The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.
3.30.300.20
superfamily
Functional Families
Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
Superfamily: K homology (KH) domain
This entry represents the KH domain, which is an RNA-binding domain important for post-translational activities DOI:10.1016/B978-0-12-809633-8.20662-6. A conserved glycine-rich GXXG motif is characteristic of the majority of KH domains. The KH domain contains three alpha-helices and a three-stranded anti-parallel beta-sheet PMID:27166440. There are two different versions of the KH motif, type I (commonly found in eukaryotic proteins) and type II (commonly found in prokaryotic proteins) PMID:18422648. The prokaryotic KH domain has been found in a number of proteins, including the N-terminal domain of the S3 ribosomal protein PMID:11014182, the C-terminal domain of Era GTPase PMID:10411886 and the two C-terminal domains of the NusA transcription factor PMID:11430821.
GO Diversity
Unique GO annotations
154 Unique GO terms
EC Diversity
Unique EC annotations
2 Unique EC terms
Species Diversity
Unique species annotations
25202 Unique species
Sequence/Structure Diversity
Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.
Superfamily Summary
A general summary of information for this superfamily.
| Structures | |
|---|---|
| Domains: | 529 |
| Domain clusters (>95% seq id): | 58 |
| Domain clusters (>35% seq id): | 30 |
| Unique PDBs: | 470 |
| Alignments | |
| Structural Clusters (5A): | 6 |
| Structural Clusters (9A): | 3 |
| FunFam Clusters: | 83 |
| Function | |
| Unique EC: | 2 |
| Unique GO: | 154 |
| Taxonomy | |
| Unique Species: | 25202 |
