S100 Family: 2.80.10.50.8.1.1.1
Representative domain: 1pwaA00
Classification Lineage (2.80.10.50.8.1.1.1)
| CATH Code | Level Description | Links |
|---|---|---|
 2
| Mainly Beta | |
 2.80
| Trefoil | |
 2.80.10
| Trefoil (Acidic Fibroblast Growth Factor, subunit A) | |
 2.80.10.50
| Gene3D | |
 2.80.10.50.8
| ||
 2.80.10.50.8.1
| ||
 2.80.10.50.8.1.1
| ||
 2.80.10.50.8.1.1.1
|
Summary of Non-Redundant Representatives
| | | | | | | |  |
|---|---|---|---|---|---|---|---|---|
| - | - | - | - | - | - | - | - | 3 |
S100 Count Entries in S100 Family 2.80.10.50.8.1.1.1 (3)
| CATH Level | CATH code | Domain ID | Keywords | Thumbnail |
|---|---|---|---|---|
|
2.80.10.50.8.1.1.1.1 | 1pwaA00 | Pathways in cancer, Regulation of actin cytoskeleton, Fibroblast growth factor 19, positive regulation of glucose import, positive regulation of JNK cascade, MAPK signaling pathway, Melanoma, positive regulation of ERK1 and ERK2 cascade, fibroblast growth factor receptor signaling pathway, positive regulation of cell proliferation, Homo sapiens, fibroblast growth factor receptor binding, fibroblast growth factor, nervous system development, negative regulation of bile acid biosynthetic process | |
|
2.80.10.50.8.1.1.1.2 | 2p23A00 | fibroblast growth factor, nervous system development, negative regulation of bile acid biosynthetic process, Melanoma, positive regulation of ERK1 and ERK2 cascade, fibroblast growth factor receptor signaling pathway, positive regulation of cell proliferation, Homo sapiens, fibroblast growth factor receptor binding, Pathways in cancer, Regulation of actin cytoskeleton, Fibroblast growth factor 19, positive regulation of glucose import, positive regulation of JNK cascade, MAPK signaling pathway | |
|
2.80.10.50.8.1.1.1.3 | 2p23B00 | positive regulation of cell proliferation, Homo sapiens, fibroblast growth factor receptor binding, Melanoma, positive regulation of ERK1 and ERK2 cascade, fibroblast growth factor receptor signaling pathway, positive regulation of glucose import, positive regulation of JNK cascade, MAPK signaling pathway, Pathways in cancer, Regulation of actin cytoskeleton, Fibroblast growth factor 19, fibroblast growth factor, nervous system development, negative regulation of bile acid biosynthetic process |
The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
- Multiple alignments for each functional family
- Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
- Detailed functional information on diversity and conservation within Functional families
- Multi-domain architectures