S100 Family: 1.20.910.10.4.1.1.1

Molscript image for 1n45A00
Representative domain: 1n45A00
PDB coordinates for domain 1n45A00

Classification Lineage (1.20.910.10.4.1.1.1)

CATH CodeLevel DescriptionLinks
1 Mainly Alpha
1.20 Up-down Bundle
1.20.910 Heme Oxygenase; Chain A
1.20.910.10 Heme Oxygenase; Chain A Gene3D
1.20.910.10.4
1.20.910.10.4.1
1.20.910.10.4.1.1
1.20.910.10.4.1.1.1

Summary of Non-Redundant Representatives
- - - - - - - - 32

S100 Count Entries in S100 Family 1.20.910.10.4.1.1.1 (32)

CATH Level CATH code Domain ID Keywords Thumbnail
1.20.910.10.4.1.1.1.1 1n45A00 Homo sapiens, Heme oxygenase., smooth muscle hyperplasia, positive regulation of smooth muscle cell proliferation, low-density lipoprotein particle clearance, Heme oxygenase 1, heme catabolic process, endoplasmic reticulum, extracellular space, wound healing involved in inflammatory response, protein homooligomerization, endothelial cell proliferation, protein homodimerization activity, heme oxygenase (decyclizing) activity, anti-apoptosis, regulation of angiogenesis, positive regulation of I-kappaB kinase/NF-kappaB cascade, iron ion homeostasis, erythrocyte homeostasis, heme oxidation, heme oxygenase [EC:1.14.99.3], signal transducer activity, intracellular protein kinase cascade, positive regulation of chemokine biosynthetic process, angiogenesis, response to nicotine, Porphyrin and chlorophyll metabolism, negative regulation of leukocyte migration, heme binding, negative regulation of smooth muscle cell proliferation Molscript image for 1n45A00
1.20.910.10.4.1.1.1.2 1n45B00 negative regulation of leukocyte migration, Porphyrin and chlorophyll metabolism, response to nicotine, negative regulation of smooth muscle cell proliferation, heme binding, intracellular protein kinase cascade, positive regulation of chemokine biosynthetic process, heme oxygenase [EC:1.14.99.3], signal transducer activity, angiogenesis, erythrocyte homeostasis, heme oxidation, regulation of angiogenesis, iron ion homeostasis, positive regulation of I-kappaB kinase/NF-kappaB cascade, anti-apoptosis, heme oxygenase (decyclizing) activity, protein homodimerization activity, endothelial cell proliferation, wound healing involved in inflammatory response, protein homooligomerization, Heme oxygenase 1, low-density lipoprotein particle clearance, endoplasmic reticulum, extracellular space, heme catabolic process, Heme oxygenase., smooth muscle hyperplasia, Homo sapiens, positive regulation of smooth muscle cell proliferation Molscript image for 1n45B00
1.20.910.10.4.1.1.1.3 3czyA00 Molscript image for 3czyA00
1.20.910.10.4.1.1.1.4 3czyB00 Molscript image for 3czyB00
1.20.910.10.4.1.1.1.5 1ozwA00 positive regulation of smooth muscle cell proliferation, Heme oxygenase., smooth muscle hyperplasia, Homo sapiens, endoplasmic reticulum, extracellular space, heme catabolic process, Heme oxygenase 1, low-density lipoprotein particle clearance, heme oxygenase (decyclizing) activity, protein homodimerization activity, endothelial cell proliferation, protein homooligomerization, wound healing involved in inflammatory response, anti-apoptosis, iron ion homeostasis, positive regulation of I-kappaB kinase/NF-kappaB cascade, regulation of angiogenesis, heme oxidation, erythrocyte homeostasis, angiogenesis, positive regulation of chemokine biosynthetic process, intracellular protein kinase cascade, heme oxygenase [EC:1.14.99.3], signal transducer activity, negative regulation of smooth muscle cell proliferation, heme binding, negative regulation of leukocyte migration, Porphyrin and chlorophyll metabolism, response to nicotine Molscript image for 1ozwA00
