S100 Family: 2.60.40.630.1.1.2.1

Molscript image for 1yvlA03
Representative domain: 1yvlA03
PDB coordinates for domain 1yvlA03

Classification Lineage (2.60.40.630.1.1.2.1)

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.60 Sandwich
2.60.40 Immunoglobulin-like
2.60.40.630 Gene3D
2.60.40.630.1
2.60.40.630.1.1
2.60.40.630.1.1.2
2.60.40.630.1.1.2.1

Summary of Non-Redundant Representatives

- - - - - - - - 3

S100 Count Entries in S100 Family 2.60.40.630.1.1.2.1 (3)

CATH Level CATH code Domain ID Keywords Thumbnail
2.60.40.630.1.1.2.1.1 1yvlA03 nucleolus, transcription from RNA polymerase II promoter, sequence-specific DNA binding transcription factor activity, Homo sapiens, Pancreatic cancer, Chemokine signaling pathway, protein binding, Pathways in cancer, Toll-like receptor signaling pathway, Jak-STAT signaling pathway, tyrosine phosphorylation of STAT protein, Leishmaniasis, I-kappaB kinase/NF-kappaB cascade, activation of caspase activity, cytoplasm, Signal transducer and activator of transcription 1-alpha/beta, signal transducer and activator of transcription 1 Molscript image for 1yvlA03
2.60.40.630.1.1.2.1.2 1yvlB03 nucleolus, transcription from RNA polymerase II promoter, sequence-specific DNA binding transcription factor activity, Homo sapiens, Chemokine signaling pathway, Pancreatic cancer, Pathways in cancer, protein binding, Toll-like receptor signaling pathway, Jak-STAT signaling pathway, tyrosine phosphorylation of STAT protein, I-kappaB kinase/NF-kappaB cascade, activation of caspase activity, Leishmaniasis, cytoplasm, signal transducer and activator of transcription 1, Signal transducer and activator of transcription 1-alpha/beta Molscript image for 1yvlB03
2.60.40.630.1.1.2.1.3 1bf5A02 Toll-like receptor signaling pathway, activation of caspase activity, I-kappaB kinase/NF-kappaB cascade, Leishmaniasis, Jak-STAT signaling pathway, tyrosine phosphorylation of STAT protein, signal transducer and activator of transcription 1, Signal transducer and activator of transcription 1-alpha/beta, cytoplasm, nucleolus, transcription from RNA polymerase II promoter, Homo sapiens, Chemokine signaling pathway, Pancreatic cancer, sequence-specific DNA binding transcription factor activity, Pathways in cancer, protein binding Molscript image for 1bf5A02

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
  • Multiple alignments for each functional family
  • Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
  • Detailed functional information on diversity and conservation within Functional families
  • Multi-domain architectures
In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages: