S100 Family: 1.25.40.70.1.1.1.1
Representative domain: 1e8yA03
Classification Lineage (1.25.40.70.1.1.1.1)
Summary of Non-Redundant Representatives
 |  |  |  |  |  |  |  |  |
|---|---|---|---|---|---|---|---|---|
| - | - | - | - | - | - | - | - | 17 |
S100 Count Entries in S100 Family 1.25.40.70.1.1.1.1 (17)
| CATH Level | CATH code | Domain ID | Keywords | Thumbnail |
|---|---|---|---|---|
|
1.25.40.70.1.1.1.1.1 | 1e8yA03 | protein binding, Glioma, Pathways in cancer, Regulation of actin cytoskeleton, ErbB signaling pathway, Inositol phosphate metabolism, Acute myeloid leukemia, Prostate cancer, Small cell lung cancer, Phosphatidylinositol-4,5-bisphosphate 3-kinase., 1-phosphatidylinositol-3-kinase activity, Insulin signaling pathway, mTOR signaling pathway, phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153], Aldosterone-regulated sodium reabsorption, Melanoma, Leukocyte transendothelial migration, Neurotrophin signaling pathway, Type II diabetes mellitus, G-protein coupled receptor protein signaling pathway, Pancreatic cancer, Chemokine signaling pathway, Homo sapiens, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, T cell receptor signaling pathway, Colorectal cancer, Chronic myeloid leukemia, Non-small cell lung cancer, Phosphatidylinositol signaling system, Natural killer cell mediated cytotoxicity, Progesterone-mediated oocyte maturation, Jak-STAT signaling pathway, Fc epsilon RI signaling pathway, B cell receptor signaling pathway, Chagas disease, Focal adhesion, Renal cell carcinoma, Fc gamma R-mediated phagocytosis, Endometrial cancer, VEGF signaling pathway, Apoptosis, Toll-like receptor signaling pathway | |
|
1.25.40.70.1.1.1.1.2 | 1e8zA03 | Endometrial cancer, VEGF signaling pathway, Toll-like receptor signaling pathway, Apoptosis, Renal cell carcinoma, Fc gamma R-mediated phagocytosis, Fc epsilon RI signaling pathway, B cell receptor signaling pathway, Focal adhesion, Chagas disease, Colorectal cancer, Chronic myeloid leukemia, Non-small cell lung cancer, Phosphatidylinositol signaling system, Natural killer cell mediated cytotoxicity, Progesterone-mediated oocyte maturation, Jak-STAT signaling pathway, Chemokine signaling pathway, Pancreatic cancer, Homo sapiens, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, T cell receptor signaling pathway, phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153], Aldosterone-regulated sodium reabsorption, Neurotrophin signaling pathway, Melanoma, Leukocyte transendothelial migration, Type II diabetes mellitus, G-protein coupled receptor protein signaling pathway, Prostate cancer, Small cell lung cancer, Phosphatidylinositol-4,5-bisphosphate 3-kinase., 1-phosphatidylinositol-3-kinase activity, Insulin signaling pathway, mTOR signaling pathway, protein binding, Glioma, Pathways in cancer, ErbB signaling pathway, Regulation of actin cytoskeleton, Inositol phosphate metabolism, Acute myeloid leukemia | |
|
1.25.40.70.1.1.1.1.3 | 3eneA03 | G-protein coupled receptor protein signaling pathway, phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153], Aldosterone-regulated sodium reabsorption, Leukocyte transendothelial migration, Melanoma, Neurotrophin signaling pathway, Type II diabetes mellitus, T cell receptor signaling pathway, Pancreatic cancer, Chemokine signaling pathway, Homo sapiens, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Inositol phosphate metabolism, Acute myeloid leukemia, protein binding, Glioma, Pathways in cancer, ErbB signaling pathway, Regulation of actin cytoskeleton, 1-phosphatidylinositol-3-kinase activity, Insulin signaling pathway, mTOR signaling pathway, Prostate cancer, Small cell lung cancer, Phosphatidylinositol-4,5-bisphosphate 3-kinase., Renal cell carcinoma, Fc gamma R-mediated phagocytosis, Apoptosis, VEGF signaling pathway, Toll-like receptor signaling pathway, Endometrial cancer, Natural killer cell mediated cytotoxicity, Jak-STAT signaling pathway, Progesterone-mediated oocyte maturation, Colorectal cancer, Chronic myeloid leukemia, Non-small cell lung cancer, Phosphatidylinositol signaling system, Chagas disease, B cell receptor signaling pathway, Focal adhesion, Fc epsilon RI signaling pathway | |
|
1.25.40.70.1.1.1.1.4 | 2chxA03 | Chronic myeloid leukemia, Colorectal cancer, Phosphatidylinositol signaling system, Non-small cell lung cancer, Natural killer cell mediated cytotoxicity, Progesterone-mediated oocyte maturation, Jak-STAT signaling pathway, Fc epsilon RI signaling pathway, Focal adhesion, B cell receptor signaling pathway, Chagas disease, Fc gamma R-mediated phagocytosis, Renal cell carcinoma, Endometrial cancer, VEGF signaling pathway, Toll-like receptor signaling pathway, Apoptosis, protein binding, ErbB signaling pathway, Regulation of actin cytoskeleton, Glioma, Pathways in cancer, Inositol phosphate metabolism, Acute myeloid leukemia, Prostate cancer, Phosphatidylinositol-4,5-bisphosphate 3-kinase., Small cell lung cancer, 1-phosphatidylinositol-3-kinase activity, mTOR signaling pathway, Insulin signaling pathway, Neurotrophin signaling pathway, Melanoma, Leukocyte transendothelial migration, phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153], Aldosterone-regulated sodium reabsorption, Type II diabetes mellitus, G-protein coupled receptor protein signaling pathway, Homo sapiens, Chemokine signaling pathway, Pancreatic cancer, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, T cell receptor signaling pathway | |
|
1.25.40.70.1.1.1.1.5 | 2v4lA03 | B cell receptor signaling pathway, Chagas disease, Focal adhesion, Fc epsilon RI signaling pathway, Progesterone-mediated oocyte maturation, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Non-small cell lung cancer, Phosphatidylinositol signaling system, Colorectal cancer, Chronic myeloid leukemia, Toll-like receptor signaling pathway, VEGF signaling pathway, Apoptosis, Endometrial cancer, Renal cell carcinoma, Fc gamma R-mediated phagocytosis, Insulin signaling pathway, mTOR signaling pathway, 1-phosphatidylinositol-3-kinase activity, Small cell lung cancer, Phosphatidylinositol-4,5-bisphosphate 3-kinase., Prostate cancer, Acute myeloid leukemia, Inositol phosphate metabolism, Pathways in cancer, Glioma, ErbB signaling pathway, Regulation of actin cytoskeleton, protein binding, T cell receptor signaling pathway, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Pancreatic cancer, Chemokine signaling pathway, Homo sapiens, G-protein coupled receptor protein signaling pathway, Type II diabetes mellitus, phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153], Aldosterone-regulated sodium reabsorption, Neurotrophin signaling pathway, Leukocyte transendothelial migration, Melanoma | |
|
1.25.40.70.1.1.1.1.6 | 2chwA03 | Fc gamma R-mediated phagocytosis, Renal cell carcinoma, Apoptosis, Toll-like receptor signaling pathway, VEGF signaling pathway, Endometrial cancer, Natural killer cell mediated cytotoxicity, Progesterone-mediated oocyte maturation, Jak-STAT signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Phosphatidylinositol signaling system, Non-small cell lung cancer, Focal adhesion, Chagas disease, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, G-protein coupled receptor protein signaling pathway, Neurotrophin signaling pathway, Leukocyte transendothelial migration, Melanoma, phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153], Aldosterone-regulated