S100 Family: 2.60.40.820.1.1.1.1

Molscript image for 1h6fA00
Representative domain: 1h6fA00
PDB coordinates for domain 1h6fA00

Classification Lineage (2.60.40.820.1.1.1.1)

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.60 Sandwich
2.60.40 Immunoglobulin-like
2.60.40.820 Gene3D
2.60.40.820.1
2.60.40.820.1.1
2.60.40.820.1.1.1
2.60.40.820.1.1.1.1

Summary of Non-Redundant Representatives

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S100 Count Entries in S100 Family 2.60.40.820.1.1.1.1 (2)

CATH Level CATH code Domain ID Keywords Thumbnail
2.60.40.820.1.1.1.1.1 1h6fA00 regulation of transcription from RNA polymerase II promoter, embryonic arm morphogenesis, embryonic digit morphogenesis, RNA polymerase II transcription factor activity, luteinizing hormone secretion, mesoderm morphogenesis, cytoplasm, anterior/posterior axis specification, embryo, negative regulation of myoblast differentiation, nucleus, general transcriptional repressor activity, female genitalia development, positive regulation of cell proliferation, Homo sapiens, follicle-stimulating hormone secretion, skeletal system development, mammary gland development, positive regulation of cell cycle, T-box transcription factor TBX3, male genitalia development, negative regulation of transcription, DNA-dependent, sequence-specific DNA binding, anti-apoptosis, cell aging Molscript image for 1h6fA00
2.60.40.820.1.1.1.1.2 1h6fB00 follicle-stimulating hormone secretion, positive regulation of cell proliferation, Homo sapiens, T-box transcription factor TBX3, skeletal system development, mammary gland development, positive regulation of cell cycle, male genitalia development, sequence-specific DNA binding, cell aging, anti-apoptosis, negative regulation of transcription, DNA-dependent, embryonic digit morphogenesis, embryonic arm morphogenesis, regulation of transcription from RNA polymerase II promoter, luteinizing hormone secretion, RNA polymerase II transcription factor activity, cytoplasm, mesoderm morphogenesis, general transcriptional repressor activity, negative regulation of myoblast differentiation, nucleus, female genitalia development, anterior/posterior axis specification, embryo Molscript image for 1h6fB00

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
  • Multiple alignments for each functional family
  • Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
  • Detailed functional information on diversity and conservation within Functional families
  • Multi-domain architectures
In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages: