S100 Family: 3.30.200.20.8.1.1.1
Representative domain: 3bu3A01
Classification Lineage (3.30.200.20.8.1.1.1)
Summary of Non-Redundant Representatives
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S100 Count Entries in S100 Family 3.30.200.20.8.1.1.1 (11)
| CATH Level | CATH code | Domain ID | Keywords | Thumbnail |
|---|---|---|---|---|
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3.30.200.20.8.1.1.1.1 | 3bu3A01 | protein autophosphorylation, positive regulation of protein kinase B signaling cascade, positive regulation of protein phosphorylation, insulin-like growth factor I binding, transformation of host cell by virus, positive regulation of glucose import, caveola, positive regulation of DNA replication, insulin receptor signaling pathway, Receptor protein-tyrosine kinase., insulin receptor activity, G-protein coupled receptor protein signaling pathway, peptidyl-tyrosine phosphorylation, activation of MAPK activity, positive regulation of glycolysis, positive regulation of mitosis, Homo sapiens, SH2 domain binding, positive regulation of MAPKKK cascade, positive regulation of cell proliferation, heart morphogenesis, positive regulation of respiratory burst, regulation of embryonic development, positive regulation of nitric oxide biosynthetic process, positive regulation of cell migration, regulation of gene-specific transcription, PTB domain binding, insulin binding, protein heterotetramerization, insulin-like growth factor II binding, Insulin receptor, GTP binding, microsome, insulin receptor substrate binding, positive regulation of glycogen biosynthetic process, positive regulation of developmental growth, activation of protein kinase B activity, ATP binding, phosphoinositide 3-kinase binding, insulin receptor complex, receptor signaling protein tyrosine kinase activity, insulin-like growth factor receptor binding, glucose homeostasis | |
|
3.30.200.20.8.1.1.1.2 | 3bu6A01 | positive regulation of mitosis, positive regulation of glycolysis, positive regulation of cell proliferation, Homo sapiens, SH2 domain binding, positive regulation of MAPKKK cascade, G-protein coupled receptor protein signaling pathway, Receptor protein-tyrosine kinase., insulin receptor activity, peptidyl-tyrosine phosphorylation, activation of MAPK activity, positive regulation of glucose import, positive regulation of DNA replication, caveola, insulin receptor signaling pathway, positive regulation of protein phosphorylation, positive regulation of protein kinase B signaling cascade, protein autophosphorylation, transformation of host cell by virus, insulin-like growth factor I binding, phosphoinositide 3-kinase binding, insulin receptor complex, ATP binding, receptor signaling protein tyrosine kinase activity, glucose homeostasis, insulin-like growth factor receptor binding, GTP binding, positive regulation of glycogen biosynthetic process, microsome, insulin receptor substrate binding, Insulin receptor, activation of protein kinase B activity, positive regulation of developmental growth, positive regulation of cell migration, positive regulation of nitric oxide biosynthetic process, protein heterotetramerization, insulin binding, insulin-like growth factor II binding, regulation of gene-specific transcription, PTB domain binding, regulation of embryonic development, positive regulation of respiratory burst, heart morphogenesis | |
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3.30.200.20.8.1.1.1.3 | 1p14A01 | receptor signaling protein tyrosine kinase activity, insulin receptor complex, ATP binding, phosphoinositide 3-kinase binding, glucose homeostasis, insulin-like growth factor receptor binding, positive regulation of glycogen biosynthetic process, insulin receptor substrate binding, microsome, GTP binding, Insulin receptor, activation of protein kinase B activity, positive regulation of developmental growth, positive regulation of cell migration, positive regulation of nitric oxide biosynthetic process, insulin-like growth factor II binding, insulin binding, protein heterotetramerization, PTB domain binding, regulation of gene-specific transcription, regulation of embryonic development, positive regulation of respiratory burst, heart morphogenesis, positive regulation of mitosis, positive regulation of glycolysis, positive regulation of cell proliferation, Homo sapiens, SH2 domain binding, positive regulation of MAPKKK cascade, G-protein coupled receptor protein signaling pathway, insulin receptor activity, Receptor protein-tyrosine kinase., activation of MAPK activity, peptidyl-tyrosine phosphorylation, positive regulation of DNA replication, caveola, positive regulation of glucose import, insulin receptor signaling pathway, positive regulation of protein phosphorylation, positive regulation of protein kinase B signaling cascade, protein autophosphorylation, transformation of host cell by virus, insulin-like growth factor I binding | |
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3.30.200.20.8.1.1.1.4 | 3eknA01 | positive regulation of DNA replication, caveola, positive regulation of glucose import, insulin receptor signaling pathway, protein autophosphorylation, positive regulation of protein phosphorylation, positive regulation of protein kinase B signaling cascade, insulin-like growth factor I binding, transformation of host cell by virus, positive regulation of glycolysis, positive regulation of mitosis, Homo sapiens, SH2 domain binding, positive regulation of MAPKKK cascade, positive regulation of cell proliferation, insulin receptor activity, Receptor protein-tyrosine kinase., G-protein coupled receptor protein signaling pathway, activation of MAPK activity, peptidyl-tyrosine phosphorylation, positive regulation of nitric oxide biosynthetic process, positive regulation of cell migration, PTB domain binding, regulation of gene-specific transcription, insulin-like growth factor II binding, protein heterotetramerization, insulin binding, heart morphogenesis, regulation of embryonic development, positive regulation of respiratory burst, receptor signaling protein tyrosine kinase activity, ATP binding, phosphoinositide 3-kinase binding, insulin receptor complex, insulin-like growth factor receptor binding, glucose homeostasis, Insulin receptor, positive regulation of glycogen biosynthetic process, insulin receptor substrate binding, microsome, GTP binding, positive regulation of developmental growth, activation of protein kinase B activity | |