sodium reabsorption, Type II diabetes mellitus, T cell receptor signaling pathway, Homo sapiens, Pancreatic cancer, Chemokine signaling pathway, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Inositol phosphate metabolism, Acute myeloid leukemia, protein binding, Regulation of actin cytoskeleton, ErbB signaling pathway, Glioma, Pathways in cancer, 1-phosphatidylinositol-3-kinase activity, mTOR signaling pathway, Insulin signaling pathway, Prostate cancer, Phosphatidylinositol-4,5-bisphosphate 3-kinase., Small cell lung cancer | |
|
1.25.40.70.1.1.1.1.7 | 2chzA03 | Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Chemokine signaling pathway, Pancreatic cancer, Homo sapiens, T cell receptor signaling pathway, Type II diabetes mellitus, phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153], Aldosterone-regulated sodium reabsorption, Melanoma, Neurotrophin signaling pathway, Leukocyte transendothelial migration, G-protein coupled receptor protein signaling pathway, Small cell lung cancer, Phosphatidylinositol-4,5-bisphosphate 3-kinase., Prostate cancer, Insulin signaling pathway, mTOR signaling pathway, 1-phosphatidylinositol-3-kinase activity, Glioma, Pathways in cancer, ErbB signaling pathway, Regulation of actin cytoskeleton, protein binding, Acute myeloid leukemia, Inositol phosphate metabolism, Endometrial cancer, VEGF signaling pathway, Toll-like receptor signaling pathway, Apoptosis, Renal cell carcinoma, Fc gamma R-mediated phagocytosis, Fc epsilon RI signaling pathway, Chagas disease, Focal adhesion, B cell receptor signaling pathway, Non-small cell lung cancer, Phosphatidylinositol signaling system, Colorectal cancer, Chronic myeloid leukemia, Jak-STAT signaling pathway, Progesterone-mediated oocyte maturation, Natural killer cell mediated cytotoxicity | |
|
1.25.40.70.1.1.1.1.8 | 2a5uA03 | T cell receptor signaling pathway, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Homo sapiens, Pancreatic cancer, Chemokine signaling pathway, G-protein coupled receptor protein signaling pathway, Type II diabetes mellitus, Leukocyte transendothelial migration, Melanoma, Neurotrophin signaling pathway, phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153], Aldosterone-regulated sodium reabsorption, mTOR signaling pathway, Insulin signaling pathway, 1-phosphatidylinositol-3-kinase activity, Phosphatidylinositol-4,5-bisphosphate 3-kinase., Small cell lung cancer, Prostate cancer, Acute myeloid leukemia, Inositol phosphate metabolism, ErbB signaling pathway, Regulation of actin cytoskeleton, Pathways in cancer, Glioma, protein binding, Toll-like receptor signaling pathway, Apoptosis, VEGF signaling pathway, Endometrial cancer, Fc gamma R-mediated phagocytosis, Renal cell carcinoma, Focal adhesion, Chagas disease, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Progesterone-mediated oocyte maturation, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Phosphatidylinositol signaling system, Non-small cell lung cancer, Chronic myeloid leukemia, Colorectal cancer | |
|
1.25.40.70.1.1.1.1.9 | 3dbsA03 | 1-phosphatidylinositol-3-kinase activity, mTOR signaling pathway, Insulin signaling pathway, Prostate cancer, Phosphatidylinositol-4,5-bisphosphate 3-kinase., Small cell lung cancer, Inositol phosphate metabolism, Acute myeloid leukemia, protein binding, ErbB signaling pathway, Regulation of actin cytoskeleton, Glioma, Pathways in cancer, T cell receptor signaling pathway, Homo sapiens, Chemokine signaling pathway, Pancreatic cancer, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, G-protein coupled receptor protein signaling pathway, Neurotrophin signaling pathway, Melanoma, Leukocyte