S100 Family: 1.25.40.20.15.1.1.1
Representative domain: 1iknD00
Classification Lineage (1.25.40.20.15.1.1.1)
Summary of Non-Redundant Representatives
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|---|---|---|---|---|---|---|---|---|
| - | - | - | - | - | - | - | - | 3 |
S100 Count Entries in S100 Family 1.25.40.20.15.1.1.1 (3)
| CATH Level | CATH code | Domain ID | Keywords | Thumbnail |
|---|---|---|---|---|
|
1.25.40.20.15.1.1.1.1 | 1iknD00 | RIG-I-like receptor signaling pathway, identical protein binding, negative regulation of NF-kappaB transcription factor activity, Apoptosis, Toll-like receptor signaling pathway, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha, ubiquitin protein ligase binding, Adipocytokine signaling pathway, positive regulation of cholesterol efflux, negative regulation of lipid storage, Chagas disease, B cell receptor signaling pathway, cytoplasmic sequestering of NF-kappaB, Leishmaniasis, Chronic myeloid leukemia, NOD-like receptor signaling pathway, NF-kappa-B inhibitor alpha, negative regulation of macrophage derived foam cell differentiation, positive regulation of cellular protein metabolic process, nucleus, Homo sapiens, Chemokine signaling pathway, Cytosolic DNA-sensing pathway, T cell receptor signaling pathway, Neurotrophin signaling pathway, NF-kappaB binding, Prostate cancer, Small cell lung cancer, I-kappaB/NF-kappaB complex, nuclear localization sequence binding, Epithelial cell signaling in Helicobacter pylori infection, positive regulation of gene-specific transcription from RNA polymerase II promoter, Pathways in cancer, apoptosis | |
|
1.25.40.20.15.1.1.1.2 | 1nfiE00 | positive regulation of cholesterol efflux, negative regulation of lipid storage, B cell receptor signaling pathway, Chagas disease, cytoplasmic sequestering of NF-kappaB, Chronic myeloid leukemia, Leishmaniasis, NOD-like receptor signaling pathway, NF-kappa-B inhibitor alpha, positive regulation of cellular protein metabolic process, negative regulation of macrophage derived foam cell differentiation, nucleus, RIG-I-like receptor signaling pathway, identical protein binding, negative regulation of NF-kappaB transcription factor activity, Toll-like receptor signaling pathway, Apoptosis, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha, ubiquitin protein ligase binding, Adipocytokine signaling pathway, Prostate cancer, Small cell lung cancer, I-kappaB/NF-kappaB complex, nuclear localization sequence binding, Epithelial cell signaling in Helicobacter pylori infection, positive regulation of gene-specific transcription from RNA polymerase II promoter, Pathways in cancer, apoptosis, Homo sapiens, Chemokine signaling pathway, Cytosolic DNA-sensing pathway, T cell receptor signaling pathway, Neurotrophin signaling pathway, NF-kappaB binding | |
|
1.25.40.20.15.1.1.1.3 | 1nfiF00 | negative regulation of lipid storage, positive regulation of cholesterol efflux, Chagas disease, B cell receptor signaling pathway, cytoplasmic sequestering of NF-kappaB, NOD-like receptor signaling pathway, Chronic myeloid leukemia, Leishmaniasis, nucleus, NF-kappa-B inhibitor alpha, negative regulation of macrophage derived foam cell differentiation, positive regulation of cellular protein metabolic process, negative regulation of NF-kappaB transcription factor activity, RIG-I-like receptor signaling pathway, identical protein binding, Toll-like receptor signaling pathway, Apoptosis, nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha, ubiquitin protein ligase binding, Adipocytokine signaling pathway, Small cell lung cancer, I-kappaB/NF-kappaB complex, Prostate cancer, nuclear localization sequence binding, Epithelial cell signaling in Helicobacter pylori infection, positive regulation of gene-specific transcription from RNA polymerase II promoter, Pathways in cancer, apoptosis, Homo sapiens, Chemokine signaling pathway, T cell receptor signaling pathway, Cytosolic DNA-sensing pathway, Neurotrophin signaling pathway, NF-kappaB binding |
The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
- Multiple alignments for each functional family
- Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
- Detailed functional information on diversity and conservation within Functional families
- Multi-domain architectures