1.20.910.10.4.1.1.1.6 1ozwB00 anti-apoptosis, heme oxygenase (decyclizing) activity, protein homodimerization activity, endothelial cell proliferation, protein homooligomerization, wound healing involved in inflammatory response, Heme oxygenase 1, low-density lipoprotein particle clearance, endoplasmic reticulum, extracellular space, heme catabolic process, Heme oxygenase., smooth muscle hyperplasia, Homo sapiens, positive regulation of smooth muscle cell proliferation, negative regulation of leukocyte migration, Porphyrin and chlorophyll metabolism, response to nicotine, negative regulation of smooth muscle cell proliferation, heme binding, positive regulation of chemokine biosynthetic process, intracellular protein kinase cascade, heme oxygenase [EC:1.14.99.3], signal transducer activity, angiogenesis, erythrocyte homeostasis, heme oxidation, regulation of angiogenesis, iron ion homeostasis, positive regulation of I-kappaB kinase/NF-kappaB cascade Molscript image for 1ozwB00
1.20.910.10.4.1.1.1.7 1ozrA00 low-density lipoprotein particle clearance, Heme oxygenase 1, heme catabolic process, endoplasmic reticulum, extracellular space, Homo sapiens, Heme oxygenase., smooth muscle hyperplasia, positive regulation of smooth muscle cell proliferation, anti-apoptosis, wound healing involved in inflammatory response, protein homooligomerization, heme oxygenase (decyclizing) activity, endothelial cell proliferation, protein homodimerization activity, erythrocyte homeostasis, heme oxidation, regulation of angiogenesis, positive regulation of I-kappaB kinase/NF-kappaB cascade, iron ion homeostasis, Porphyrin and chlorophyll metabolism, response to nicotine, negative regulation of leukocyte migration, negative regulation of smooth muscle cell proliferation, heme binding, intracellular protein kinase cascade, positive regulation of chemokine biosynthetic process, heme oxygenase [EC:1.14.99.3], signal transducer activity, angiogenesis Molscript image for 1ozrA00
1.20.910.10.4.1.1.1.8 1ozrB00 erythrocyte homeostasis, heme oxidation, regulation of angiogenesis, positive regulation of I-kappaB kinase/NF-kappaB cascade, iron ion homeostasis, Porphyrin and chlorophyll metabolism, response to nicotine, negative regulation of leukocyte migration, negative regulation of smooth muscle cell proliferation, heme binding, intracellular protein kinase cascade, positive regulation of chemokine biosynthetic process, heme oxygenase [EC:1.14.99.3], signal transducer activity, angiogenesis, low-density lipoprotein particle clearance, Heme oxygenase 1, heme catabolic process, extracellular space, endoplasmic reticulum, Homo sapiens, Heme oxygenase., smooth muscle hyperplasia, positive regulation of smooth muscle cell proliferation, anti-apoptosis, wound healing involved in inflammatory response, protein homooligomerization, heme oxygenase (decyclizing) activity, endothelial cell proliferation, protein homodimerization activity Molscript image for 1ozrB00
1.20.910.10.4.1.1.1.9 1ni6B00 erythrocyte homeostasis, heme oxidation, regulation of angiogenesis, iron ion homeostasis, positive regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of leukocyte migration, response to nicotine, Porphyrin and chlorophyll metabolism, heme binding, negative regulation of smooth muscle cell proliferation, heme oxygenase [EC:1.14.99.3], signal transducer activity, intracellular protein kinase cascade, positive regulation of chemokine biosynthetic process, angiogenesis, Heme oxygenase 1, low-density lipoprotein particle clearance, extracellular space, endoplasmic reticulum, heme catabolic process, Heme oxygenase., smooth muscle hyperplasia, Homo sapiens, positive regulation of smooth muscle cell proliferation, anti-apoptosis, protein homodimerization activity, endothelial cell proliferation, heme oxygenase (decyclizing) activity, protein homooligomerization, wound healing involved in inflammatory response Molscript image for 1ni6B00
