The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was: waiting to be named.

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: Beta-grasp domain

This superfamily represents a domain with a beta-grasp fold and a core structure consisting of beta(2)-alpha-beta(2), which is similar to that found in ubiquitin PMID:16859499. Domains with this type of structure are found in the 2Fe-2S ferredoxin family (including putidaredoxin and adrenodoxin) PMID:15755454, the 2Fe-2S ferredoxin-related family (including aldehyde reductase, and xanthine dehydrogenase) PMID:11713686, the TGS family (including threonyl-tRNA synthetase) PMID:10319817 and the MoaD/ThiS family (including molybdopterin, and thiamine biosynthesis sulphur carrier protein) PMID:16388576.

PMID:16859499 PMID:15755454 PMID:11713686 PMID:10319817 PMID:16388576

GO Diversity

Unique GO annotations
321 Unique GO terms

EC Diversity

Unique EC annotations
33 Unique EC terms

Species Diversity

Unique species annotations
23474 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 520
Domain clusters (>95% seq id): 108
Domain clusters (>35% seq id): 48
Unique PDBs: 310
Alignments
Structural Clusters (5A): 6
Structural Clusters (9A): 2
FunFam Clusters: 116
Function
Unique EC: 33
Unique GO: 321
Taxonomy
Unique Species: 23474