S100 Family: 3.10.200.10.1.1.1.1

Representative domain: 3ks3A00

Classification Lineage (3.10.200.10.1.1.1.1)

CATH Code	Level Description	Links
3	Alpha Beta
3.10	Roll
3.10.200	Carbonic Anhydrase II
3.10.200.10	Carbonic Anhydrase II	Gene3D
3.10.200.10.1
3.10.200.10.1.1
3.10.200.10.1.1.1
3.10.200.10.1.1.1.1

Summary of Non-Redundant Representatives


-	-	-	-	-	-	-	-	161

Non-Redundant Representatives (161)
Functional Families
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What is a Non-Redundant Representative?

CATH is a tree-like organisation of nodes that begins with the class node (i.e. the first branch-point of the tree) and ends with the domain nodes (i.e. the leaves of the tree). Each node below the class have a parent that they belong to, e.g. the parent of the H level (Homologous superfamily) is the T (Topology). Additionally, each node above the domains have child nodes that belong to them, e.g. the child nodes of a given H (Homologous superfamily) level are the S35 families (domains clustered at > 35% sequence identity).

S100 Count Entries in S100 Family 3.10.200.10.1.1.1.1 (161)

CATH code	Domain ID	Keywords
3.10.200.10.1.1.1.1.1	3ks3A00	cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism
3.10.200.10.1.1.1.1.2	3k34A00	Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., Carbonic anhydrase 2, apical part of cell, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, zinc ion binding, cytoplasm, nucleus
3.10.200.10.1.1.1.1.3	1lugA00	Carbonic anhydrase 2, apical part of cell, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., zinc ion binding, cytoplasm, nucleus, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation
3.10.200.10.1.1.1.1.4	2iliA00	Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, nucleus, cytoplasm, zinc ion binding, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, apical part of cell, Carbonic anhydrase 2
3.10.200.10.1.1.1.1.5	3d92A00	carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, zinc ion binding, cytoplasm, nucleus, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., Carbonic anhydrase 2, apical part of cell
3.10.200.10.1.1.1.1.6	3d93A00	Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm
3.10.200.10.1.1.1.1.7	3hs4A00	carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, zinc ion binding, cytoplasm, nucleus, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., Carbonic anhydrase 2, apical part of cell
3.10.200.10.1.1.1.1.8	2wegA00	Carbonic anhydrase 2, apical part of cell, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., zinc ion binding, cytoplasm, nucleus, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation
3.10.200.10.1.1.1.1.9	2eu2A00	Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.10	3gz0A00	apical part of cell, Carbonic anhydrase 2, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, nucleus, zinc ion binding, cytoplasm, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation
3.10.200.10.1.1.1.1.11	2weoA00	Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm
3.10.200.10.1.1.1.1.12	3ibuA00	carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2
3.10.200.10.1.1.1.1.13	2qo8A00	cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism
3.10.200.10.1.1.1.1.14	3hljA00	carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2
3.10.200.10.1.1.1.1.15	2aw1A00	Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.16	2gd8A00	nucleus, cytoplasm, zinc ion binding, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, apical part of cell, Carbonic anhydrase 2, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens
3.10.200.10.1.1.1.1.17	2qp6A00	carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, Carbonic anhydrase 2, apical part of cell, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, cytoplasm, zinc ion binding, nucleus
3.10.200.10.1.1.1.1.18	2wejA00	nucleus, zinc ion binding, cytoplasm, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, apical part of cell, Carbonic anhydrase 2, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion
3.10.200.10.1.1.1.1.19	1oq5A00	apical part of cell, Carbonic anhydrase 2, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, nucleus, zinc ion binding, cytoplasm, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation
3.10.200.10.1.1.1.1.20	3dd0A00	Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.21	2wd2A00	Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm
3.10.200.10.1.1.1.1.22	2ax2A00	Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, apical part of cell, Carbonic anhydrase 2, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, nucleus, cytoplasm, zinc ion binding
3.10.200.10.1.1.1.1.23	1zfqA00	zinc ion binding, cytoplasm, nucleus, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, Carbonic anhydrase 2, apical part of cell, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase.
3.10.200.10.1.1.1.1.24	2hl4A00	Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, apical part of cell, Carbonic anhydrase 2, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, nucleus, cytoplasm, zinc ion binding
3.10.200.10.1.1.1.1.25	2hncA00	Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, nucleus, cytoplasm, zinc ion binding, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, apical part of cell, Carbonic anhydrase 2
3.10.200.10.1.1.1.1.26	1zfkA00	nucleus, cytoplasm, zinc ion binding, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, apical part of cell, Carbonic anhydrase 2, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens
3.10.200.10.1.1.1.1.27	3iblA00	Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.28	2vvaX00	nucleus, cytoplasm, zinc ion binding, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, apical part of cell, Carbonic anhydrase 2, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens
3.10.200.10.1.1.1.1.29	1cilA00	cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism
3.10.200.10.1.1.1.1.30	2eu3A00	Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, apical part of cell, Carbonic anhydrase 2, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, nucleus, cytoplasm, zinc ion binding
3.10.200.10.1.1.1.1.31	2fmgA00	apical part of cell, Carbonic anhydrase 2, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, nucleus, cytoplasm, zinc ion binding, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.32	2fmzA00	Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, nucleus, cytoplasm, zinc ion binding, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, apical part of cell, Carbonic anhydrase 2
3.10.200.10.1.1.1.1.33	2osfA00	carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, Carbonic anhydrase 2, apical part of cell, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, cytoplasm, zinc ion binding, nucleus
3.10.200.10.1.1.1.1.34	2qoaA00	Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, cytoplasm, zinc ion binding, nucleus, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, Carbonic anhydrase 2, apical part of cell
3.10.200.10.1.1.1.1.35	3dazA00	nucleus, zinc ion binding, cytoplasm, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, apical part of cell, Carbonic anhydrase 2, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion
3.10.200.10.1.1.1.1.36	2osmA00	apical part of cell, Carbonic anhydrase 2, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, nucleus, cytoplasm, zinc ion binding, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.37	2pouA00	Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.38	2x7sA00	Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.39	1zgeA00	zinc ion binding, cytoplasm, nucleus, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, Carbonic anhydrase 2, apical part of cell, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase.
3.10.200.10.1.1.1.1.40	3d9zA00	carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, Carbonic anhydrase 2, apical part of cell, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, cytoplasm, zinc ion binding, nucleus
3.10.200.10.1.1.1.1.41	1z9yA00	apical part of cell, Carbonic anhydrase 2, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, nucleus, zinc ion binding, cytoplasm, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation
3.10.200.10.1.1.1.1.42	2vvbX00	Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, apical part of cell, Carbonic anhydrase 2, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, nucleus, cytoplasm, zinc ion binding
3.10.200.10.1.1.1.1.43	3igpA00	Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.44	2q1bA00	carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, zinc ion binding, cytoplasm, nucleus, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., Carbonic anhydrase 2, apical part of cell
3.10.200.10.1.1.1.1.45	3cyuA00	carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, Carbonic anhydrase 2, apical part of cell, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, cytoplasm, zinc ion binding, nucleus
3.10.200.10.1.1.1.1.46	3d8wA00	Carbonic anhydrase 2, apical part of cell, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., zinc ion binding, cytoplasm, nucleus, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation
3.10.200.10.1.1.1.1.47	3hkqA00	cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism
3.10.200.10.1.1.1.1.48	2f14A00	cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism
3.10.200.10.1.1.1.1.49	3c7pA00	nucleus, cytoplasm, zinc ion binding, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, apical part of cell, Carbonic anhydrase 2, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens
3.10.200.10.1.1.1.1.50	1zgfA00	Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, apical part of cell, Carbonic anhydrase 2, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, nucleus, cytoplasm, zinc ion binding
3.10.200.10.1.1.1.1.51	3efiA00
3.10.200.10.1.1.1.1.52	2powA00	nucleus, cytoplasm, zinc ion binding, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, apical part of cell, Carbonic anhydrase 2, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens
3.10.200.10.1.1.1.1.53	1xq0A00	Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, apical part of cell, Carbonic anhydrase 2, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, nucleus, cytoplasm, zinc ion binding
3.10.200.10.1.1.1.1.54	2hd6A00	Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, cytoplasm, zinc ion binding, nucleus, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, Carbonic anhydrase 2, apical part of cell
3.10.200.10.1.1.1.1.55	2wd3A00	Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm
3.10.200.10.1.1.1.1.56	3hknA00	Carbonic anhydrase 2, apical part of cell, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., zinc ion binding, cytoplasm, nucleus, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation
3.10.200.10.1.1.1.1.57	3hkuA00	Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., Carbonic anhydrase 2, apical part of cell, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, zinc ion binding, cytoplasm, nucleus
3.10.200.10.1.1.1.1.58	3ffpX00	nucleus, cytoplasm, zinc ion binding, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, apical part of cell, Carbonic anhydrase 2, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens
3.10.200.10.1.1.1.1.59	1g52A00	carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, Carbonic anhydrase 2, apical part of cell, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, cytoplasm, zinc ion binding, nucleus
3.10.200.10.1.1.1.1.60	1rayA00	Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., Carbonic anhydrase 2, apical part of cell, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, zinc ion binding, cytoplasm, nucleus
3.10.200.10.1.1.1.1.61	1rzbA00	nucleus, cytoplasm, zinc ion binding, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, apical part of cell, Carbonic anhydrase 2, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens
3.10.200.10.1.1.1.1.62	3cajA00	nucleus, zinc ion binding, cytoplasm, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, apical part of cell, Carbonic anhydrase 2, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion
3.10.200.10.1.1.1.1.63	1xegA00	apical part of cell, Carbonic anhydrase 2, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, nucleus, cytoplasm, zinc ion binding, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.64	3eftA00	nucleus, zinc ion binding, cytoplasm, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, apical part of cell, Carbonic anhydrase 2, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion
3.10.200.10.1.1.1.1.65	1bv3A00	carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, zinc ion binding, cytoplasm, nucleus, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., Carbonic anhydrase 2, apical part of cell
3.10.200.10.1.1.1.1.66	3betA00	Carbonic anhydrase 2, apical part of cell, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., zinc ion binding, cytoplasm, nucleus, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation
3.10.200.10.1.1.1.1.67	1g54A00	Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., Carbonic anhydrase 2, apical part of cell, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, zinc ion binding, cytoplasm, nucleus
3.10.200.10.1.1.1.1.68	3b4fA00	Carbonic anhydrase 2, apical part of cell, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., zinc ion binding, cytoplasm, nucleus, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation
3.10.200.10.1.1.1.1.69	2x7tA00	Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.70	1cnxA00	apical part of cell, Carbonic anhydrase 2, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, nucleus, cytoplasm, zinc ion binding, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.71	2ca2A00	Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm
3.10.200.10.1.1.1.1.72	2h15A00	apical part of cell, Carbonic anhydrase 2, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, nucleus, zinc ion binding, cytoplasm, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation
3.10.200.10.1.1.1.1.73	2hkkA00	Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm
3.10.200.10.1.1.1.1.74	3dd8A00	Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., Carbonic anhydrase 2, apical part of cell, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, zinc ion binding, cytoplasm, nucleus
3.10.200.10.1.1.1.1.75	3f4xA00	Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm
3.10.200.10.1.1.1.1.76	1cahA00	carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, Carbonic anhydrase 2, apical part of cell, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, cytoplasm, zinc ion binding, nucleus
3.10.200.10.1.1.1.1.77	1f2wA00	carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2
3.10.200.10.1.1.1.1.78	2q1qA00	apical part of cell, Carbonic anhydrase 2, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, nucleus, cytoplasm, zinc ion binding, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.79	3bl0A00	carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, Carbonic anhydrase 2, apical part of cell, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, cytoplasm, zinc ion binding, nucleus
3.10.200.10.1.1.1.1.80	3k7kA00	apical part of cell, Carbonic anhydrase 2, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, nucleus, cytoplasm, zinc ion binding, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.81	1bcdA00	cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism
3.10.200.10.1.1.1.1.82	1razA00	Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, apical part of cell, Carbonic anhydrase 2, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, nucleus, cytoplasm, zinc ion binding
3.10.200.10.1.1.1.1.83	1rzaA00	carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, zinc ion binding, cytoplasm, nucleus, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., Carbonic anhydrase 2, apical part of cell
3.10.200.10.1.1.1.1.84	1rzcA00	carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, Carbonic anhydrase 2, apical part of cell, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, cytoplasm, zinc ion binding, nucleus
3.10.200.10.1.1.1.1.85	1rzdA00	Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, nucleus, cytoplasm, zinc ion binding, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, apical part of cell, Carbonic anhydrase 2
3.10.200.10.1.1.1.1.86	1rzeA00	nucleus, cytoplasm, zinc ion binding, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, apical part of cell, Carbonic anhydrase 2, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens
3.10.200.10.1.1.1.1.87	3ibiA00	cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism
3.10.200.10.1.1.1.1.88	2q38A00	Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., Carbonic anhydrase 2, apical part of cell, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, zinc ion binding, cytoplasm, nucleus
3.10.200.10.1.1.1.1.89	1i8zA00	Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, nucleus, cytoplasm, zinc ion binding, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, apical part of cell, Carbonic anhydrase 2
3.10.200.10.1.1.1.1.90	1if4A00	Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm
3.10.200.10.1.1.1.1.91	1g53A00	Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm
3.10.200.10.1.1.1.1.92	1if8A00	apical part of cell, Carbonic anhydrase 2, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, nucleus, cytoplasm, zinc ion binding, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.93	1ttmA00	Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, apical part of cell, Carbonic anhydrase 2, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, nucleus, cytoplasm, zinc ion binding
3.10.200.10.1.1.1.1.94	3k2fA00	carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, zinc ion binding, cytoplasm, nucleus, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., Carbonic anhydrase 2, apical part of cell