1.20.910.10.4.1.1.1.10 1twrA00 positive regulation of smooth muscle cell proliferation, Homo sapiens, Heme oxygenase., smooth muscle hyperplasia, heme catabolic process, endoplasmic reticulum, extracellular space, low-density lipoprotein particle clearance, Heme oxygenase 1, wound healing involved in inflammatory response, protein homooligomerization, protein homodimerization activity, endothelial cell proliferation, heme oxygenase (decyclizing) activity, anti-apoptosis, positive regulation of I-kappaB kinase/NF-kappaB cascade, iron ion homeostasis, regulation of angiogenesis, heme oxidation, erythrocyte homeostasis, angiogenesis, heme oxygenase [EC:1.14.99.3], signal transducer activity, intracellular protein kinase cascade, positive regulation of chemokine biosynthetic process, heme binding, negative regulation of smooth muscle cell proliferation, response to nicotine, Porphyrin and chlorophyll metabolism, negative regulation of leukocyte migration Molscript image for 1twrA00
1.20.910.10.4.1.1.1.11 1twrB00 response to nicotine, Porphyrin and chlorophyll metabolism, negative regulation of leukocyte migration, heme binding, negative regulation of smooth muscle cell proliferation, heme oxygenase [EC:1.14.99.3], signal transducer activity, positive regulation of chemokine biosynthetic process, intracellular protein kinase cascade, angiogenesis, erythrocyte homeostasis, heme oxidation, regulation of angiogenesis, positive regulation of I-kappaB kinase/NF-kappaB cascade, iron ion homeostasis, anti-apoptosis, protein homooligomerization, wound healing involved in inflammatory response, endothelial cell proliferation, protein homodimerization activity, heme oxygenase (decyclizing) activity, low-density lipoprotein particle clearance, Heme oxygenase 1, heme catabolic process, extracellular space, endoplasmic reticulum, Homo sapiens, Heme oxygenase., smooth muscle hyperplasia, positive regulation of smooth muscle cell proliferation Molscript image for 1twrB00
1.20.910.10.4.1.1.1.12 1ni6A00 Heme oxygenase 1, low-density lipoprotein particle clearance, extracellular space, endoplasmic reticulum, heme catabolic process, Heme oxygenase., smooth muscle hyperplasia, Homo sapiens, positive regulation of smooth muscle cell proliferation, anti-apoptosis, heme oxygenase (decyclizing) activity, endothelial cell proliferation, protein homodimerization activity, wound healing involved in inflammatory response, protein homooligomerization, erythrocyte homeostasis, heme oxidation, regulation of angiogenesis, iron ion homeostasis, positive regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of leukocyte migration, Porphyrin and chlorophyll metabolism, response to nicotine, negative regulation of smooth muscle cell proliferation, heme binding, intracellular protein kinase cascade, positive regulation of chemokine biosynthetic process, heme oxygenase [EC:1.14.99.3], signal transducer activity, angiogenesis Molscript image for 1ni6A00
1.20.910.10.4.1.1.1.13 1ni6D00 erythrocyte homeostasis, heme oxidation, regulation of angiogenesis, iron ion homeostasis, positive regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of leukocyte migration, response to nicotine, Porphyrin and chlorophyll metabolism, heme binding, negative regulation of smooth muscle cell proliferation, heme oxygenase [EC:1.14.99.3], signal transducer activity, positive regulation of chemokine biosynthetic process, intracellular protein kinase cascade, angiogenesis, Heme oxygenase 1, low-density lipoprotein particle clearance, extracellular space, endoplasmic reticulum, heme catabolic process, Heme oxygenase., smooth muscle hyperplasia, Homo sapiens, positive regulation of smooth muscle cell proliferation, anti-apoptosis, protein homodimerization activity, endothelial cell proliferation, heme oxygenase (decyclizing) activity, wound healing involved in inflammatory response, protein homooligomerization Molscript image for 1ni6D00
