S100 Family: 3.30.590.10.2.1.1.1

Representative domain: 2bvcA02

Classification Lineage (3.30.590.10.2.1.1.1)

CATH Code	Level Description	Links
3	Alpha Beta
3.30	2-Layer Sandwich
3.30.590	Creatine Kinase; Chain A, domain 2
3.30.590.10	Creatine Kinase; Chain	Gene3D
3.30.590.10.2
3.30.590.10.2.1
3.30.590.10.2.1.1
3.30.590.10.2.1.1.1

Summary of Non-Redundant Representatives


-	-	-	-	-	-	-	-	72

Non-Redundant Representatives (72)
Functional Families
Help

What is a Non-Redundant Representative?

CATH is a tree-like organisation of nodes that begins with the class node (i.e. the first branch-point of the tree) and ends with the domain nodes (i.e. the leaves of the tree). Each node below the class have a parent that they belong to, e.g. the parent of the H level (Homologous superfamily) is the T (Topology). Additionally, each node above the domains have child nodes that belong to them, e.g. the child nodes of a given H (Homologous superfamily) level are the S35 families (domains clustered at > 35% sequence identity).

S100 Count Entries in S100 Family 3.30.590.10.2.1.1.1 (72)

CATH code	Domain ID	Keywords
3.30.590.10.2.1.1.1.1	2bvcA02	Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Glutamine synthetase 1, Metabolic pathways, Two-component system, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2]
3.30.590.10.2.1.1.1.2	2bvcB02	Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Metabolic pathways, Two-component system, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism
3.30.590.10.2.1.1.1.3	2bvcC02	Two-component system, Metabolic pathways, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Glutamine synthetase 1, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism
3.30.590.10.2.1.1.1.4	2bvcD02	Glutamate--ammonia ligase., Mycobacterium tuberculosis, Metabolic pathways, Two-component system, Glutamine synthetase 1, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism
3.30.590.10.2.1.1.1.5	2bvcE02	Glutamate--ammonia ligase., Mycobacterium tuberculosis, Two-component system, Metabolic pathways, Glutamine synthetase 1, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism
3.30.590.10.2.1.1.1.6	2bvcF02	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Metabolic pathways, Two-component system
3.30.590.10.2.1.1.1.7	2whiA02	Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Two-component system, Metabolic pathways, Glutamine synthetase 1, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism
3.30.590.10.2.1.1.1.8	2whiB02	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Two-component system, Metabolic pathways
3.30.590.10.2.1.1.1.9	2whiC02	Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Metabolic pathways, Two-component system, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Glutamine synthetase 1, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism
3.30.590.10.2.1.1.1.10	2whiD02	glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Two-component system, Metabolic pathways, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Glutamine synthetase 1, Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism
3.30.590.10.2.1.1.1.11	2whiE02	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Two-component system, Metabolic pathways
3.30.590.10.2.1.1.1.12	2whiF02	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Two-component system, Metabolic pathways, Glutamate--ammonia ligase., Mycobacterium tuberculosis
3.30.590.10.2.1.1.1.13	1htoA01	Two-component system, Metabolic pathways, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Glutamine synthetase 1, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism
3.30.590.10.2.1.1.1.14	1htoB01	Glutamate--ammonia ligase., Mycobacterium tuberculosis, Two-component system, Metabolic pathways, Glutamine synthetase 1, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism
3.30.590.10.2.1.1.1.15	1htoC01	Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Two-component system, Metabolic pathways, Glutamine synthetase 1, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism
3.30.590.10.2.1.1.1.16	1htoD01	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Two-component system, Metabolic pathways
3.30.590.10.2.1.1.1.17	1htoE01	Glutamine synthetase 1, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Two-component system, Metabolic pathways, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism
3.30.590.10.2.1.1.1.18	1htoF01	Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Glutamine synthetase 1, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Two-component system, Metabolic pathways, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2]
3.30.590.10.2.1.1.1.19	1htoG01	glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Two-component system, Metabolic pathways, Glutamine synthetase 1, Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism
3.30.590.10.2.1.1.1.20	1htoH01	Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Two-component system, Metabolic pathways, Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism
3.30.590.10.2.1.1.1.21	1htoI01	Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Glutamine synthetase 1, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Metabolic pathways, Two-component system, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2]
3.30.590.10.2.1.1.1.22	1htoJ01	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Two-component system, Metabolic pathways
3.30.590.10.2.1.1.1.23	1htoK01	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Metabolic pathways, Two-component system, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Glutamine synthetase 1
3.30.590.10.2.1.1.1.24	1htoL01	Glutamine synthetase 1, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Two-component system, Metabolic pathways, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism
3.30.590.10.2.1.1.1.25	1htoM01	glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Metabolic pathways, Two-component system, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Glutamine synthetase 1, Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism
3.30.590.10.2.1.1.1.26	1htoN01	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Two-component system, Metabolic pathways, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Glutamine synthetase 1
3.30.590.10.2.1.1.1.27	1htoO01	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Metabolic pathways, Two-component system, Mycobacterium tuberculosis, Glutamate--ammonia ligase.
3.30.590.10.2.1.1.1.28	1htoP01	Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Metabolic pathways, Two-component system, Glutamine synthetase 1, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism
3.30.590.10.2.1.1.1.29	1htoQ01	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Two-component system, Metabolic pathways
3.30.590.10.2.1.1.1.30	1htoR01	Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Two-component system, Metabolic pathways, Glutamine synthetase 1, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism
3.30.590.10.2.1.1.1.31	1htoS01	Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Two-component system, Metabolic pathways, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism
3.30.590.10.2.1.1.1.32	1htoT01	Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Metabolic pathways, Two-component system, Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism
3.30.590.10.2.1.1.1.33	1htoU01	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Two-component system, Metabolic pathways, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Glutamine synthetase 1
