S100 Family: 2.30.30.40.20.1.1.1

Molscript image for 1gcqC00
Representative domain: 1gcqC00
PDB coordinates for domain 1gcqC00

Classification Lineage (2.30.30.40.20.1.1.1)

CATH CodeLevel DescriptionLinks
2 Mainly Beta
2.30 Roll
2.30.30 SH3 type barrels.
2.30.30.40 SH3 Domains Gene3D
2.30.30.40.20
2.30.30.40.20.1
2.30.30.40.20.1.1
2.30.30.40.20.1.1.1

Summary of Non-Redundant Representatives

- - - - - - - - 5

S100 Count Entries in S100 Family 2.30.30.40.20.1.1.1 (5)

CATH Level CATH code Domain ID Keywords Thumbnail
2.30.30.40.20.1.1.1.1 1gcqC00 positive regulation of cell adhesion, phagocytosis, Proto-oncogene vav, Mus musculus, regulation of GTPase activity, immune response, T cell differentiation, integrin-mediated signaling pathway, protein binding, Rac guanyl-nucleotide exchange factor activity Molscript image for 1gcqC00
2.30.30.40.20.1.1.1.2 1gcpA00 positive regulation of cell adhesion, Proto-oncogene vav, phagocytosis, Mus musculus, regulation of GTPase activity, immune response, T cell differentiation, protein binding, integrin-mediated signaling pathway, Rac guanyl-nucleotide exchange factor activity Molscript image for 1gcpA00
2.30.30.40.20.1.1.1.3 1gcpC00 Proto-oncogene vav, phagocytosis, positive regulation of cell adhesion, protein binding, integrin-mediated signaling pathway, Rac guanyl-nucleotide exchange factor activity, Mus musculus, regulation of GTPase activity, T cell differentiation, immune response Molscript image for 1gcpC00
2.30.30.40.20.1.1.1.4 1gcpD00 positive regulation of cell adhesion, Proto-oncogene vav, phagocytosis, Mus musculus, regulation of GTPase activity, T cell differentiation, immune response, protein binding, integrin-mediated signaling pathway, Rac guanyl-nucleotide exchange factor activity Molscript image for 1gcpD00
2.30.30.40.20.1.1.1.5 1gcpB00 Rac guanyl-nucleotide exchange factor activity, protein binding, integrin-mediated signaling pathway, immune response, T cell differentiation, Mus musculus, regulation of GTPase activity, Proto-oncogene vav, phagocytosis, positive regulation of cell adhesion Molscript image for 1gcpB00

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
  • Multiple alignments for each functional family
  • Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
  • Detailed functional information on diversity and conservation within Functional families
  • Multi-domain architectures
In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages: