S100 Family: 2.40.10.10.45.1.1.1

Molscript image for 2o8tA01
Representative domain: 2o8tA01
PDB coordinates for domain 2o8tA01

Classification Lineage (2.40.10.10.45.1.1.1)

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.40 Beta Barrel
2.40.10 Thrombin, subunit H
2.40.10.10 Trypsin-like serine proteases Gene3D
2.40.10.10.45
2.40.10.10.45.1
2.40.10.10.45.1.1
2.40.10.10.45.1.1.1

Summary of Non-Redundant Representatives

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S100 Count Entries in S100 Family 2.40.10.10.45.1.1.1 (5)

CATH Level CATH code Domain ID Keywords Thumbnail
2.40.10.10.45.1.1.1.1 2o8tA01 cell surface, proteolysis, regulation of smooth muscle cell migration, regulation of cell adhesion mediated by integrin, U-plasminogen activator., Urokinase-type plasminogen activator, regulation of receptor activity, Homo sapiens, extracellular space, signal transduction, chemotaxis Molscript image for 2o8tA01
2.40.10.10.45.1.1.1.2 2nwnA01 Homo sapiens, chemotaxis, signal transduction, extracellular space, U-plasminogen activator., regulation of receptor activity, Urokinase-type plasminogen activator, regulation of cell adhesion mediated by integrin, proteolysis, regulation of smooth muscle cell migration, cell surface Molscript image for 2nwnA01
2.40.10.10.45.1.1.1.3 3kgpA01 cell surface, proteolysis, regulation of smooth muscle cell migration, regulation of cell adhesion mediated by integrin, U-plasminogen activator., Urokinase-type plasminogen activator, regulation of receptor activity, Homo sapiens, signal transduction, extracellular space, chemotaxis Molscript image for 3kgpA01
2.40.10.10.45.1.1.1.4 3khvA01 regulation of cell adhesion mediated by integrin, cell surface, regulation of smooth muscle cell migration, proteolysis, Homo sapiens, chemotaxis, signal transduction, extracellular space, U-plasminogen activator., Urokinase-type plasminogen activator, regulation of receptor activity Molscript image for 3khvA01
2.40.10.10.45.1.1.1.5 3kidU01 cell surface, proteolysis, regulation of smooth muscle cell migration, regulation of cell adhesion mediated by integrin, U-plasminogen activator., Urokinase-type plasminogen activator, regulation of receptor activity, Homo sapiens, chemotaxis, signal transduction, extracellular space Molscript image for 3kidU01

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
  • Multiple alignments for each functional family
  • Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
  • Detailed functional information on diversity and conservation within Functional families
  • Multi-domain architectures
In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages: