S60 Family: 2.60.40.10.7.1

Molscript image for 1k5nA02
Representative domain: 1k5nA02
PDB coordinates for domain 1k5nA02

Classification Lineage (2.60.40.10.7.1)

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.60 Sandwich
2.60.40 Immunoglobulin-like
2.60.40.10 Immunoglobulins Gene3D
2.60.40.10.7
2.60.40.10.7.1

Summary of Non-Redundant Representatives
- - - - - - 17 32 527

S95 Family Entries in S60 Family 2.60.40.10.7.1 (17)

CATH Level CATH code Representative Domain Representative Keywords Representative Thumbnail Number of Domains
2.60.40.10.7.1.1 1k5nA02 HLA class I histocompatibility antigen, B-27 alpha chainMembrane fractionDefense responseHomo sapiens Molscript image for 1k5nA02 104
2.60.40.10.7.1.2 1lk2A02 Type I diabetes mellitusAutoimmune thyroid diseaseAntigen processing and presentation of exogenous peptide antigen via MHC class IDefense response to bacteriumAllograft rejection Molscript image for 1lk2A02 89
2.60.40.10.7.1.3 1x7qA02 HLA class I histocompatibility antigen, A-11 alpha chainHomo sapiens Molscript image for 1x7qA02 13
2.60.40.10.7.1.4 3d25A02 HLA class I histocompatibility antigen, A-2 alpha chainHomo sapiensProtein binding Molscript image for 3d25A02 183
2.60.40.10.7.1.5 1kjvA02 Molscript image for 1kjvA02 4
2.60.40.10.7.1.6 3ecbA02 Mus musculusExternal side of plasma membraneH-2 class I histocompatibility antigen, D-D alpha chainProtein binding Molscript image for 3ecbA02 7
2.60.40.10.7.1.7 3kyoA02 Type I diabetes mellitusMHC class I receptor activityAutoimmune thyroid diseaseNatural killer cell mediated cytotoxicityCellular defense response Molscript image for 3kyoA02 7
2.60.40.10.7.1.8 1wbxA02 Type I diabetes mellitusAutoimmune thyroid diseaseNatural killer cell mediated cytotoxicityAllograft rejectionH-2 class I histocompatibility antigen, D-B alpha chain Molscript image for 1wbxA02 80
2.60.40.10.7.1.9 1mhcA02 Positive regulation of interferon-gamma productionType I diabetes mellitusPositive regulation of nitric oxide biosynthetic processAutoimmune thyroid diseaseAllograft rejection Molscript image for 1mhcA02 2
2.60.40.10.7.1.10 1nezA02 Mus musculusH-2 class I histocompatibility antigen, TLA(B) alpha chain Molscript image for 1nezA02 1
2.60.40.10.7.1.11 1vgkA02 Mus musculusH-2 class I histocompatibility antigen, K-D alpha chainPositive regulation of T cell mediated cytotoxicityExternal side of plasma membranePeptide antigen binding Molscript image for 1vgkA02 2
2.60.40.10.7.1.12 1k8dA02 Mus musculusH-2 class I histocompatibility antigen, Q7 alpha chain Molscript image for 1k8dA02 1
2.60.40.10.7.1.13 1r3hA02 Mus musculusMHC class I H2-TL-T10-129 mRNA (b haplotype), complete cds Molscript image for 1r3hA02 4
2.60.40.10.7.1.14 3bzeA02 MHC class I receptor activityHLA class I histocompatibility antigen, alpha chain EHomo sapiens Molscript image for 3bzeA02 15
2.60.40.10.7.1.15 1qqdA02 HLA class I histocompatibility antigen, Cw-4 alpha chainHomo sapiens Molscript image for 1qqdA02 4
2.60.40.10.7.1.16 1c16A02 Type I diabetes mellitusAutoimmune thyroid diseaseAllograft rejectionAntigen processing and presentationEndocytosis Molscript image for 1c16A02 6
2.60.40.10.7.1.17 1zs8A02 Mus musculusMajor histocompatibility complex class Ib M10.5 Molscript image for 1zs8A02 5

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
  • Multiple alignments for each functional family
  • Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
  • Detailed functional information on diversity and conservation within Functional families
  • Multi-domain architectures
In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages:
http://gene3d.biochem.ucl.ac.uk/superfamily/?accession=2.60.40.10.7.1