S100 Family: 3.30.420.10.18.1.1.1

Representative domain: 2rkiA05

Classification Lineage (3.30.420.10.18.1.1.1)

CATH Code	Level Description	Links
3	Alpha Beta
3.30	2-Layer Sandwich
3.30.420	Nucleotidyltransferase; domain 5
3.30.420.10		Gene3D
3.30.420.10.18
3.30.420.10.18.1
3.30.420.10.18.1.1
3.30.420.10.18.1.1.1

Summary of Non-Redundant Representatives


-	-	-	-	-	-	-	-	83

Non-Redundant Representatives (83)
Functional Families
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What is a Non-Redundant Representative?

CATH is a tree-like organisation of nodes that begins with the class node (i.e. the first branch-point of the tree) and ends with the domain nodes (i.e. the leaves of the tree). Each node below the class have a parent that they belong to, e.g. the parent of the H level (Homologous superfamily) is the T (Topology). Additionally, each node above the domains have child nodes that belong to them, e.g. the child nodes of a given H (Homologous superfamily) level are the S35 families (domains clustered at > 35% sequence identity).

S100 Count Entries in S100 Family 3.30.420.10.18.1.1.1 (83)

CATH code	Domain ID	Keywords
3.30.420.10.18.1.1.1.1	2rkiA05	DNA-directed DNA polymerase., Retroviral ribonuclease H., RNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.2	3dyaA05	DNA-directed DNA polymerase., Retroviral ribonuclease H., RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.3	3lakA05	HIV-1 M:B_HXB2R, DNA-directed DNA polymerase., Retroviral ribonuclease H., Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.4	1rthA05	HIV-1 M:B_HXB2R, DNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, RNA-directed DNA polymerase., Retroviral ribonuclease H.
3.30.420.10.18.1.1.1.5	2rf2A05	HIV-1 M:B_HXB2R, DNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase., Retroviral ribonuclease H.
3.30.420.10.18.1.1.1.6	3dlgA05	HIV-1 retropepsin., Gag-Pol polyprotein, RNA-directed DNA polymerase., Retroviral ribonuclease H., DNA-directed DNA polymerase., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.7	1jkhA05	HIV-1 M:B_HXB2R, RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, Retroviral ribonuclease H., DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.8	3lalA05	RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, Retroviral ribonuclease H., DNA-directed DNA polymerase., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.9	1rtjA05	HIV-1 M:B_HXB2R, DNA-directed DNA polymerase., Retroviral ribonuclease H., RNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin.
3.30.420.10.18.1.1.1.10	1jlaA05	HIV-1 M:B_HXB2R, Retroviral ribonuclease H., RNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin., DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.11	2opsA05	HIV-1 M:B_HXB2R, DNA-directed DNA polymerase., Retroviral ribonuclease H., RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein
3.30.420.10.18.1.1.1.12	3lanA05	HIV-1 M:B_HXB2R, DNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase., Retroviral ribonuclease H.
3.30.420.10.18.1.1.1.13	3drpA05	DNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, RNA-directed DNA polymerase., Retroviral ribonuclease H., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.14	3ffiA05	Retroviral ribonuclease H., RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, DNA-directed DNA polymerase., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.15	3di6A05	HIV-1 M:B_HXB2R, Retroviral ribonuclease H., Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase., DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.16	1s1tA05	HIV-1 retropepsin., Gag-Pol polyprotein, RNA-directed DNA polymerase., Retroviral ribonuclease H., DNA-directed DNA polymerase., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.17	3c6tA05	DNA-directed DNA polymerase., RNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin., Retroviral ribonuclease H., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.18	3c6uA05	DNA-directed DNA polymerase., Retroviral ribonuclease H., RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.19	3i0sA05	DNA-directed DNA polymerase., Retroviral ribonuclease H., Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.20	3kk1A05	HIV-1 M:B_HXB2R, DNA-directed DNA polymerase., Retroviral ribonuclease H., RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein
3.30.420.10.18.1.1.1.21	1vrtA05	HIV-1 M:B_HXB2R, DNA-directed DNA polymerase., Retroviral ribonuclease H., HIV-1 retropepsin., Gag-Pol polyprotein, RNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.22	1c1bA05	Retroviral ribonuclease H., RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, DNA-directed DNA polymerase., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.23	1rt2A05	HIV-1 M:B_HXB2R, DNA-directed DNA polymerase., Retroviral ribonuclease H., Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.24	3lamA05	Retroviral ribonuclease H., HIV-1 retropepsin., Gag-Pol polyprotein, RNA-directed DNA polymerase., DNA-directed DNA polymerase., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.25	3dleA05	HIV-1 M:B_HXB2R, DNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, RNA-directed DNA polymerase., Retroviral ribonuclease H.
3.30.420.10.18.1.1.1.26	2wonA05	HIV-1 M:B_HXB2R, DNA-directed DNA polymerase., Retroviral ribonuclease H., Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.27	1c0uA05	HIV-1 M:B_HXB2R, Retroviral ribonuclease H., Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase., DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.28	1c1cA05	DNA-directed DNA polymerase., Retroviral ribonuclease H., Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.29	3dolA05	Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase., Retroviral ribonuclease H., DNA-directed DNA polymerase., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.30	1lwfA05	DNA-directed DNA polymerase., RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, Retroviral ribonuclease H., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.31	1rt1A05	DNA-directed DNA polymerase., RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, Retroviral ribonuclease H., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.32	1ep4A05	HIV-1 M:B_HXB2R, RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, Retroviral ribonuclease H., DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.33	1lweA05	Retroviral ribonuclease H., Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase., DNA-directed DNA polymerase., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.34	1jlfA05	Retroviral ribonuclease H., RNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin., DNA-directed DNA polymerase., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.35	3drrA05	HIV-1 M:B_HXB2R, Retroviral ribonuclease H., Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase., DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.36	3kk2A05	DNA-directed DNA polymerase., Retroviral ribonuclease H., RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.37	3kk3A05	HIV-1 M:B_HXB2R, RNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin., Retroviral ribonuclease H., DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.38	1s1vA05	HIV-1 M:B_HXB2R, Retroviral ribonuclease H., RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.39	3dmjA05	HIV-1 M:B_HXB2R, DNA-directed DNA polymerase., Retroviral ribonuclease H., HIV-1 retropepsin., Gag-Pol polyprotein, RNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.40	1vruA05	HIV-1 M:B_HXB2R, RNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin., Retroviral ribonuclease H., DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.41	1jlgA05	HIV-1 M:B_HXB2R, DNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase., Retroviral ribonuclease H.
3.30.420.10.18.1.1.1.42	1klmA05	HIV-1 retropepsin., Gag-Pol polyprotein, RNA-directed DNA polymerase., Retroviral ribonuclease H., DNA-directed DNA polymerase., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.43	3e01A05	HIV-1 retropepsin., Gag-Pol polyprotein, RNA-directed DNA polymerase., Retroviral ribonuclease H., DNA-directed DNA polymerase., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.44	1jlbA05	HIV-1 M:B_HXB2R, Retroviral ribonuclease H., HIV-1 retropepsin., Gag-Pol polyprotein, RNA-directed DNA polymerase., DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.45	2oppA05	HIV-1 M:B_HXB2R, DNA-directed DNA polymerase., RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, Retroviral ribonuclease H.
3.30.420.10.18.1.1.1.46	1s1xA05	HIV-1 M:B_HXB2R, Retroviral ribonuclease H., RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.47	2jleA05	Reverse transcriptase/RNaseH, Human immunodeficiency virus 1
3.30.420.10.18.1.1.1.48	1fk9A05	HIV-1 M:B_HXB2R, HIV-1 retropepsin., Gag-Pol polyprotein, RNA-directed DNA polymerase., Retroviral ribonuclease H., DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.49	1c0tA05	HIV-1 M:B_HXB2R, RNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin., Retroviral ribonuclease H., DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.50	2womA05	HIV-1 M:B_HXB2R, HIV-1 retropepsin., Gag-Pol polyprotein, RNA-directed DNA polymerase., Retroviral ribonuclease H., DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.51	1rt6A05	HIV-1 M:B_HXB2R, DNA-directed DNA polymerase., Retroviral ribonuclease H., Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.52	2hndA05	HIV-1 M:B_HXB2R, DNA-directed DNA polymerase., RNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin., Retroviral ribonuclease H.
3.30.420.10.18.1.1.1.53	2hnyA05	HIV-1 M:B_HXB2R, Retroviral ribonuclease H., RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.54	3kjvA05	Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase., Retroviral ribonuclease H., DNA-directed DNA polymerase., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.55	1fkoA05	Retroviral ribonuclease H., HIV-1 retropepsin., Gag-Pol polyprotein, RNA-directed DNA polymerase., DNA-directed DNA polymerase., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.56	1jleA05	HIV-1 M:B_HXB2R, DNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase., Retroviral ribonuclease H.
3.30.420.10.18.1.1.1.57	1fkpA05	DNA-directed DNA polymerase., Retroviral ribonuclease H., RNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.58	1revA05	HIV-1 M:B_HXB2R, DNA-directed DNA polymerase., Retroviral ribonuclease H., HIV-1 retropepsin., Gag-Pol polyprotein, RNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.59	1tkxA05	HIV-1 M:B_HXB2R, HIV-1 retropepsin., Gag-Pol polyprotein, RNA-directed DNA polymerase., Retroviral ribonuclease H., DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.60	3i0rA05	HIV-1 M:B_HXB2R, DNA-directed DNA polymerase., RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, Retroviral ribonuclease H.
3.30.420.10.18.1.1.1.61	1rt4A05	HIV-1 M:B_HXB2R, RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, Retroviral ribonuclease H., DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.62	1rt5A05	Retroviral ribonuclease H., RNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin., DNA-directed DNA polymerase., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.63	2oprA05	HIV-1 M:B_HXB2R, Retroviral ribonuclease H., RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.64	1jlcA05	Retroviral ribonuclease H., Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase., DNA-directed DNA polymerase., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.65	1rtiA05	DNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase., Retroviral ribonuclease H., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.66	3dokA05	DNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, RNA-directed DNA polymerase., Retroviral ribonuclease H., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.67	1tktA05	Retroviral ribonuclease H., HIV-1 retropepsin., Gag-Pol polyprotein, RNA-directed DNA polymerase., DNA-directed DNA polymerase., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.68	1dttA05	DNA-directed DNA polymerase., Retroviral ribonuclease H., RNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.69	1s1wA05	HIV-1 M:B_HXB2R, Retroviral ribonuclease H., Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase., DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.70	3drsA05	HIV-1 M:B_HXB2R, Retroviral ribonuclease H., RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.71	1jlqA05	DNA-directed DNA polymerase., Retroviral ribonuclease H., RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.72	1rt7A05	Retroviral ribonuclease H., RNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin., DNA-directed DNA polymerase., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.73	1dtqA05	HIV-1 M:B_HXB2R, Retroviral ribonuclease H., HIV-1 retropepsin., Gag-Pol polyprotein, RNA-directed DNA polymerase., DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.74	3dm2A05	DNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase., Retroviral ribonuclease H., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.75	1lw0A05	HIV-1 M:B_HXB2R, Retroviral ribonuclease H., Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase., DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.76	1tl3A05	DNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase., Retroviral ribonuclease H., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.77	2opqA05	HIV-1 M:B_HXB2R, Retroviral ribonuclease H., Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase., DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.78	1tkzA05	HIV-1 M:B_HXB2R, DNA-directed DNA polymerase., RNA-directed DNA polymerase., HIV-1 retropepsin., Gag-Pol polyprotein, Retroviral ribonuclease H.
3.30.420.10.18.1.1.1.79	1tl1A05	DNA-directed DNA polymerase., Retroviral ribonuclease H., RNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.80	1s1uA05	HIV-1 retropepsin., Gag-Pol polyprotein, RNA-directed DNA polymerase., Retroviral ribonuclease H., DNA-directed DNA polymerase., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.81	1lw2A05	HIV-1 M:B_HXB2R, RNA-directed DNA polymerase., Gag-Pol polyprotein, HIV-1 retropepsin., Retroviral ribonuclease H., DNA-directed DNA polymerase.
3.30.420.10.18.1.1.1.82	1rt3A05	Retroviral ribonuclease H., HIV-1 retropepsin., Gag-Pol polyprotein, RNA-directed DNA polymerase., DNA-directed DNA polymerase., HIV-1 M:B_HXB2R
3.30.420.10.18.1.1.1.83	2hnzA05	HIV-1 M:B_HXB2R, Gag-Pol polyprotein, HIV-1 retropepsin., RNA-directed DNA polymerase., Retroviral ribonuclease H., DNA-directed DNA polymerase.

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:

Multiple alignments for each functional family
Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
Detailed functional information on diversity and conservation within Functional families
Multi-domain architectures

In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages:

http://gene3d.biochem.ucl.ac.uk/superfamily/?accession=3.30.420.10.18.1.1.1

What is a Non-Redundant Representative?

Why can't I have a multiple structural alignment of the whole superfamily?

The simple answer is that some of the larger superfamilies in CATH comprise relatives which are very structurally diverse, having different secondary structure embellishments. Attempting to provide a global alignment of all domains in the superfamily would result in poor quality alignments. As a result, structural alignments in CATH are generated by first clustering together the structures that have at least some recognisable structural similarity using a normalised RMSD score (SIMAX = RMSDxNumber of residues in the largest domain/number of aligned residues) less than a given cutoff.

What is an Close Structural Cluster?

A Close Structural Cluster describes a cluster of two or more CATH domains that have been grouped together due to their close structural similarity (SIMAX score < 5Å where SIMAX = RMSD x Number of residues in the larger domain/number of aligned residues).

What is a Distant Structural Cluster?

A Distant Structural Cluster describes a cluster of two or CATH domains that have been grouped together with a more relaxed structural similarity threshold to investigate more distant evolutionary similarities (SIMAX score < 5Å where SIMAX = RMSD x Number of residues in the larger domain/number of aligned residues).

What is a Structural Neighbour?

The term "structural neighbour" is used here to describe two CATH domains that share a degree of structural similarity. The SSAP algorithm is used to calculate this similarity and works by generating a structure-based pairwise alignment of the two domains then scoring this alignment using a RMSD score which has been normalised by the length of the larger domain divided by the number of aligned residues (SIMAX).

S100 Family: 3.30.420.10.18.1.1.1

Classification Lineage (3.30.420.10.18.1.1.1)

Summary of Non-Redundant Representatives

What is a Non-Redundant Representative?

S100 Count Entries in S100 Family 3.30.420.10.18.1.1.1 (83)

What is a Non-Redundant Representative?

Why can't I have a multiple structural alignment of the whole superfamily?

What is an Close Structural Cluster?

What is a Distant Structural Cluster?

What is a Structural Neighbour?

CATH Shortcuts