1.20.910.10.4.1.1.1.14 3k4fA00 negative regulation of smooth muscle cell proliferation, heme binding, Porphyrin and chlorophyll metabolism, response to nicotine, negative regulation of leukocyte migration, angiogenesis, positive regulation of chemokine biosynthetic process, intracellular protein kinase cascade, heme oxygenase [EC:1.14.99.3], signal transducer activity, heme oxidation, erythrocyte homeostasis, positive regulation of I-kappaB kinase/NF-kappaB cascade, iron ion homeostasis, regulation of angiogenesis, anti-apoptosis, protein homooligomerization, wound healing involved in inflammatory response, heme oxygenase (decyclizing) activity, endothelial cell proliferation, protein homodimerization activity, heme catabolic process, endoplasmic reticulum, extracellular space, low-density lipoprotein particle clearance, Heme oxygenase 1, positive regulation of smooth muscle cell proliferation, Homo sapiens, Heme oxygenase., smooth muscle hyperplasia Molscript image for 3k4fA00
1.20.910.10.4.1.1.1.15 3k4fB00 anti-apoptosis, heme oxygenase (decyclizing) activity, protein homodimerization activity, endothelial cell proliferation, protein homooligomerization, wound healing involved in inflammatory response, Heme oxygenase 1, low-density lipoprotein particle clearance, extracellular space, endoplasmic reticulum, heme catabolic process, Heme oxygenase., smooth muscle hyperplasia, Homo sapiens, positive regulation of smooth muscle cell proliferation, negative regulation of leukocyte migration, Porphyrin and chlorophyll metabolism, response to nicotine, negative regulation of smooth muscle cell proliferation, heme binding, positive regulation of chemokine biosynthetic process, intracellular protein kinase cascade, heme oxygenase [EC:1.14.99.3], signal transducer activity, angiogenesis, erythrocyte homeostasis, heme oxidation, regulation of angiogenesis, iron ion homeostasis, positive regulation of I-kappaB kinase/NF-kappaB cascade Molscript image for 3k4fB00
1.20.910.10.4.1.1.1.16 1s8cA00 heme oxidation, erythrocyte homeostasis, iron ion homeostasis, positive regulation of I-kappaB kinase/NF-kappaB cascade, regulation of angiogenesis, negative regulation of smooth muscle cell proliferation, heme binding, negative regulation of leukocyte migration, Porphyrin and chlorophyll metabolism, response to nicotine, angiogenesis, positive regulation of chemokine biosynthetic process, intracellular protein kinase cascade, heme oxygenase [EC:1.14.99.3], signal transducer activity, endoplasmic reticulum, extracellular space, heme catabolic process, Heme oxygenase 1, low-density lipoprotein particle clearance, positive regulation of smooth muscle cell proliferation, Heme oxygenase., smooth muscle hyperplasia, Homo sapiens, anti-apoptosis, heme oxygenase (decyclizing) activity, protein homodimerization activity, endothelial cell proliferation, wound healing involved in inflammatory response, protein homooligomerization Molscript image for 1s8cA00
1.20.910.10.4.1.1.1.17 1s8cB00 heme catabolic process, extracellular space, endoplasmic reticulum, low-density lipoprotein particle clearance, Heme oxygenase 1, positive regulation of smooth muscle cell proliferation, Homo sapiens, Heme oxygenase., smooth muscle hyperplasia, anti-apoptosis, wound healing involved in inflammatory response, protein homooligomerization, heme oxygenase (decyclizing) activity, endothelial cell proliferation, protein homodimerization activity, heme oxidation, erythrocyte homeostasis, positive regulation of I-kappaB kinase/NF-kappaB cascade, iron ion homeostasis, regulation of angiogenesis, negative regulation of smooth muscle cell proliferation, heme binding, Porphyrin and chlorophyll metabolism, response to nicotine, negative regulation of leukocyte migration, angiogenesis, positive regulation of chemokine biosynthetic process, intracellular protein kinase cascade, heme oxygenase [EC:1.14.99.3], signal transducer activity Molscript image for 1s8cB00
1.20.910.10.4.1.1.1.18 1s8cC00 anti-apoptosis, endothelial cell proliferation, protein homodimerization activity, heme oxygenase (decyclizing) activity, protein homooligomerization, wound healing involved in inflammatory response, Heme oxygenase 1, low-density lipoprotein particle clearance, extracellular space, endoplasmic reticulum, heme catabolic process, Heme oxygenase., smooth muscle hyperplasia, Homo sapiens, positive regulation of smooth muscle cell proliferation, negative regulation of leukocyte migration, response to nicotine, Porphyrin and chlorophyll metabolism, heme binding, negative regulation of smooth muscle cell proliferation, heme oxygenase [EC:1.14.99.3], signal transducer activity, positive regulation of chemokine biosynthetic process, intracellular protein kinase cascade, angiogenesis, erythrocyte homeostasis, heme oxidation, regulation of angiogenesis, iron ion homeostasis, positive regulation of I-kappaB kinase/NF-kappaB cascade Molscript image for 1s8cC00
1.20.910.10.4.1.1.1.19 3hokA00 angiogenesis, heme oxygenase [EC:1.14.99.3], signal transducer activity, positive regulation of chemokine biosynthetic process, intracellular protein kinase cascade, heme binding, negative regulation of smooth muscle cell proliferation, response to nicotine, Porphyrin and chlorophyll metabolism, negative regulation of leukocyte migration, positive regulation of I-kappaB kinase/NF-kappaB cascade, iron ion homeostasis, regulation of angiogenesis, heme oxidation, erythrocyte homeostasis, protein homooligomerization, wound healing involved in inflammatory response, protein homodimerization activity, endothelial cell proliferation, heme oxygenase (decyclizing) activity, anti-apoptosis, positive regulation of smooth muscle cell proliferation, Homo sapiens, Heme oxygenase., smooth muscle hyperplasia, heme catabolic process, endoplasmic reticulum, extracellular space, low-density lipoprotein particle clearance, Heme oxygenase 1 Molscript image for 3hokA00
1.20.910.10.4.1.1.1.20 3hokB00 heme oxygenase (decyclizing) activity, protein homodimerization activity, endothelial cell proliferation, wound healing involved in inflammatory response, protein homooligomerization, anti-apoptosis, positive regulation of smooth muscle cell proliferation, Heme oxygenase., smooth muscle hyperplasia, Homo sapiens, extracellular space, endoplasmic reticulum, heme catabolic process, Heme oxygenase 1, low-density lipoprotein particle clearance, angiogenesis, intracellular protein kinase cascade, positive regulation of chemokine biosynthetic process, heme oxygenase [EC:1.14.99.3], signal transducer activity, negative regulation of smooth muscle cell proliferation, heme binding, negative regulation of leukocyte migration, Porphyrin and chlorophyll metabolism, response to nicotine, iron ion homeostasis, positive regulation of I-kappaB kinase/NF-kappaB cascade, regulation of angiogenesis, heme oxidation, erythrocyte homeostasis Molscript image for 3hokB00
