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CATH Superfamily 3.30.2460.20

Wnt (Wingless and Int-1), C-terminal domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Wnt (Wingless and Int-1), C-terminal domain

Wnts are lipid-modified morphogens that play critical roles in development principally through engagement of Frizzled receptors. Wnt has a two-domain structure, resembling a "hand" with "thumb" and "index" fingers. This entry represents the C-terminal Wnt domain PMID:22653731.

GO Diversity

Unique GO annotations
794 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
1113 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 1
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 1
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 14
Function
Unique EC:
Unique GO: 794
Taxonomy
Unique Species: 1113