transendothelial migration, phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153], Aldosterone-regulated sodium reabsorption, Type II diabetes mellitus, B cell receptor signaling pathway, Focal adhesion, Chagas disease, Fc epsilon RI signaling pathway, Natural killer cell mediated cytotoxicity, Jak-STAT signaling pathway, Progesterone-mediated oocyte maturation, Chronic myeloid leukemia, Colorectal cancer, Phosphatidylinositol signaling system, Non-small cell lung cancer, Toll-like receptor signaling pathway, VEGF signaling pathway, Apoptosis, Endometrial cancer, Fc gamma R-mediated phagocytosis, Renal cell carcinoma | |
|
1.25.40.70.1.1.1.1.10 | 3csfA03 | Fc gamma R-mediated phagocytosis, Renal cell carcinoma, Apoptosis, Toll-like receptor signaling pathway, VEGF signaling pathway, Endometrial cancer, Jak-STAT signaling pathway, Progesterone-mediated oocyte maturation, Natural killer cell mediated cytotoxicity, Phosphatidylinositol signaling system, Non-small cell lung cancer, Chronic myeloid leukemia, Colorectal cancer, B cell receptor signaling pathway, Chagas disease, Focal adhesion, Fc epsilon RI signaling pathway, G-protein coupled receptor protein signaling pathway, Type II diabetes mellitus, Melanoma, Leukocyte transendothelial migration, Neurotrophin signaling pathway, phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153], Aldosterone-regulated sodium reabsorption, T cell receptor signaling pathway, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Homo sapiens, Pancreatic cancer, Chemokine signaling pathway, Acute myeloid leukemia, Inositol phosphate metabolism, ErbB signaling pathway, Regulation of actin cytoskeleton, Glioma, Pathways in cancer, protein binding, mTOR signaling pathway, Insulin signaling pathway, 1-phosphatidylinositol-3-kinase activity, Phosphatidylinositol-4,5-bisphosphate 3-kinase., Small cell lung cancer, Prostate cancer | |
|
1.25.40.70.1.1.1.1.11 | 3dpdA03 | Focal adhesion, B cell receptor signaling pathway, Chagas disease, Fc epsilon RI signaling pathway, Natural killer cell mediated cytotoxicity, Progesterone-mediated oocyte maturation, Jak-STAT signaling pathway, Colorectal cancer, Chronic myeloid leukemia, Non-small cell lung cancer, Phosphatidylinositol signaling system, VEGF signaling pathway, Toll-like receptor signaling pathway, Apoptosis, Endometrial cancer, Renal cell carcinoma, Fc gamma R-mediated phagocytosis, 1-phosphatidylinositol-3-kinase activity, Insulin signaling pathway, mTOR signaling pathway, Prostate cancer, Small cell lung cancer, Phosphatidylinositol-4,5-bisphosphate 3-kinase., Inositol phosphate metabolism, Acute myeloid leukemia, protein binding, Glioma, Pathways in cancer, Regulation of actin cytoskeleton, ErbB signaling pathway, T cell receptor signaling pathway, Chemokine signaling pathway, Pancreatic cancer, Homo sapiens, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, G-protein coupled receptor protein signaling pathway, phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153], Aldosterone-regulated sodium reabsorption, Neurotrophin signaling pathway, Melanoma, Leukocyte transendothelial migration, Type II diabetes mellitus | |
|
