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CATH Superfamily 3.20.180.20

Dynein motor heavy chain, linker domain, subdomain 3

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was named:

"
Dynein heavy chain, N-terminal domain 2
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Dynein motor heavy chain, linker domain, subdomain 3

Dyneins are microtubule-based AAA+ motor complexes that power ciliary beating, cell division, cell migration and intracellular transportPMID:22398446 . The 380kDa motor unit of dynein belongs to the AAA class of chaperone-like ATPases PMID:11250194. The motor domain comprises the AAA+ ring and three additional structural units: the linker, stalk/strut (both of which are major functional units of the heavy chain) and C sequence. This entry represents subdomain 3 of the linker PMID:22398446. PMID:11250194 PMID:22398446

GO Diversity

Unique GO annotations
207 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
1378 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 12
Domain clusters (>95% seq id): 2
Domain clusters (>35% seq id): 2
Unique PDBs: 6
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 49
Function
Unique EC:
Unique GO: 207
Taxonomy
Unique Species: 1378
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