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CATH Superfamily 3.30.460.30

Glutamyl-tRNA reductase, N-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Glutamyl-tRNA reductase, N-terminal domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Glutamyl-tRNA reductase, N-terminal domain

Structural domains comprising this superfamily share the structure of the N-terminal domain of glutamyl-tRNA reductase (GluTR), which catalyses the first step in tetrapyrrole biosynthesis by the C5 pathway. According to available literature this N-terminal domain is the catalytic domain PMID:24753615. Catalysis requires NADPH as a cofactor.

GO Diversity

Unique GO annotations
11 Unique GO terms

EC Diversity

Unique EC annotations
3 Unique EC terms

Species Diversity

Unique species annotations
8397 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 7
Domain clusters (>95% seq id): 2
Domain clusters (>35% seq id): 2
Unique PDBs: 4
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 3
Function
Unique EC: 3
Unique GO: 11
Taxonomy
Unique Species: 8397
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