3.30.590.10.2.1.1.1.34	1htoV01	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Two-component system, Metabolic pathways, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Glutamine synthetase 1
3.30.590.10.2.1.1.1.35	1htoW01	Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Glutamine synthetase 1, Two-component system, Metabolic pathways, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2]
3.30.590.10.2.1.1.1.36	1htoX01	Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Metabolic pathways, Two-component system, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism
3.30.590.10.2.1.1.1.37	1htqA01	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Two-component system, Metabolic pathways, Mycobacterium tuberculosis, Glutamate--ammonia ligase.
3.30.590.10.2.1.1.1.38	1htqB01	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Two-component system, Metabolic pathways, Glutamine synthetase 1
3.30.590.10.2.1.1.1.39	1htqC01	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Two-component system, Metabolic pathways, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Glutamine synthetase 1
3.30.590.10.2.1.1.1.40	1htqD01	Two-component system, Metabolic pathways, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Glutamine synthetase 1, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism
3.30.590.10.2.1.1.1.41	1htqE01	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Two-component system, Metabolic pathways, Mycobacterium tuberculosis, Glutamate--ammonia ligase.
3.30.590.10.2.1.1.1.42	1htqF01	Glutamine synthetase 1, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Two-component system, Metabolic pathways, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism
3.30.590.10.2.1.1.1.43	1htqG01	Glutamate--ammonia ligase., Mycobacterium tuberculosis, Two-component system, Metabolic pathways, Glutamine synthetase 1, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism
3.30.590.10.2.1.1.1.44	1htqH01	Glutamine synthetase 1, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Metabolic pathways, Two-component system, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism
3.30.590.10.2.1.1.1.45	1htqI01	Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Two-component system, Metabolic pathways, Glutamine synthetase 1, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism
3.30.590.10.2.1.1.1.46	1htqJ01	Glutamine synthetase 1, Metabolic pathways, Two-component system, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism
3.30.590.10.2.1.1.1.47	1htqK01	Glutamine synthetase 1, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Two-component system, Metabolic pathways, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism
3.30.590.10.2.1.1.1.48	1htqL01	Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Glutamine synthetase 1, Metabolic pathways, Two-component system, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2]
3.30.590.10.2.1.1.1.49	1htqM01	Glutamate--ammonia ligase., Mycobacterium tuberculosis, Metabolic pathways, Two-component system, Glutamine synthetase 1, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism
3.30.590.10.2.1.1.1.50	1htqN01	Glutamine synthetase 1, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Metabolic pathways, Two-component system, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism
3.30.590.10.2.1.1.1.51	1htqO01	Glutamine synthetase 1, Two-component system, Metabolic pathways, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism
3.30.590.10.2.1.1.1.52	1htqP01	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Two-component system, Metabolic pathways, Glutamine synthetase 1
3.30.590.10.2.1.1.1.53	1htqQ01	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Metabolic pathways, Two-component system
3.30.590.10.2.1.1.1.54	1htqR01	glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Metabolic pathways, Two-component system, Glutamine synthetase 1, Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism
3.30.590.10.2.1.1.1.55	1htqS01	Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Two-component system, Metabolic pathways, Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism
3.30.590.10.2.1.1.1.56	1htqT01	Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Two-component system, Metabolic pathways, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Glutamine synthetase 1, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism
3.30.590.10.2.1.1.1.57	1htqU01	Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Two-component system, Metabolic pathways, Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism
3.30.590.10.2.1.1.1.58	1htqV01	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Two-component system, Metabolic pathways
3.30.590.10.2.1.1.1.59	1htqW01	Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Glutamine synthetase 1, Metabolic pathways, Two-component system, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2]
3.30.590.10.2.1.1.1.60	1htqX01	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Two-component system, Metabolic pathways, Mycobacterium tuberculosis, Glutamate--ammonia ligase.
3.30.590.10.2.1.1.1.61	2wgsA02	Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism, Glutamine synthetase 1, Metabolic pathways, Two-component system, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2]
3.30.590.10.2.1.1.1.62	2wgsB02	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Two-component system, Metabolic pathways, Glutamate--ammonia ligase., Mycobacterium tuberculosis
3.30.590.10.2.1.1.1.63	2wgsC02	Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Metabolic pathways, Two-component system, Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism
3.30.590.10.2.1.1.1.64	2wgsD02	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Two-component system, Metabolic pathways, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Glutamine synthetase 1
3.30.590.10.2.1.1.1.65	2wgsE02	Glutamine synthetase 1, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Two-component system, Metabolic pathways, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism
3.30.590.10.2.1.1.1.66	2wgsF02	Mycobacterium tuberculosis, Glutamate--ammonia ligase., Two-component system, Metabolic pathways, Glutamine synthetase 1, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism
3.30.590.10.2.1.1.1.67	2wgsG02	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Metabolic pathways, Two-component system, Glutamate--ammonia ligase., Mycobacterium tuberculosis
3.30.590.10.2.1.1.1.68	2wgsH02	Glutamine synthetase 1, Metabolic pathways, Two-component system, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism
3.30.590.10.2.1.1.1.69	2wgsI02	Nitrogen metabolism, glutamine synthetase [EC:6.3.1.2], Glutamine synthetase 1, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Two-component system, Metabolic pathways, Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism
3.30.590.10.2.1.1.1.70	2wgsJ02	Glutamate--ammonia ligase., Mycobacterium tuberculosis, Metabolic pathways, Two-component system, Glutamine synthetase 1, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Alanine, aspartate and glutamate metabolism, Arginine and proline metabolism
3.30.590.10.2.1.1.1.71	2wgsK02	Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism, glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Glutamate--ammonia ligase., Mycobacterium tuberculosis, Metabolic pathways, Two-component system, Glutamine synthetase 1
3.30.590.10.2.1.1.1.72	2wgsL02	glutamine synthetase [EC:6.3.1.2], Nitrogen metabolism, Mycobacterium tuberculosis, Glutamate--ammonia ligase., Metabolic pathways, Two-component system, Glutamine synthetase 1, Arginine and proline metabolism, Alanine, aspartate and glutamate metabolism