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3.30.200.20.8.1.1.1.5 | 3bu5A01 | protein autophosphorylation, positive regulation of protein kinase B signaling cascade, positive regulation of protein phosphorylation, insulin-like growth factor I binding, transformation of host cell by virus, caveola, positive regulation of DNA replication, positive regulation of glucose import, insulin receptor signaling pathway, insulin receptor activity, Receptor protein-tyrosine kinase., G-protein coupled receptor protein signaling pathway, activation of MAPK activity, peptidyl-tyrosine phosphorylation, positive regulation of glycolysis, positive regulation of mitosis, Homo sapiens, positive regulation of MAPKKK cascade, SH2 domain binding, positive regulation of cell proliferation, heart morphogenesis, regulation of embryonic development, positive regulation of respiratory burst, positive regulation of nitric oxide biosynthetic process, positive regulation of cell migration, PTB domain binding, regulation of gene-specific transcription, insulin-like growth factor II binding, protein heterotetramerization, insulin binding, Insulin receptor, positive regulation of glycogen biosynthetic process, insulin receptor substrate binding, microsome, GTP binding, positive regulation of developmental growth, activation of protein kinase B activity, receptor signaling protein tyrosine kinase activity, phosphoinositide 3-kinase binding, insulin receptor complex, ATP binding, insulin-like growth factor receptor binding, glucose homeostasis | |
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3.30.200.20.8.1.1.1.6 | 3ekkA01 | positive regulation of respiratory burst, regulation of embryonic development, heart morphogenesis, positive regulation of cell migration, positive regulation of nitric oxide biosynthetic process, insulin-like growth factor II binding, protein heterotetramerization, insulin binding, PTB domain binding, regulation of gene-specific transcription, positive regulation of glycogen biosynthetic process, insulin receptor substrate binding, microsome, GTP binding, Insulin receptor, activation of protein kinase B activity, positive regulation of developmental growth, receptor signaling protein tyrosine kinase activity, ATP binding, insulin receptor complex, phosphoinositide 3-kinase binding, glucose homeostasis, insulin-like growth factor receptor binding, positive regulation of protein phosphorylation, positive regulation of protein kinase B signaling cascade, protein autophosphorylation, transformation of host cell by virus, insulin-like growth factor I binding, positive regulation of DNA replication, caveola, positive regulation of glucose import, insulin receptor signaling pathway, G-protein coupled receptor protein signaling pathway, insulin receptor activity, Receptor protein-tyrosine kinase., activation of MAPK activity, peptidyl-tyrosine phosphorylation, positive regulation of mitosis, positive regulation of glycolysis, positive regulation of cell proliferation, Homo sapiens, SH2 domain binding, positive regulation of MAPKKK cascade | |
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3.30.200.20.8.1.1.1.7 | 2b4sB01 | receptor signaling protein tyrosine kinase activity, ATP binding, phosphoinositide 3-kinase binding, insulin receptor complex, glucose homeostasis, insulin-like growth factor receptor binding, microsome, insulin receptor substrate binding, positive regulation of glycogen biosynthetic process, GTP binding, Insulin receptor, activation of protein kinase B activity, positive regulation of developmental growth, positive regulation of cell migration, positive regulation of nitric oxide biosynthetic process, insulin-like growth factor II binding, protein heterotetramerization, insulin binding, PTB domain binding, regulation of gene-specific transcription, regulation of embryonic development, positive regulation of respiratory burst, heart morphogenesis, positive regulation of mitosis, positive regulation of glycolysis, positive regulation of cell proliferation, Homo sapiens, positive regulation of MAPKKK cascade, SH2 domain binding, G-protein coupled receptor protein signaling pathway, insulin receptor activity, Receptor protein-tyrosine kinase., activation of MAPK activity, peptidyl-tyrosine phosphorylation, positive regulation of DNA replication, caveola, positive regulation of glucose import, insulin receptor signaling pathway, positive regulation of protein phosphorylation, positive regulation of protein kinase B signaling cascade, protein autophosphorylation, transformation of host cell by virus, insulin-like growth factor I binding | |
