S100 Family: 3.30.200.20.15.1.1.1
Representative domain: 1opjA01
Classification Lineage (3.30.200.20.15.1.1.1)
Summary of Non-Redundant Representatives
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|---|---|---|---|---|---|---|---|---|
| - | - | - | - | - | - | - | - | 24 |
S100 Count Entries in S100 Family 3.30.200.20.15.1.1.1 (24)
| CATH Level | CATH code | Domain ID | Keywords | Thumbnail |
|---|---|---|---|---|
|
3.30.200.20.15.1.1.1.1 | 1opjA01 | protein domain specific binding, peptidyl-tyrosine phosphorylation, Mus musculus, Non-specific protein-tyrosine kinase., magnesium ion binding, Tyrosine-protein kinase ABL1, manganese ion binding, actin cytoskeleton organization, ATP binding, nucleus, regulation of cell cycle | |
|
3.30.200.20.15.1.1.1.2 | 1opjB01 | Mus musculus, peptidyl-tyrosine phosphorylation, protein domain specific binding, magnesium ion binding, Non-specific protein-tyrosine kinase., ATP binding, actin cytoskeleton organization, Tyrosine-protein kinase ABL1, manganese ion binding, nucleus, regulation of cell cycle | |
|
3.30.200.20.15.1.1.1.3 | 2hziA01 | Chronic myeloid leukemia, Axon guidance, positive regulation of oxidoreductase activity, ATP binding, manganese ion binding, Tyrosine-protein kinase ABL1, perinuclear region of cytoplasm, magnesium ion binding, protein C-terminus binding, Cell cycle, Pathogenic Escherichia coli infection, DNA damage response, signal transduction resulting in induction of apoptosis, regulation of transcription involved in S phase of mitotic cell cycle, Pathways in cancer, ErbB signaling pathway, Viral myocarditis, Non-specific protein-tyrosine kinase., mismatch repair, Homo sapiens, proto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2], Neurotrophin signaling pathway, peptidyl-tyrosine phosphorylation, nucleolus | |
|
3.30.200.20.15.1.1.1.4 | 2hziB01 | Homo sapiens, proto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2], Neurotrophin signaling pathway, nucleolus, peptidyl-tyrosine phosphorylation, protein C-terminus binding, magnesium ion binding, Cell cycle, DNA damage response, signal transduction resulting in induction of apoptosis, Pathogenic Escherichia coli infection, regulation of transcription involved in S phase of mitotic cell cycle, ErbB signaling pathway, Viral myocarditis, Pathways in cancer, Non-specific protein-tyrosine kinase., mismatch repair, positive regulation of oxidoreductase activity, ATP binding, manganese ion binding, Tyrosine-protein kinase ABL1, perinuclear region of cytoplasm, Chronic myeloid leukemia, Axon guidance | |
|
3.30.200.20.15.1.1.1.5 | 2hiwA01 | proto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2], Homo sapiens, peptidyl-tyrosine phosphorylation, nucleolus, Neurotrophin signaling pathway, magnesium ion binding, protein C-terminus binding, Pathogenic Escherichia coli infection, DNA damage response, signal transduction resulting in induction of apoptosis, Cell cycle, Pathways in cancer, ErbB signaling pathway, Viral myocarditis, regulation of transcription involved in S phase of mitotic cell cycle, mismatch repair, Non-specific protein-tyrosine kinase., positive regulation of oxidoreductase activity, ATP binding, Tyrosine-protein kinase ABL1, perinuclear region of cytoplasm, manganese ion binding, Chronic myeloid leukemia, Axon guidance | |
|
3.30.200.20.15.1.1.1.6 | 2hiwB01 | positive regulation of oxidoreductase activity, ATP binding, manganese ion binding, Tyrosine-protein kinase ABL1, perinuclear region of cytoplasm, Chronic myeloid leukemia, Axon guidance, Homo sapiens, proto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2], Neurotrophin signaling pathway, peptidyl-tyrosine phosphorylation, nucleolus, magnesium ion binding, protein C-terminus binding, Cell cycle, Pathogenic Escherichia coli infection, DNA damage response, signal transduction resulting in induction of apoptosis, regulation of transcription involved in S phase of mitotic cell cycle, Pathways in cancer, ErbB signaling pathway, Viral myocarditis, Non-specific protein-tyrosine kinase., mismatch repair | |
