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CATH Superfamily 3.10.490.20

Dynein motor C sequence, barrel region

The name of this superfamily has been modified since the most recent official CATH+ release (v4_4_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Dynein motor C sequence, barrel region

Dyneins are microtubule-based AAA+ motor complexes that power ciliary beating, cell division, cell migration and intracellular transport. The motor domain comprises the AAA+ ring and three additional structural units: the linker, stalk/strut (both of which are major functional units of the heavy chain) and C sequence. The C sequence exists as a complex structure comprising six alpha-helices and an incomplete six-stranded antiparallel beta-barrel. The shape of the C sequence is distinctively flat, spreading over the alpha-submodules of AAA1, AAA5 and AAA6. This entry represents the barrel region of the C sequence PMID:22398446.

GO Diversity

Unique GO annotations
175 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
845 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 4
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 2
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 42
Function
Unique EC:
Unique GO: 175
Taxonomy
Unique Species: 845
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