3.10.200.10.1.1.1.1.95	1ca2A00	Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, cytoplasm, zinc ion binding, nucleus, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, Carbonic anhydrase 2, apical part of cell
3.10.200.10.1.1.1.1.96	1cnwA00	Carbonic anhydrase 2, apical part of cell, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., zinc ion binding, cytoplasm, nucleus, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation
3.10.200.10.1.1.1.1.97	3ca2A00	Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm
3.10.200.10.1.1.1.1.98	3f8eA00	zinc ion binding, cytoplasm, nucleus, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, Carbonic anhydrase 2, apical part of cell, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase.
3.10.200.10.1.1.1.1.99	3ieoA00	apical part of cell, Carbonic anhydrase 2, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, nucleus, cytoplasm, zinc ion binding, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.100	1if7A00	carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2
3.10.200.10.1.1.1.1.101	1avnA00	cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism
3.10.200.10.1.1.1.1.102	2abeA00	Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, cytoplasm, zinc ion binding, nucleus, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, Carbonic anhydrase 2, apical part of cell
3.10.200.10.1.1.1.1.103	2gehA00	carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2
3.10.200.10.1.1.1.1.104	1am6A00	zinc ion binding, cytoplasm, nucleus, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, Carbonic anhydrase 2, apical part of cell, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase.
3.10.200.10.1.1.1.1.105	1i90A00	Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm
3.10.200.10.1.1.1.1.106	1i91A00	apical part of cell, Carbonic anhydrase 2, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, nucleus, zinc ion binding, cytoplasm, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation
3.10.200.10.1.1.1.1.107	1if5A00	carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2
3.10.200.10.1.1.1.1.108	1if9A00	cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism
3.10.200.10.1.1.1.1.109	1t9nA00	carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2
3.10.200.10.1.1.1.1.110	1tb0X00	Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, cytoplasm, zinc ion binding, nucleus, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, Carbonic anhydrase 2, apical part of cell
3.10.200.10.1.1.1.1.111	1tbtX00	Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.112	1te3X00	nucleus, cytoplasm, zinc ion binding, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, apical part of cell, Carbonic anhydrase 2, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens
3.10.200.10.1.1.1.1.113	1teqX00	Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, cytoplasm, zinc ion binding, nucleus, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, Carbonic anhydrase 2, apical part of cell
3.10.200.10.1.1.1.1.114	1teuX00	carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, Carbonic anhydrase 2, apical part of cell, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, cytoplasm, zinc ion binding, nucleus
3.10.200.10.1.1.1.1.115	1ze8A00	cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism
3.10.200.10.1.1.1.1.116	2ez7A00	zinc ion binding, cytoplasm, nucleus, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, Carbonic anhydrase 2, apical part of cell, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase.
3.10.200.10.1.1.1.1.117	3kkxA00	zinc ion binding, cytoplasm, nucleus, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, Carbonic anhydrase 2, apical part of cell, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase.
3.10.200.10.1.1.1.1.118	1xpzA00	apical part of cell, Carbonic anhydrase 2, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, nucleus, cytoplasm, zinc ion binding, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.119	1g1dA00	Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., Carbonic anhydrase 2, apical part of cell, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, zinc ion binding, cytoplasm, nucleus
3.10.200.10.1.1.1.1.120	1cimA00	Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., Carbonic anhydrase 2, apical part of cell, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, zinc ion binding, cytoplasm, nucleus
3.10.200.10.1.1.1.1.121	1cinA00	Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, nucleus, cytoplasm, zinc ion binding, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, apical part of cell, Carbonic anhydrase 2
3.10.200.10.1.1.1.1.122	2o4zA00	carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, zinc ion binding, cytoplasm, nucleus, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., Carbonic anhydrase 2, apical part of cell
3.10.200.10.1.1.1.1.123	3bl1A00	carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, Carbonic anhydrase 2, apical part of cell, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, cytoplasm, zinc ion binding, nucleus
3.10.200.10.1.1.1.1.124	3hfpA00	Carbonic anhydrase 2, apical part of cell, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., zinc ion binding, cytoplasm, nucleus, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation
3.10.200.10.1.1.1.1.125	1bn1A00	Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.126	1bn4A00	Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., Carbonic anhydrase 2, apical part of cell, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, zinc ion binding, cytoplasm, nucleus
3.10.200.10.1.1.1.1.127	1if6A00	nucleus, cytoplasm, zinc ion binding, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, apical part of cell, Carbonic anhydrase 2, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens
3.10.200.10.1.1.1.1.128	1oklA00	nucleus, cytoplasm, zinc ion binding, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, apical part of cell, Carbonic anhydrase 2, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens
3.10.200.10.1.1.1.1.129	4ca2A00	Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, cytoplasm, zinc ion binding, nucleus, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, Carbonic anhydrase 2, apical part of cell
3.10.200.10.1.1.1.1.130	1cayA00	Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., Carbonic anhydrase 2, apical part of cell, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, zinc ion binding, cytoplasm, nucleus
3.10.200.10.1.1.1.1.131	1eouA00	apical part of cell, Carbonic anhydrase 2, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, nucleus, zinc ion binding, cytoplasm, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation
3.10.200.10.1.1.1.1.132	2hocA00	nucleus, cytoplasm, zinc ion binding, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, apical part of cell, Carbonic anhydrase 2, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens
3.10.200.10.1.1.1.1.133	2wehA00	nucleus, zinc ion binding, cytoplasm, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, apical part of cell, Carbonic anhydrase 2, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion
3.10.200.10.1.1.1.1.134	2x7uA00	cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism
3.10.200.10.1.1.1.1.135	1bntA00	Carbonic anhydrase 2, apical part of cell, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase., zinc ion binding, cytoplasm, nucleus, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation
3.10.200.10.1.1.1.1.136	1bnuA00	Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, nucleus, cytoplasm, zinc ion binding, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, apical part of cell, Carbonic anhydrase 2
3.10.200.10.1.1.1.1.137	4cacA00	Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.138	5cacA00	Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, apical part of cell, Carbonic anhydrase 2, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, nucleus, cytoplasm, zinc ion binding
3.10.200.10.1.1.1.1.139	1bn3A00	cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism
3.10.200.10.1.1.1.1.140	1okmA00	carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, Carbonic anhydrase 2, apical part of cell, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, cytoplasm, zinc ion binding, nucleus
3.10.200.10.1.1.1.1.141	1xevA00	Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, nucleus, cytoplasm, zinc ion binding, Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, apical part of cell, Carbonic anhydrase 2
3.10.200.10.1.1.1.1.142	1xevD00	carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2
3.10.200.10.1.1.1.1.143	3ibnA00	apical part of cell, Carbonic anhydrase 2, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, nucleus, zinc ion binding, cytoplasm, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation
3.10.200.10.1.1.1.1.144	1xevB00	Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm
3.10.200.10.1.1.1.1.145	1xevC00	Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, apical part of cell, Carbonic anhydrase 2, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, nucleus, cytoplasm, zinc ion binding
3.10.200.10.1.1.1.1.146	1a42A00	Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm
3.10.200.10.1.1.1.1.147	1bnwA00	apical part of cell, Carbonic anhydrase 2, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, nucleus, zinc ion binding, cytoplasm, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation
3.10.200.10.1.1.1.1.148	1kwrA00	carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, nucleus, zinc ion binding, cytoplasm, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, apical part of cell, Carbonic anhydrase 2
3.10.200.10.1.1.1.1.149	1cnyA00	zinc ion binding, cytoplasm, nucleus, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, Carbonic anhydrase 2, apical part of cell, Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Nitrogen metabolism, Carbonate dehydratase.
3.10.200.10.1.1.1.1.150	1bnnA00	Carbonate dehydratase., Nitrogen metabolism, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, apical part of cell, Carbonic anhydrase 2, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, nucleus, cytoplasm, zinc ion binding
3.10.200.10.1.1.1.1.151	1ca3A00	nucleus, zinc ion binding, cytoplasm, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, apical part of cell, Carbonic anhydrase 2, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion
3.10.200.10.1.1.1.1.152	1hcaA00	nucleus, zinc ion binding, cytoplasm, carbonate dehydratase activity, Proximal tubule bicarbonate reclamation, apical part of cell, Carbonic anhydrase 2, Nitrogen metabolism, Carbonate dehydratase., Homo sapiens, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion
3.10.200.10.1.1.1.1.153	3hktA00	Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, cytoplasm, zinc ion binding, nucleus, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, Carbonic anhydrase 2, apical part of cell
3.10.200.10.1.1.1.1.154	1bnqA00	cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism
3.10.200.10.1.1.1.1.155	1oknA00	carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, Carbonic anhydrase 2, apical part of cell, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, cytoplasm, zinc ion binding, nucleus
3.10.200.10.1.1.1.1.156	1bnvA00	Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.157	1bnmA00	Carbonic anhydrase 2, apical part of cell, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, cytoplasm, zinc ion binding, nucleus, Proximal tubule bicarbonate reclamation, carbonate dehydratase activity
3.10.200.10.1.1.1.1.158	1kwqA00	Proximal tubule bicarbonate reclamation, carbonate dehydratase activity, cytoplasm, zinc ion binding, nucleus, carbonic anhydrase [EC:4.2.1.1], Collecting duct acid secretion, Homo sapiens, Carbonate dehydratase., Nitrogen metabolism, Carbonic anhydrase 2, apical part of cell
3.10.200.10.1.1.1.1.159	1g6vA00	carbonic anhydrase [EC:4.2.1.1], Bos taurus, Nitrogen metabolism, Carbonate dehydratase., Carbonic anhydrase 2
3.10.200.10.1.1.1.1.160	3ks1A00
3.10.200.10.1.1.1.1.161	3ks1B00