|
3.30.200.20.15.1.1.1.7 | 1iepA01 | regulation of cell cycle, nucleus, manganese ion binding, Tyrosine-protein kinase ABL1, actin cytoskeleton organization, ATP binding, Non-specific protein-tyrosine kinase., magnesium ion binding, protein domain specific binding, peptidyl-tyrosine phosphorylation, Mus musculus | |
|
3.30.200.20.15.1.1.1.8 | 1iepB01 | protein domain specific binding, peptidyl-tyrosine phosphorylation, Mus musculus, Non-specific protein-tyrosine kinase., magnesium ion binding, manganese ion binding, Tyrosine-protein kinase ABL1, actin cytoskeleton organization, ATP binding, regulation of cell cycle, nucleus | |
|
3.30.200.20.15.1.1.1.9 | 2e2bA01 | Axon guidance, Chronic myeloid leukemia, ATP binding, positive regulation of oxidoreductase activity, manganese ion binding, Tyrosine-protein kinase ABL1, perinuclear region of cytoplasm, Cell cycle, Pathogenic Escherichia coli infection, DNA damage response, signal transduction resulting in induction of apoptosis, protein C-terminus binding, magnesium ion binding, Non-specific protein-tyrosine kinase., mismatch repair, regulation of transcription involved in S phase of mitotic cell cycle, Pathways in cancer, ErbB signaling pathway, Viral myocarditis, Homo sapiens, proto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2], Neurotrophin signaling pathway, peptidyl-tyrosine phosphorylation, nucleolus | |
|
3.30.200.20.15.1.1.1.10 | 2e2bB01 | Axon guidance, Chronic myeloid leukemia, manganese ion binding, Tyrosine-protein kinase ABL1, perinuclear region of cytoplasm, ATP binding, positive regulation of oxidoreductase activity, Non-specific protein-tyrosine kinase., mismatch repair, regulation of transcription involved in S phase of mitotic cell cycle, ErbB signaling pathway, Viral myocarditis, Pathways in cancer, Cell cycle, DNA damage response, signal transduction resulting in induction of apoptosis, Pathogenic Escherichia coli infection, magnesium ion binding, protein C-terminus binding, Neurotrophin signaling pathway, nucleolus, peptidyl-tyrosine phosphorylation, Homo sapiens, proto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2] | |
|
3.30.200.20.15.1.1.1.11 | 1fpuA01 | ATP binding, actin cytoskeleton organization, Tyrosine-protein kinase ABL1, manganese ion binding, nucleus, regulation of cell cycle, Mus musculus, peptidyl-tyrosine phosphorylation, protein domain specific binding, magnesium ion binding, Non-specific protein-tyrosine kinase. | |
|
3.30.200.20.15.1.1.1.12 | 1fpuB01 | nucleus, regulation of cell cycle, ATP binding, Tyrosine-protein kinase ABL1, manganese ion binding, actin cytoskeleton organization, magnesium ion binding, Non-specific protein-tyrosine kinase., protein domain specific binding, peptidyl-tyrosine phosphorylation, Mus musculus | |
|
3.30.200.20.15.1.1.1.13 | 2gqgA01 | nucleolus, peptidyl-tyrosine phosphorylation, Neurotrophin signaling pathway, proto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2], Homo sapiens, ErbB signaling pathway, Viral myocarditis, Pathways in cancer, regulation of transcription involved in S phase of mitotic cell cycle, mismatch repair, Non-specific protein-tyrosine kinase., magnesium ion binding, protein C-terminus binding, DNA damage response, signal transduction resulting in induction of apoptosis, Pathogenic Escherichia coli infection, Cell cycle, Tyrosine-protein kinase ABL1, perinuclear region of cytoplasm, manganese ion binding, positive regulation of oxidoreductase activity, ATP binding, Chronic myeloid leukemia, Axon guidance | |