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:

Multiple alignments for each functional family
Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
Detailed functional information on diversity and conservation within Functional families
Multi-domain architectures

In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages:

http://gene3d.biochem.ucl.ac.uk/superfamily/?accession=3.30.590.10.2.1.1.1

What is a Non-Redundant Representative?

Why can't I have a multiple structural alignment of the whole superfamily?

The simple answer is that some of the larger superfamilies in CATH comprise relatives which are very structurally diverse, having different secondary structure embellishments. Attempting to provide a global alignment of all domains in the superfamily would result in poor quality alignments. As a result, structural alignments in CATH are generated by first clustering together the structures that have at least some recognisable structural similarity using a normalised RMSD score (SIMAX = RMSDxNumber of residues in the largest domain/number of aligned residues) less than a given cutoff.

What is an Close Structural Cluster?

A Close Structural Cluster describes a cluster of two or more CATH domains that have been grouped together due to their close structural similarity (SIMAX score < 5Å where SIMAX = RMSD x Number of residues in the larger domain/number of aligned residues).

What is a Distant Structural Cluster?

A Distant Structural Cluster describes a cluster of two or CATH domains that have been grouped together with a more relaxed structural similarity threshold to investigate more distant evolutionary similarities (SIMAX score < 5Å where SIMAX = RMSD x Number of residues in the larger domain/number of aligned residues).

What is a Structural Neighbour?

The term "structural neighbour" is used here to describe two CATH domains that share a degree of structural similarity. The SSAP algorithm is used to calculate this similarity and works by generating a structure-based pairwise alignment of the two domains then scoring this alignment using a RMSD score which has been normalised by the length of the larger domain divided by the number of aligned residues (SIMAX).

S100 Family: 3.30.590.10.2.1.1.1

Classification Lineage (3.30.590.10.2.1.1.1)

Summary of Non-Redundant Representatives

What is a Non-Redundant Representative?

S100 Count Entries in S100 Family 3.30.590.10.2.1.1.1 (72)

What is a Non-Redundant Representative?

Why can't I have a multiple structural alignment of the whole superfamily?

What is an Close Structural Cluster?

What is a Distant Structural Cluster?

What is a Structural Neighbour?

CATH Shortcuts