S100 Family: 1.25.40.20.10.1.1.1

Molscript image for 1ympA00
Representative domain: 1ympA00
PDB coordinates for domain 1ympA00

Classification Lineage (1.25.40.20.10.1.1.1)

CATH CodeLevel DescriptionLinks
1 Mainly Alpha
1.25 Alpha Horseshoe
1.25.40 Serine Threonine Protein Phosphatase 5, Tetratricopeptide repeat
1.25.40.20 Gene3D
1.25.40.20.10
1.25.40.20.10.1
1.25.40.20.10.1.1
1.25.40.20.10.1.1.1

Summary of Non-Redundant Representatives

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S100 Count Entries in S100 Family 1.25.40.20.10.1.1.1 (2)

CATH Level CATH code Domain ID Keywords Thumbnail
1.25.40.20.10.1.1.1.1 1ympA00 nucleus, regulation of somitogenesis, somatic stem cell division, compartment pattern formation, lung development, chromatin DNA binding, positive regulation of apoptosis, regulation of epithelial cell proliferation involved in prostate gland development, endocardium morphogenesis, in utero embryonic development, axonogenesis, embryonic hindlimb morphogenesis, prostate gland epithelium morphogenesis, negative regulation of BMP signaling pathway, cell fate specification, liver development, determination of left/right symmetry, negative regulation of osteoblast differentiation, negative regulation of apoptosis, anagen, protein binding, sequence-specific DNA binding, negative regulation of photoreceptor cell differentiation, keratinocyte differentiation, secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development, foregut morphogenesis, Neurogenic locus notch homolog protein 1, neuron fate commitment, sprouting angiogenesis, epithelial to mesenchymal transition, positive regulation of keratinocyte differentiation, Mus musculus, negative regulation of gene-specific transcription, forebrain development, positive regulation of cell proliferation, hair follicle morphogenesis, endoderm development, neural tube development, branching morphogenesis of a tube Molscript image for 1ympA00
1.25.40.20.10.1.1.1.2 1ympB00 negative regulation of BMP signaling pathway, cell fate specification, determination of left/right symmetry, liver development, regulation of epithelial cell proliferation involved in prostate gland development, endocardium morphogenesis, in utero embryonic development, embryonic hindlimb morphogenesis, axonogenesis, prostate gland epithelium morphogenesis, regulation of somitogenesis, somatic stem cell division, compartment pattern formation, positive regulation of apoptosis, lung development, chromatin DNA binding, nucleus, positive regulation of cell proliferation, hair follicle morphogenesis, neural tube development, endoderm development, branching morphogenesis of a tube, sprouting angiogenesis, neuron fate commitment, epithelial to mesenchymal transition, positive regulation of keratinocyte differentiation, forebrain development, Mus musculus, negative regulation of gene-specific transcription, negative regulation of photoreceptor cell differentiation, keratinocyte differentiation, secretory columnal luminar epithelial cell differentiation involved in prostate glandular acinus development, foregut morphogenesis, Neurogenic locus notch homolog protein 1, anagen, negative regulation of apoptosis, negative regulation of osteoblast differentiation, protein binding, sequence-specific DNA binding Molscript image for 1ympB00

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
  • Multiple alignments for each functional family
  • Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
  • Detailed functional information on diversity and conservation within Functional families
  • Multi-domain architectures
In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages: