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CATH Superfamily 1.25.40.770

TAF6, C-terminal HEAT repeat domain

The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
TAF6, C-terminal HEAT repeat domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

Superfamily: TAF6, C-terminal HEAT repeat domain

Structural domains comprising this superfamily share the structure of the C-terminal HEAT repeat-containing C-terminal Domain of TAF6 (TAF6C), which is involved in TFIID TAF6-TAF9 complex formation and modulated by the TAF5 protein. This domain comprises five HEAT repeats that are conserved from yeast to human. HEAT repeats (and the related ARM repeat) are protein/protein interaction motifs that are repeated many times in a wide variety of proteins, forming superhelices that interact extensively with their target proteins PMID:22696218.

GO Diversity

Unique GO annotations
49 Unique GO terms

EC Diversity

Unique EC annotations
0 Unique EC terms

Species Diversity

Unique species annotations
1380 Unique species

Sequence/Structure Diversity

Overview of the sequence / structure diversity of this superfamily compared to other superfamilies in CATH. Click on the chart to view the data in more detail.

Superfamily Summary

A general summary of information for this superfamily.
Structures
Domains: 1
Domain clusters (>95% seq id): 1
Domain clusters (>35% seq id): 1
Unique PDBs: 1
Alignments
Structural Clusters (5A): 1
Structural Clusters (9A): 1
FunFam Clusters: 28
Function
Unique EC:
Unique GO: 49
Taxonomy
Unique Species: 1380