1.20.910.10.4.1.1.1.21 1twnA00 regulation of angiogenesis, positive regulation of I-kappaB kinase/NF-kappaB cascade, iron ion homeostasis, erythrocyte homeostasis, heme oxidation, heme oxygenase [EC:1.14.99.3], signal transducer activity, intracellular protein kinase cascade, positive regulation of chemokine biosynthetic process, angiogenesis, response to nicotine, Porphyrin and chlorophyll metabolism, negative regulation of leukocyte migration, heme binding, negative regulation of smooth muscle cell proliferation, Homo sapiens, Heme oxygenase., smooth muscle hyperplasia, positive regulation of smooth muscle cell proliferation, low-density lipoprotein particle clearance, Heme oxygenase 1, heme catabolic process, extracellular space, endoplasmic reticulum, protein homooligomerization, wound healing involved in inflammatory response, protein homodimerization activity, endothelial cell proliferation, heme oxygenase (decyclizing) activity, anti-apoptosis Molscript image for 1twnA00
1.20.910.10.4.1.1.1.22 1twnB00 heme oxygenase [EC:1.14.99.3], signal transducer activity, intracellular protein kinase cascade, positive regulation of chemokine biosynthetic process, angiogenesis, negative regulation of leukocyte migration, response to nicotine, Porphyrin and chlorophyll metabolism, heme binding, negative regulation of smooth muscle cell proliferation, regulation of angiogenesis, iron ion homeostasis, positive regulation of I-kappaB kinase/NF-kappaB cascade, erythrocyte homeostasis, heme oxidation, protein homodimerization activity, endothelial cell proliferation, heme oxygenase (decyclizing) activity, protein homooligomerization, wound healing involved in inflammatory response, anti-apoptosis, Heme oxygenase., smooth muscle hyperplasia, Homo sapiens, positive regulation of smooth muscle cell proliferation, Heme oxygenase 1, low-density lipoprotein particle clearance, endoplasmic reticulum, extracellular space, heme catabolic process Molscript image for 1twnB00
1.20.910.10.4.1.1.1.23 1s8cD00 Heme oxygenase., smooth muscle hyperplasia, Homo sapiens, positive regulation of smooth muscle cell proliferation, Heme oxygenase 1, low-density lipoprotein particle clearance, extracellular space, endoplasmic reticulum, heme catabolic process, heme oxygenase (decyclizing) activity, endothelial cell proliferation, protein homodimerization activity, protein homooligomerization, wound healing involved in inflammatory response, anti-apoptosis, regulation of angiogenesis, iron ion homeostasis, positive regulation of I-kappaB kinase/NF-kappaB cascade, erythrocyte homeostasis, heme oxidation, positive regulation of chemokine biosynthetic process, intracellular protein kinase cascade, heme oxygenase [EC:1.14.99.3], signal transducer activity, angiogenesis, negative regulation of leukocyte migration, Porphyrin and chlorophyll metabolism, response to nicotine, negative regulation of smooth muscle cell proliferation, heme binding Molscript image for 1s8cD00
1.20.910.10.4.1.1.1.24 1ni6C00 erythrocyte homeostasis, heme oxidation, regulation of angiogenesis, positive regulation of I-kappaB kinase/NF-kappaB cascade, iron ion homeostasis, Porphyrin and chlorophyll metabolism, response to nicotine, negative regulation of leukocyte migration, negative regulation of smooth muscle cell proliferation, heme binding, intracellular protein kinase cascade, positive regulation of chemokine biosynthetic process, heme oxygenase [EC:1.14.99.3], signal transducer activity, angiogenesis, low-density lipoprotein particle clearance, Heme oxygenase 1, heme catabolic process, extracellular space, endoplasmic reticulum, Homo sapiens, Heme oxygenase., smooth muscle hyperplasia, positive regulation of smooth muscle cell proliferation, anti-apoptosis, protein homooligomerization, wound healing involved in inflammatory response, heme oxygenase (decyclizing) activity, protein homodimerization activity, endothelial cell proliferation Molscript image for 1ni6C00