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3.30.200.20.8.1.1.1.8 | 2b4sD01 | positive regulation of cell migration, positive regulation of nitric oxide biosynthetic process, insulin-like growth factor II binding, insulin binding, protein heterotetramerization, PTB domain binding, regulation of gene-specific transcription, regulation of embryonic development, positive regulation of respiratory burst, heart morphogenesis, receptor signaling protein tyrosine kinase activity, phosphoinositide 3-kinase binding, insulin receptor complex, ATP binding, glucose homeostasis, insulin-like growth factor receptor binding, positive regulation of glycogen biosynthetic process, insulin receptor substrate binding, microsome, GTP binding, Insulin receptor, activation of protein kinase B activity, positive regulation of developmental growth, positive regulation of DNA replication, caveola, positive regulation of glucose import, insulin receptor signaling pathway, positive regulation of protein phosphorylation, positive regulation of protein kinase B signaling cascade, protein autophosphorylation, transformation of host cell by virus, insulin-like growth factor I binding, positive regulation of mitosis, positive regulation of glycolysis, positive regulation of cell proliferation, Homo sapiens, SH2 domain binding, positive regulation of MAPKKK cascade, G-protein coupled receptor protein signaling pathway, insulin receptor activity, Receptor protein-tyrosine kinase., activation of MAPK activity, peptidyl-tyrosine phosphorylation | |
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3.30.200.20.8.1.1.1.9 | 1rqqA01 | regulation of embryonic development, positive regulation of respiratory burst, heart morphogenesis, positive regulation of cell migration, positive regulation of nitric oxide biosynthetic process, protein heterotetramerization, insulin binding, insulin-like growth factor II binding, regulation of gene-specific transcription, PTB domain binding, GTP binding, positive regulation of glycogen biosynthetic process, insulin receptor substrate binding, microsome, Insulin receptor, activation of protein kinase B activity, positive regulation of developmental growth, ATP binding, phosphoinositide 3-kinase binding, insulin receptor complex, receptor signaling protein tyrosine kinase activity, glucose homeostasis, insulin-like growth factor receptor binding, positive regulation of protein phosphorylation, positive regulation of protein kinase B signaling cascade, protein autophosphorylation, transformation of host cell by virus, insulin-like growth factor I binding, positive regulation of glucose import, caveola, positive regulation of DNA replication, insulin receptor signaling pathway, G-protein coupled receptor protein signaling pathway, Receptor protein-tyrosine kinase., insulin receptor activity, peptidyl-tyrosine phosphorylation, activation of MAPK activity, positive regulation of mitosis, positive regulation of glycolysis, positive regulation of cell proliferation, Homo sapiens, SH2 domain binding, positive regulation of MAPKKK cascade | |
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3.30.200.20.8.1.1.1.10 | 1rqqB01 | protein heterotetramerization, insulin binding, insulin-like growth factor II binding, regulation of gene-specific transcription, PTB domain binding, positive regulation of cell migration, positive regulation of nitric oxide biosynthetic process, positive regulation of respiratory burst, regulation of embryonic development, heart morphogenesis, glucose homeostasis, insulin-like growth factor receptor binding, phosphoinositide 3-kinase binding, ATP binding, insulin receptor complex, receptor signaling protein tyrosine kinase activity, activation of protein kinase B activity, positive regulation of developmental growth, GTP binding, insulin receptor substrate binding, positive regulation of glycogen biosynthetic process, microsome, Insulin receptor, insulin receptor signaling pathway, positive regulation of glucose import, caveola, positive regulation of DNA replication, transformation of host cell by virus, insulin-like growth factor I binding, positive regulation of protein kinase B signaling cascade, positive regulation of protein phosphorylation, protein autophosphorylation, positive regulation of cell proliferation, Homo sapiens, positive regulation of MAPKKK cascade, SH2 domain binding, positive regulation of mitosis, positive regulation of glycolysis, peptidyl-tyrosine phosphorylation, activation of MAPK activity, G-protein coupled receptor protein signaling pathway, Receptor protein-tyrosine kinase., insulin receptor activity | |
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3.30.200.20.8.1.1.1.11 | 2auhA01 | receptor signaling protein tyrosine kinase activity, phosphoinositide 3-kinase binding, insulin receptor complex, ATP binding, insulin-like growth factor receptor binding, glucose homeostasis, Insulin receptor, insulin receptor substrate binding, positive regulation of glycogen biosynthetic process, microsome, GTP binding, positive regulation of developmental growth, activation of protein kinase B activity, positive regulation of nitric oxide biosynthetic process, positive regulation of cell migration, PTB domain binding, regulation of gene-specific transcription, insulin-like growth factor II binding, insulin binding, protein heterotetramerization, heart morphogenesis, regulation of embryonic development, positive regulation of respiratory burst, positive regulation of glycolysis, positive regulation of mitosis, Homo sapiens, positive regulation of MAPKKK cascade, SH2 domain binding, positive regulation of cell proliferation, insulin receptor activity, Receptor protein-tyrosine kinase., G-protein coupled receptor protein signaling pathway, activation of MAPK activity, peptidyl-tyrosine phosphorylation, positive regulation of DNA replication, caveola, positive regulation of glucose import, insulin receptor signaling pathway, protein autophosphorylation, positive regulation of protein kinase B signaling cascade, positive regulation of protein phosphorylation, insulin-like growth factor I binding, transformation of host cell by virus |
The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
- Multiple alignments for each functional family
- Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
- Detailed functional information on diversity and conservation within Functional families
- Multi-domain architectures