|
3.30.200.20.15.1.1.1.14 | 2gqgB01 | Chronic myeloid leukemia, Axon guidance, Tyrosine-protein kinase ABL1, perinuclear region of cytoplasm, manganese ion binding, positive regulation of oxidoreductase activity, ATP binding, Pathways in cancer, Viral myocarditis, ErbB signaling pathway, regulation of transcription involved in S phase of mitotic cell cycle, mismatch repair, Non-specific protein-tyrosine kinase., protein C-terminus binding, magnesium ion binding, Pathogenic Escherichia coli infection, DNA damage response, signal transduction resulting in induction of apoptosis, Cell cycle, peptidyl-tyrosine phosphorylation, nucleolus, Neurotrophin signaling pathway, proto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2], Homo sapiens | |
|
3.30.200.20.15.1.1.1.15 | 2fo0A03 | Axon guidance, Chronic myeloid leukemia, ATP binding, positive regulation of oxidoreductase activity, Tyrosine-protein kinase ABL1, perinuclear region of cytoplasm, manganese ion binding, Pathogenic Escherichia coli infection, DNA damage response, signal transduction resulting in induction of apoptosis, Cell cycle, protein C-terminus binding, magnesium ion binding, mismatch repair, Non-specific protein-tyrosine kinase., Pathways in cancer, Viral myocarditis, ErbB signaling pathway, regulation of transcription involved in S phase of mitotic cell cycle, proto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2], Homo sapiens, peptidyl-tyrosine phosphorylation, nucleolus, Neurotrophin signaling pathway | |
|
3.30.200.20.15.1.1.1.16 | 3cs9B01 | positive regulation of oxidoreductase activity, ATP binding, manganese ion binding, Tyrosine-protein kinase ABL1, perinuclear region of cytoplasm, Chronic myeloid leukemia, Axon guidance, Homo sapiens, proto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2], Neurotrophin signaling pathway, nucleolus, peptidyl-tyrosine phosphorylation, magnesium ion binding, protein C-terminus binding, Cell cycle, DNA damage response, signal transduction resulting in induction of apoptosis, Pathogenic Escherichia coli infection, regulation of transcription involved in S phase of mitotic cell cycle, Viral myocarditis, ErbB signaling pathway, Pathways in cancer, Non-specific protein-tyrosine kinase., mismatch repair | |
|
3.30.200.20.15.1.1.1.17 | 3cs9A01 | Neurotrophin signaling pathway, nucleolus, peptidyl-tyrosine phosphorylation, Homo sapiens, proto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2], regulation of transcription involved in S phase of mitotic cell cycle, Viral myocarditis, ErbB signaling pathway, Pathways in cancer, Non-specific protein-tyrosine kinase., mismatch repair, magnesium ion binding, protein C-terminus binding, Cell cycle, DNA damage response, signal transduction resulting in induction of apoptosis, Pathogenic Escherichia coli infection, manganese ion binding, Tyrosine-protein kinase ABL1, perinuclear region of cytoplasm, positive regulation of oxidoreductase activity, ATP binding, Chronic myeloid leukemia, Axon guidance | |
|
3.30.200.20.15.1.1.1.18 | 3cs9C01 | Axon guidance, Chronic myeloid leukemia, Tyrosine-protein kinase ABL1, perinuclear region of cytoplasm, manganese ion binding, ATP binding, positive regulation of oxidoreductase activity, mismatch repair, Non-specific protein-tyrosine kinase., Pathways in cancer, ErbB signaling pathway, Viral myocarditis, regulation of transcription involved in S phase of mitotic cell cycle, Pathogenic Escherichia coli infection, DNA damage response, signal transduction resulting in induction of apoptosis, Cell cycle, magnesium ion binding, protein C-terminus binding, peptidyl-tyrosine phosphorylation, nucleolus, Neurotrophin signaling pathway, proto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2], Homo sapiens | |
|
3.30.200.20.15.1.1.1.19 | 3cs9D01 | Neurotrophin signaling pathway, nucleolus, peptidyl-tyrosine phosphorylation, Homo sapiens, proto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2], Non-specific protein-tyrosine kinase., mismatch repair, regulation of transcription involved in S phase of mitotic cell cycle, Viral myocarditis, ErbB signaling pathway, Pathways in cancer, Cell cycle, DNA damage response, signal transduction resulting in induction of apoptosis, Pathogenic Escherichia coli infection, protein C-terminus binding, magnesium ion binding, manganese ion binding, Tyrosine-protein kinase ABL1, perinuclear region of cytoplasm, ATP binding, positive regulation of oxidoreductase activity, Axon guidance, Chronic myeloid leukemia | |
|
3.30.200.20.15.1.1.1.20 | 2hz0B01 | ATP binding, positive regulation of oxidoreductase activity, manganese ion binding, Tyrosine-protein kinase ABL1, perinuclear region of cytoplasm, Axon guidance, Chronic myeloid leukemia, Homo sapiens, proto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2], Neurotrophin signaling pathway, peptidyl-tyrosine phosphorylation, nucleolus, Cell cycle, Pathogenic Escherichia coli infection, DNA damage response, signal transduction resulting in induction of apoptosis, magnesium ion binding, protein C-terminus binding, Non-specific protein-tyrosine kinase., mismatch repair, regulation of transcription involved in S phase of mitotic cell cycle, Pathways in cancer, ErbB signaling pathway, Viral myocarditis | |
|
3.30.200.20.15.1.1.1.21 | 1m52A01 | nucleus, regulation of cell cycle, ATP binding, actin cytoskeleton organization, Tyrosine-protein kinase ABL1, manganese ion binding, magnesium ion binding, Non-specific protein-tyrosine kinase., Mus musculus, peptidyl-tyrosine phosphorylation, protein domain specific binding | |
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3.30.200.20.15.1.1.1.22 | 1m52B01 | nucleus, regulation of cell cycle, ATP binding, Tyrosine-protein kinase ABL1, manganese ion binding, actin cytoskeleton organization, magnesium ion binding, Non-specific protein-tyrosine kinase., protein domain specific binding, peptidyl-tyrosine phosphorylation, Mus musculus | |
|
3.30.200.20.15.1.1.1.23 | 2hznA01 | nucleus, regulation of cell cycle, Tyrosine-protein kinase ABL1, manganese ion binding, actin cytoskeleton organization, ATP binding, Non-specific protein-tyrosine kinase., magnesium ion binding, peptidyl-tyrosine phosphorylation, protein domain specific binding, Mus musculus | |
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3.30.200.20.15.1.1.1.24 | 1oplB02 | Chronic myeloid leukemia, Axon guidance, positive regulation of oxidoreductase activity, ATP binding, manganese ion binding, Tyrosine-protein kinase ABL1, perinuclear region of cytoplasm, protein C-terminus binding, magnesium ion binding, Cell cycle, Pathogenic Escherichia coli infection, DNA damage response, signal transduction resulting in induction of apoptosis, regulation of transcription involved in S phase of mitotic cell cycle, Pathways in cancer, ErbB signaling pathway, Viral myocarditis, Non-specific protein-tyrosine kinase., mismatch repair, Homo sapiens, proto-oncogene tyrosine-protein kinase ABL1 [EC:2.7.10.2], Neurotrophin signaling pathway, peptidyl-tyrosine phosphorylation, nucleolus |
The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
- Multiple alignments for each functional family
- Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
- Detailed functional information on diversity and conservation within Functional families
- Multi-domain architectures