1.25.40.70.1.1.1.1.12 | 3l16A03 | Inositol phosphate metabolism, Acute myeloid leukemia, protein binding, Glioma, Pathways in cancer, ErbB signaling pathway, Regulation of actin cytoskeleton, 1-phosphatidylinositol-3-kinase activity, Insulin signaling pathway, mTOR signaling pathway, Prostate cancer, Small cell lung cancer, Phosphatidylinositol-4,5-bisphosphate 3-kinase., G-protein coupled receptor protein signaling pathway, phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153], Aldosterone-regulated sodium reabsorption, Leukocyte transendothelial migration, Melanoma, Neurotrophin signaling pathway, Type II diabetes mellitus, T cell receptor signaling pathway, Pancreatic cancer, Chemokine signaling pathway, Homo sapiens, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Natural killer cell mediated cytotoxicity, Jak-STAT signaling pathway, Progesterone-mediated oocyte maturation, Colorectal cancer, Chronic myeloid leukemia, Non-small cell lung cancer, Phosphatidylinositol signaling system, Chagas disease, Focal adhesion, B cell receptor signaling pathway, Fc epsilon RI signaling pathway, Renal cell carcinoma, Fc gamma R-mediated phagocytosis, VEGF signaling pathway, Toll-like receptor signaling pathway, Apoptosis, Endometrial cancer | |
|
1.25.40.70.1.1.1.1.13 | 2a4zA03 | G-protein coupled receptor protein signaling pathway, Melanoma, Leukocyte transendothelial migration, Neurotrophin signaling pathway, phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153], Aldosterone-regulated sodium reabsorption, Type II diabetes mellitus, T cell receptor signaling pathway, Homo sapiens, Pancreatic cancer, Chemokine signaling pathway, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Inositol phosphate metabolism, Acute myeloid leukemia, protein binding, Regulation of actin cytoskeleton, ErbB signaling pathway, Glioma, Pathways in cancer, 1-phosphatidylinositol-3-kinase activity, mTOR signaling pathway, Insulin signaling pathway, Prostate cancer, Phosphatidylinositol-4,5-bisphosphate 3-kinase., Small cell lung cancer, Fc gamma R-mediated phagocytosis, Renal cell carcinoma, Toll-like receptor signaling pathway, VEGF signaling pathway, Apoptosis, Endometrial cancer, Natural killer cell mediated cytotoxicity, Progesterone-mediated oocyte maturation, Jak-STAT signaling pathway, Chronic myeloid leukemia, Colorectal cancer, Phosphatidylinositol signaling system, Non-small cell lung cancer, B cell receptor signaling pathway, Chagas disease, Focal adhesion, Fc epsilon RI signaling pathway | |
|
1.25.40.70.1.1.1.1.14 | 3ibeA03 | Type II diabetes mellitus, phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153], Aldosterone-regulated sodium reabsorption, Neurotrophin signaling pathway, Melanoma, Leukocyte transendothelial migration, G-protein coupled receptor protein signaling pathway, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Pancreatic cancer, Chemokine signaling pathway, Homo sapiens, T cell receptor signaling pathway, Glioma, Pathways in cancer, Regulation of actin cytoskeleton, ErbB signaling pathway, protein binding, Acute myeloid leukemia, Inositol phosphate metabolism, Small cell lung cancer, Phosphatidylinositol-4,5-bisphosphate 3-kinase., Prostate cancer, Insulin signaling pathway, mTOR signaling pathway, 1-phosphatidylinositol-3-kinase activity, Renal cell carcinoma, Fc gamma R-mediated phagocytosis, Endometrial cancer, VEGF signaling pathway, Toll-like receptor signaling pathway, Apoptosis, Non-small cell lung cancer, Phosphatidylinositol signaling system, Colorectal cancer, Chronic myeloid leukemia, Jak-STAT signaling pathway, Progesterone-mediated oocyte maturation, Natural killer cell mediated cytotoxicity, Fc epsilon RI signaling pathway, B cell receptor signaling pathway, Focal adhesion, Chagas disease | |
|
1.25.40.70.1.1.1.1.15 | 3l13A03 | Homo sapiens, Pancreatic cancer, Chemokine signaling pathway, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, T cell receptor signaling pathway, Leukocyte transendothelial migration, Neurotrophin signaling pathway, Melanoma, phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153], Aldosterone-regulated sodium reabsorption, Type II diabetes mellitus, G-protein coupled receptor protein signaling pathway, Prostate cancer, Phosphatidylinositol-4,5-bisphosphate 3-kinase., Small cell lung cancer, 1-phosphatidylinositol-3-kinase activity, mTOR signaling pathway, Insulin signaling pathway, protein binding, ErbB signaling pathway, Regulation of actin cytoskeleton, Glioma, Pathways in cancer, Inositol phosphate metabolism, Acute myeloid leukemia, Endometrial cancer, Toll-like receptor signaling pathway, Apoptosis, VEGF signaling pathway, Fc gamma R-mediated phagocytosis, Renal cell carcinoma, Fc epsilon RI signaling pathway, B cell receptor signaling pathway, Focal adhesion, Chagas disease, Chronic myeloid leukemia, Colorectal cancer, Phosphatidylinositol signaling system, Non-small cell lung cancer, Natural killer cell mediated cytotoxicity, Progesterone-mediated oocyte maturation, Jak-STAT signaling pathway | |
|
1.25.40.70.1.1.1.1.16 | 3l17A03 | Progesterone-mediated oocyte maturation, Jak-STAT signaling pathway, Natural killer cell mediated cytotoxicity, Non-small cell lung cancer, Phosphatidylinositol signaling system, Colorectal cancer, Chronic myeloid leukemia, Focal adhesion, B cell receptor signaling pathway, Chagas disease, Fc epsilon RI signaling pathway, Renal cell carcinoma, Fc gamma R-mediated phagocytosis, VEGF signaling pathway, Apoptosis, Toll-like receptor signaling pathway, Endometrial cancer, Acute myeloid leukemia, Inositol phosphate metabolism, Pathways in cancer, Glioma, ErbB signaling pathway, Regulation of actin cytoskeleton, protein binding, Insulin signaling pathway, mTOR signaling pathway, 1-phosphatidylinositol-3-kinase activity, Small cell lung cancer, Phosphatidylinositol-4,5-bisphosphate 3-kinase., Prostate cancer, G-protein coupled receptor protein signaling pathway, Type II diabetes mellitus, phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153], Aldosterone-regulated sodium reabsorption, Neurotrophin signaling pathway, Melanoma, Leukocyte transendothelial migration, T cell receptor signaling pathway, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, Chemokine signaling pathway, Pancreatic cancer, Homo sapiens | |
|
1.25.40.70.1.1.1.1.17 | 3cstA03 | Endometrial cancer, Apoptosis, Toll-like receptor signaling pathway, VEGF signaling pathway, Fc gamma R-mediated phagocytosis, Renal cell carcinoma, Fc epsilon RI signaling pathway, Chagas disease, B cell receptor signaling pathway, Focal adhesion, Chronic myeloid leukemia, Colorectal cancer, Phosphatidylinositol signaling system, Non-small cell lung cancer, Natural killer cell mediated cytotoxicity, Progesterone-mediated oocyte maturation, Jak-STAT signaling pathway, Homo sapiens, Pancreatic cancer, Chemokine signaling pathway, Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit gamma isoform, T cell receptor signaling pathway, Melanoma, Neurotrophin signaling pathway, Leukocyte transendothelial migration, phosphatidylinositol-4,5-bisphosphate 3-kinase [EC:2.7.1.153], Aldosterone-regulated sodium reabsorption, Type II diabetes mellitus, G-protein coupled receptor protein signaling pathway, Prostate cancer, Phosphatidylinositol-4,5-bisphosphate 3-kinase., Small cell lung cancer, 1-phosphatidylinositol-3-kinase activity, mTOR signaling pathway, Insulin signaling pathway, protein binding, Regulation of actin cytoskeleton, ErbB signaling pathway, Glioma, Pathways in cancer, Inositol phosphate metabolism, Acute myeloid leukemia |
The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
- Multiple alignments for each functional family
- Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
- Detailed functional information on diversity and conservation within Functional families
- Multi-domain architectures