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:

Multiple alignments for each functional family
Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
Detailed functional information on diversity and conservation within Functional families
Multi-domain architectures

In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages:

http://gene3d.biochem.ucl.ac.uk/superfamily/?accession=3.10.200.10.1.1.1.1

What is a Non-Redundant Representative?

Why can't I have a multiple structural alignment of the whole superfamily?

The simple answer is that some of the larger superfamilies in CATH comprise relatives which are very structurally diverse, having different secondary structure embellishments. Attempting to provide a global alignment of all domains in the superfamily would result in poor quality alignments. As a result, structural alignments in CATH are generated by first clustering together the structures that have at least some recognisable structural similarity using a normalised RMSD score (SIMAX = RMSDxNumber of residues in the largest domain/number of aligned residues) less than a given cutoff.

What is an Close Structural Cluster?

A Close Structural Cluster describes a cluster of two or more CATH domains that have been grouped together due to their close structural similarity (SIMAX score < 5Å where SIMAX = RMSD x Number of residues in the larger domain/number of aligned residues).

What is a Distant Structural Cluster?

A Distant Structural Cluster describes a cluster of two or CATH domains that have been grouped together with a more relaxed structural similarity threshold to investigate more distant evolutionary similarities (SIMAX score < 5Å where SIMAX = RMSD x Number of residues in the larger domain/number of aligned residues).

What is a Structural Neighbour?

The term "structural neighbour" is used here to describe two CATH domains that share a degree of structural similarity. The SSAP algorithm is used to calculate this similarity and works by generating a structure-based pairwise alignment of the two domains then scoring this alignment using a RMSD score which has been normalised by the length of the larger domain divided by the number of aligned residues (SIMAX).

S100 Family: 3.10.200.10.1.1.1.1

Classification Lineage (3.10.200.10.1.1.1.1)

Summary of Non-Redundant Representatives

What is a Non-Redundant Representative?

S100 Count Entries in S100 Family 3.10.200.10.1.1.1.1 (161)

What is a Non-Redundant Representative?

Why can't I have a multiple structural alignment of the whole superfamily?

What is an Close Structural Cluster?

What is a Distant Structural Cluster?

What is a Structural Neighbour?

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