabolism, Metabolic pathways, D-Arginine and D-ornithine metabolism, D-amino-acid oxidase [EC:1.4.3.3], Arginine and proline metabolism, D-amino-acid oxidase activity
3.30.9.10.7.1.1.1.15	2e4aC02	D-amino-acid oxidase activity, Arginine and proline metabolism, D-amino-acid oxidase, D-amino-acid oxidase., Homo sapiens, Peroxisome, Glycine, serine and threonine metabolism, D-amino-acid oxidase [EC:1.4.3.3], D-Arginine and D-ornithine metabolism, Metabolic pathways
3.30.9.10.7.1.1.1.16	2e4aD02	D-amino-acid oxidase activity, Arginine and proline metabolism, Peroxisome, Homo sapiens, D-amino-acid oxidase, D-amino-acid oxidase., D-amino-acid oxidase [EC:1.4.3.3], D-Arginine and D-ornithine metabolism, Metabolic pathways, Glycine, serine and threonine metabolism
3.30.9.10.7.1.1.1.17	2e82A02	Glycine, serine and threonine metabolism, D-Arginine and D-ornithine metabolism, Metabolic pathways, D-amino-acid oxidase [EC:1.4.3.3], Peroxisome, D-amino-acid oxidase., D-amino-acid oxidase, Homo sapiens, D-amino-acid oxidase activity, Arginine and proline metabolism
3.30.9.10.7.1.1.1.18	2e82B02	D-amino-acid oxidase, D-amino-acid oxidase., Homo sapiens, Peroxisome, Glycine, serine and threonine metabolism, D-amino-acid oxidase [EC:1.4.3.3], D-Arginine and D-ornithine metabolism, Metabolic pathways, D-amino-acid oxidase activity, Arginine and proline metabolism
3.30.9.10.7.1.1.1.19	2e82C02	Arginine and proline metabolism, D-amino-acid oxidase activity, Homo sapiens, D-amino-acid oxidase, D-amino-acid oxidase., Peroxisome, D-amino-acid oxidase [EC:1.4.3.3], Metabolic pathways, D-Arginine and D-ornithine metabolism, Glycine, serine and threonine metabolism
3.30.9.10.7.1.1.1.20	2e82D02	Arginine and proline metabolism, D-amino-acid oxidase activity, Glycine, serine and threonine metabolism, Metabolic pathways, D-Arginine and D-ornithine metabolism, D-amino-acid oxidase [EC:1.4.3.3], D-amino-acid oxidase., D-amino-acid oxidase, Homo sapiens, Peroxisome
3.30.9.10.7.1.1.1.21	2e48A02	Glycine, serine and threonine metabolism, D-Arginine and D-ornithine metabolism, Metabolic pathways, D-amino-acid oxidase [EC:1.4.3.3], D-amino-acid oxidase., D-amino-acid oxidase, Homo sapiens, Peroxisome, D-amino-acid oxidase activity, Arginine and proline metabolism
3.30.9.10.7.1.1.1.22	2e48B02	D-amino-acid oxidase activity, Arginine and proline metabolism, Glycine, serine and threonine metabolism, D-amino-acid oxidase [EC:1.4.3.3], D-Arginine and D-ornithine metabolism, Metabolic pathways, Peroxisome, D-amino-acid oxidase, D-amino-acid oxidase., Homo sapiens
3.30.9.10.7.1.1.1.23	2e48C02	Arginine and proline metabolism, D-amino-acid oxidase activity, Homo sapiens, D-amino-acid oxidase., D-amino-acid oxidase, Peroxisome, Metabolic pathways, D-Arginine and D-ornithine metabolism, D-amino-acid oxidase [EC:1.4.3.3], Glycine, serine and threonine metabolism
3.30.9.10.7.1.1.1.24	2e48D02	D-amino-acid oxidase activity, Arginine and proline metabolism, Peroxisome, D-amino-acid oxidase., D-amino-acid oxidase, Homo sapiens, Glycine, serine and threonine metabolism, D-Arginine and D-ornithine metabolism, Metabolic pathways, D-amino-acid oxidase [EC:1.4.3.3]
3.30.9.10.7.1.1.1.25	2e49A02	D-amino-acid oxidase activity, Arginine and proline metabolism, D-Arginine and D-ornithine metabolism, Metabolic pathways, D-amino-acid oxidase [EC:1.4.3.3], Glycine, serine and threonine metabolism, Peroxisome, Homo sapiens, D-amino-acid oxidase., D-amino-acid oxidase
3.30.9.10.7.1.1.1.26	2e49B02	D-amino-acid oxidase activity, Arginine and proline metabolism, Glycine, serine and threonine metabolism, D-Arginine and D-ornithine metabolism, Metabolic pathways, D-amino-acid oxidase [EC:1.4.3.3], Peroxisome, D-amino-acid oxidase., D-amino-acid oxidase, Homo sapiens
3.30.9.10.7.1.1.1.27	2e49C02	Arginine and proline metabolism, D-amino-acid oxidase activity, D-amino-acid oxidase [EC:1.4.3.3], Metabolic pathways, D-Arginine and D-ornithine metabolism, Glycine, serine and threonine metabolism, Homo sapiens, D-amino-acid oxidase, D-amino-acid oxidase., Peroxisome
3.30.9.10.7.1.1.1.28	2e49D02	D-amino-acid oxidase., D-amino-acid oxidase, Homo sapiens, Peroxisome, Glycine, serine and threonine metabolism, Metabolic pathways, D-Arginine and D-ornithine metabolism, D-amino-acid oxidase [EC:1.4.3.3], Arginine and proline metabolism, D-amino-acid oxidase activity

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:

Multiple alignments for each functional family
Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
Detailed functional information on diversity and conservation within Functional families
Multi-domain architectures

In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages:

http://gene3d.biochem.ucl.ac.uk/superfamily/?accession=3.30.9.10.7.1.1.1

What is a Non-Redundant Representative?

Why can't I have a multiple structural alignment of the whole superfamily?

The simple answer is that some of the larger superfamilies in CATH comprise relatives which are very structurally diverse, having different secondary structure embellishments. Attempting to provide a global alignment of all domains in the superfamily would result in poor quality alignments. As a result, structural alignments in CATH are generated by first clustering together the structures that have at least some recognisable structural similarity using a normalised RMSD score (SIMAX = RMSDxNumber of residues in the largest domain/number of aligned residues) less than a given cutoff.

What is an Close Structural Cluster?

A Close Structural Cluster describes a cluster of two or more CATH domains that have been grouped together due to their close structural similarity (SIMAX score < 5Å where SIMAX = RMSD x Number of residues in the larger domain/number of aligned residues).

What is a Distant Structural Cluster?

A Distant Structural Cluster describes a cluster of two or CATH domains that have been grouped together with a more relaxed structural similarity threshold to investigate more distant evolutionary similarities (SIMAX score < 5Å where SIMAX = RMSD x Number of residues in the larger domain/number of aligned residues).

What is a Structural Neighbour?

The term "structural neighbour" is used here to describe two CATH domains that share a degree of structural similarity. The SSAP algorithm is used to calculate this similarity and works by generating a structure-based pairwise alignment of the two domains then scoring this alignment using a RMSD score which has been normalised by the length of the larger domain divided by the number of aligned residues (SIMAX).

S100 Family: 3.30.9.10.7.1.1.1

Classification Lineage (3.30.9.10.7.1.1.1)

Summary of Non-Redundant Representatives

What is a Non-Redundant Representative?

S100 Count Entries in S100 Family 3.30.9.10.7.1.1.1 (28)

What is a Non-Redundant Representative?

Why can't I have a multiple structural alignment of the whole superfamily?

What is an Close Structural Cluster?

What is a Distant Structural Cluster?

What is a Structural Neighbour?

CATH Shortcuts