S100 Family: 3.30.497.10.5.1.1.1
Representative domain: 1lj5A01
Classification Lineage (3.30.497.10.5.1.1.1)
Summary of Non-Redundant Representatives
 |  |  |  |  |  |  |  |  |
|---|---|---|---|---|---|---|---|---|
| - | - | - | - | - | - | - | - | 4 |
S100 Count Entries in S100 Family 3.30.497.10.5.1.1.1 (4)
| CATH Level | CATH code | Domain ID | Keywords | Thumbnail |
|---|---|---|---|---|
|
3.30.497.10.5.1.1.1.1 | 1lj5A01 | chronological cell aging, negative regulation of apoptosis, p53 signaling pathway, regulation of receptor activity, negative regulation of plasminogen activation, positive regulation of inflammatory response, positive regulation of receptor-mediated endocytosis, extracellular matrix, positive regulation of angiogenesis, cellular response to chemical stimulus, Plasminogen activator inhibitor 1, extracellular space, defense response to Gram-negative bacterium, plasminogen activator inhibitor-1, Homo sapiens, negative regulation of smooth muscle cell migration, negative regulation of vascular wound healing, Complement and coagulation cascades, cellular response to lipopolysaccharide, negative regulation of fibrinolysis, Chagas disease, negative regulation of endopeptidase activity, positive regulation of monocyte chemotaxis, protease binding, negative regulation of cell adhesion mediated by integrin, positive regulation of interleukin-8 production, serine-type endopeptidase inhibitor activity | |
|
3.30.497.10.5.1.1.1.2 | 1dvnA01 | negative regulation of cell adhesion mediated by integrin, positive regulation of interleukin-8 production, serine-type endopeptidase inhibitor activity, Complement and coagulation cascades, cellular response to lipopolysaccharide, negative regulation of fibrinolysis, protease binding, Chagas disease, positive regulation of monocyte chemotaxis, negative regulation of endopeptidase activity, defense response to Gram-negative bacterium, plasminogen activator inhibitor-1, extracellular space, Homo sapiens, negative regulation of smooth muscle cell migration, negative regulation of vascular wound healing, p53 signaling pathway, negative regulation of plasminogen activation, positive regulation of inflammatory response, regulation of receptor activity, negative regulation of apoptosis, chronological cell aging, positive regulation of receptor-mediated endocytosis, extracellular matrix, positive regulation of angiogenesis, Plasminogen activator inhibitor 1, cellular response to chemical stimulus | |
|
3.30.497.10.5.1.1.1.3 | 9paiA01 | plasminogen activator inhibitor-1, defense response to Gram-negative bacterium, extracellular space, Homo sapiens, negative regulation of vascular wound healing, negative regulation of smooth muscle cell migration, negative regulation of plasminogen activation, regulation of receptor activity, positive regulation of inflammatory response, p53 signaling pathway, negative regulation of apoptosis, chronological cell aging, extracellular matrix, positive regulation of receptor-mediated endocytosis, positive regulation of angiogenesis, Plasminogen activator inhibitor 1, cellular response to chemical stimulus, negative regulation of cell adhesion mediated by integrin, positive regulation of interleukin-8 production, serine-type endopeptidase inhibitor activity, Complement and coagulation cascades, cellular response to lipopolysaccharide, negative regulation of fibrinolysis, protease binding, Chagas disease, positive regulation of monocyte chemotaxis, negative regulation of endopeptidase activity | |
|
3.30.497.10.5.1.1.1.4 | 1c5gA01 | extracellular space, defense response to Gram-negative bacterium, plasminogen activator inhibitor-1, Homo sapiens, negative regulation of smooth muscle cell migration, negative regulation of vascular wound healing, negative regulation of apoptosis, chronological cell aging, p53 signaling pathway, positive regulation of inflammatory response, regulation of receptor activity, negative regulation of plasminogen activation, positive regulation of receptor-mediated endocytosis, extracellular matrix, positive regulation of angiogenesis, cellular response to chemical stimulus, Plasminogen activator inhibitor 1, negative regulation of cell adhesion mediated by integrin, positive regulation of interleukin-8 production, serine-type endopeptidase inhibitor activity, Complement and coagulation cascades, cellular response to lipopolysaccharide, negative regulation of fibrinolysis, Chagas disease, negative regulation of endopeptidase activity, positive regulation of monocyte chemotaxis, protease binding |
The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
- Multiple alignments for each functional family
- Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
- Detailed functional information on diversity and conservation within Functional families
- Multi-domain architectures