S100 Family: 2.30.29.30.1.1.1.1
Representative domain: 1unqA00
Classification Lineage (2.30.29.30.1.1.1.1)
Summary of Non-Redundant Representatives
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| - | - | - | - | - | - | - | - | 3 |
S100 Count Entries in S100 Family 2.30.29.30.1.1.1.1 (3)
| CATH Level | CATH code | Domain ID | Keywords | Thumbnail |
|---|---|---|---|---|
|
2.30.29.30.1.1.1.1.1 | 1unqA00 | Fc gamma R-mediated phagocytosis, Renal cell carcinoma, Adipocytokine signaling pathway, response to UV-A, positive regulation of glycogen biosynthetic process, positive regulation of establishment of protein localization in plasma membrane, activation-induced cell death of T cells, identical protein binding, Endometrial cancer, VEGF signaling pathway, Apoptosis, Toll-like receptor signaling pathway, plasma membrane, phosphatidylinositol-3,4,5-trisphosphate binding, Chronic myeloid leukemia, insulin-like growth factor receptor signaling pathway, positive regulation of nitric-oxide synthase activity, negative regulation of protein kinase activity, Colorectal cancer, Non-small cell lung cancer, Tight junction, protein import into nucleus, translocation, Progesterone-mediated oocyte maturation, Jak-STAT signaling pathway, response to fluid shear stress, positive regulation of fat cell differentiation, Fc epsilon RI signaling pathway, positive regulation of cell growth, nitric-oxide synthase regulator activity, positive regulation of nitric oxide biosynthetic process, Focal adhesion, B cell receptor signaling pathway, Chagas disease, response to heat, Neurotrophin signaling pathway, Melanoma, positive regulation of cyclin-dependent protein kinase activity involved in G1/S, protein serine/threonine kinase activity, G-protein coupled receptor protein signaling pathway, Homo sapiens, Chemokine signaling pathway, Pancreatic cancer, RAC serine/threonine-protein kinase [EC:2.7.11.1], negative regulation of plasma membrane long-chain fatty acid transport, T cell receptor signaling pathway, ErbB signaling pathway, Glioma, Pathways in cancer, phosphatidylinositol-3,4-bisphosphate binding, protein autophosphorylation, positive regulation of lipid biosynthetic process, Acute myeloid leukemia, RAC-alpha serine/threonine-protein kinase, Prostate cancer, insulin receptor signaling pathway, nitric oxide biosynthetic process, peptidyl-serine phosphorylation, Non-specific serine/threonine protein kinase., negative regulation of fatty acid beta-oxidation, Small cell lung cancer, MAPK signaling pathway, mTOR signaling pathway, Insulin signaling pathway, positive regulation of glucose import | |
|
2.30.29.30.1.1.1.1.2 | 1unpA00 | protein autophosphorylation, positive regulation of lipid biosynthetic process, Acute myeloid leukemia, RAC-alpha serine/threonine-protein kinase, ErbB signaling pathway, Glioma, Pathways in cancer, phosphatidylinositol-3,4-bisphosphate binding, MAPK signaling pathway, mTOR signaling pathway, Insulin signaling pathway, positive regulation of glucose import, Prostate cancer, insulin receptor signaling pathway, nitric oxide biosynthetic process, peptidyl-serine phosphorylation, Non-specific serine/threonine protein kinase., negative regulation of fatty acid beta-oxidation, Small cell lung cancer, positive regulation of cyclin-dependent protein kinase activity involved in G1/S, protein serine/threonine kinase activity, G-protein coupled receptor protein signaling pathway, Neurotrophin signaling pathway, Melanoma, RAC serine/threonine-protein kinase [EC:2.7.11.1], negative regulation of plasma membrane long-chain fatty acid transport, T cell receptor signaling pathway, Homo sapiens, Chemokine signaling pathway, Pancreatic cancer, Tight junction, protein import into nucleus, translocation, Progesterone-mediated oocyte maturation, Jak-STAT signaling pathway, Chronic myeloid leukemia, positive regulation of nitric-oxide synthase activity, negative regulation of protein kinase activity, insulin-like growth factor receptor signaling pathway, Colorectal cancer, Non-small cell lung cancer, positive regulation of nitric oxide biosynthetic process, B cell receptor signaling pathway, Chagas disease, Focal adhesion, response to heat, response to fluid shear stress, positive regulation of fat cell differentiation, Fc epsilon RI signaling pathway, positive regulation of cell growth, nitric-oxide synthase regulator activity, Adipocytokine signaling pathway, response to UV-A, positive regulation of glycogen biosynthetic process, positive regulation of establishment of protein localization in plasma membrane, Fc gamma R-mediated phagocytosis, Renal cell carcinoma, VEGF signaling pathway, Apoptosis, Toll-like receptor signaling pathway, plasma membrane, phosphatidylinositol-3,4,5-trisphosphate binding, activation-induced cell death of T cells, identical protein binding, Endometrial cancer | |
|
2.30.29.30.1.1.1.1.3 | 2uvmA00 | positive regulation of establishment of protein localization in plasma membrane, positive regulation of glycogen biosynthetic process, Renal cell carcinoma, Fc gamma R-mediated phagocytosis, Apoptosis, VEGF signaling pathway, Toll-like receptor signaling pathway, plasma membrane, phosphatidylinositol-3,4,5-trisphosphate binding, identical protein binding, activation-induced cell death of T cells, Endometrial cancer, Tight junction, Progesterone-mediated oocyte maturation, Jak-STAT signaling pathway, protein import into nucleus, translocation, Colorectal cancer, Chronic myeloid leukemia, insulin-like growth factor receptor signaling pathway, negative regulation of protein kinase activity, positive regulation of nitric-oxide synthase activity, Non-small cell lung cancer, positive regulation of nitric oxide biosynthetic process, Focal adhesion, B cell receptor signaling pathway, Chagas disease, response to heat, Fc epsilon RI signaling pathway, response to fluid shear stress, positive regulation of fat cell differentiation, positive regulation of cell growth, nitric-oxide synthase regulator activity, positive regulation of cyclin-dependent protein kinase activity involved in G1/S, G-protein coupled receptor protein signaling pathway, protein serine/threonine kinase activity, Neurotrophin signaling pathway, Melanoma, RAC serine/threonine-protein kinase [EC:2.7.11.1], T cell receptor signaling pathway, negative regulation of plasma membrane long-chain fatty acid transport, Pancreatic cancer, Chemokine signaling pathway, Homo sapiens, protein autophosphorylation, Acute myeloid leukemia, RAC-alpha serine/threonine-protein kinase, positive regulation of lipid biosynthetic process, Glioma, Pathways in cancer, phosphatidylinositol-3,4-bisphosphate binding, ErbB signaling pathway, MAPK signaling pathway, Insulin signaling pathway, positive regulation of glucose import, mTOR signaling pathway, peptidyl-serine phosphorylation, Prostate cancer, insulin receptor signaling pathway, nitric oxide biosynthetic process, Small cell lung cancer, Non-specific serine/threonine protein kinase., negative regulation of fatty acid beta-oxidation, Adipocytokine signaling pathway, response to UV-A |
The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
- Multiple alignments for each functional family
- Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
- Detailed functional information on diversity and conservation within Functional families
- Multi-domain architectures