S100 Family: 3.10.390.10.2.1.1.1

Molscript image for 1mr1D00
Representative domain: 1mr1D00
PDB coordinates for domain 1mr1D00

Classification Lineage (3.10.390.10.2.1.1.1)

CATH CodeLevel DescriptionLinks
3 Alpha Beta
3.10 Roll
3.10.390 SAND domain
3.10.390.10 SAND domain Gene3D
3.10.390.10.2
3.10.390.10.2.1
3.10.390.10.2.1.1
3.10.390.10.2.1.1.1

Summary of Non-Redundant Representatives
- - - - - - - - 2

S100 Count Entries in S100 Family 3.10.390.10.2.1.1.1 (2)

CATH Level CATH code Domain ID Keywords Thumbnail
3.10.390.10.2.1.1.1.1 1mr1D00 transcription corepressor activity, negative regulation of Schwann cell proliferation, zinc ion binding, negative regulation of activin receptor signaling pathway, SMAD binding, negative regulation of BMP signaling pathway, negative regulation of transcription from RNA polymerase II promoter, protein heterotrimerization, positive regulation of DNA binding, SMAD protein signal transduction, ubiquitin protein ligase binding, myotube differentiation, protein kinase binding, negative regulation of osteoblast differentiation, Homo sapiens, negative regulation of transforming growth factor beta receptor signaling pathway, PML body, Ski oncogene, protein domain specific binding, protein homotrimerization, repressing transcription factor binding Molscript image for 1mr1D00
3.10.390.10.2.1.1.1.2 1mr1C00 protein homotrimerization, repressing transcription factor binding, Ski oncogene, protein domain specific binding, PML body, Homo sapiens, negative regulation of transforming growth factor beta receptor signaling pathway, negative regulation of osteoblast differentiation, protein kinase binding, myotube differentiation, ubiquitin protein ligase binding, SMAD protein signal transduction, negative regulation of transcription from RNA polymerase II promoter, protein heterotrimerization, positive regulation of DNA binding, negative regulation of BMP signaling pathway, SMAD binding, transcription corepressor activity, negative regulation of Schwann cell proliferation, zinc ion binding, negative regulation of activin receptor signaling pathway Molscript image for 1mr1C00

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
  • Multiple alignments for each functional family
  • Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
  • Detailed functional information on diversity and conservation within Functional families
  • Multi-domain architectures
In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages:
http://gene3d.biochem.ucl.ac.uk/superfamily/?accession=3.10.390.10.2.1.1.1