1.20.910.10.4.1.1.1.25 1t5pA00 erythrocyte homeostasis, heme oxidation, regulation of angiogenesis, iron ion homeostasis, positive regulation of I-kappaB kinase/NF-kappaB cascade, negative regulation of leukocyte migration, response to nicotine, Porphyrin and chlorophyll metabolism, heme binding, negative regulation of smooth muscle cell proliferation, heme oxygenase [EC:1.14.99.3], signal transducer activity, intracellular protein kinase cascade, positive regulation of chemokine biosynthetic process, angiogenesis, Heme oxygenase 1, low-density lipoprotein particle clearance, endoplasmic reticulum, extracellular space, heme catabolic process, Heme oxygenase., smooth muscle hyperplasia, Homo sapiens, positive regulation of smooth muscle cell proliferation, anti-apoptosis, protein homodimerization activity, endothelial cell proliferation, heme oxygenase (decyclizing) activity, wound healing involved in inflammatory response, protein homooligomerization Molscript image for 1t5pA00
1.20.910.10.4.1.1.1.26 1s13A00 iron ion homeostasis, positive regulation of I-kappaB kinase/NF-kappaB cascade, regulation of angiogenesis, heme oxidation, erythrocyte homeostasis, angiogenesis, heme oxygenase [EC:1.14.99.3], signal transducer activity, intracellular protein kinase cascade, positive regulation of chemokine biosynthetic process, heme binding, negative regulation of smooth muscle cell proliferation, negative regulation of leukocyte migration, response to nicotine, Porphyrin and chlorophyll metabolism, positive regulation of smooth muscle cell proliferation, Heme oxygenase., smooth muscle hyperplasia, Homo sapiens, endoplasmic reticulum, extracellular space, heme catabolic process, Heme oxygenase 1, low-density lipoprotein particle clearance, endothelial cell proliferation, protein homodimerization activity, heme oxygenase (decyclizing) activity, wound healing involved in inflammatory response, protein homooligomerization, anti-apoptosis Molscript image for 1s13A00
1.20.910.10.4.1.1.1.27 1s13B00 negative regulation of smooth muscle cell proliferation, heme binding, negative regulation of leukocyte migration, Porphyrin and chlorophyll metabolism, response to nicotine, angiogenesis, positive regulation of chemokine biosynthetic process, intracellular protein kinase cascade, heme oxygenase [EC:1.14.99.3], signal transducer activity, heme oxidation, erythrocyte homeostasis, iron ion homeostasis, positive regulation of I-kappaB kinase/NF-kappaB cascade, regulation of angiogenesis, anti-apoptosis, heme oxygenase (decyclizing) activity, protein homodimerization activity, endothelial cell proliferation, protein homooligomerization, wound healing involved in inflammatory response, endoplasmic reticulum, extracellular space, heme catabolic process, Heme oxygenase 1, low-density lipoprotein particle clearance, positive regulation of smooth muscle cell proliferation, Heme oxygenase., smooth muscle hyperplasia, Homo sapiens Molscript image for 1s13B00
1.20.910.10.4.1.1.1.28 1t5pB00 heme oxidation, erythrocyte homeostasis, iron ion homeostasis, positive regulation of I-kappaB kinase/NF-kappaB cascade, regulation of angiogenesis, negative regulation of smooth muscle cell proliferation, heme binding, negative regulation of leukocyte migration, Porphyrin and chlorophyll metabolism, response to nicotine, angiogenesis, positive regulation of chemokine biosynthetic process, intracellular protein kinase cascade, heme oxygenase [EC:1.14.99.3], signal transducer activity, extracellular space, endoplasmic reticulum, heme catabolic process, Heme oxygenase 1, low-density lipoprotein particle clearance, positive regulation of smooth muscle cell proliferation, Heme oxygenase., smooth muscle hyperplasia, Homo sapiens, anti-apoptosis, heme oxygenase (decyclizing) activity, protein homodimerization activity, endothelial cell proliferation, protein homooligomerization, wound healing involved in inflammatory response Molscript image for 1t5pB00
1.20.910.10.4.1.1.1.29 1n3uA00 positive regulation of I-kappaB kinase/NF-kappaB cascade, iron ion homeostasis, regulation of angiogenesis, heme oxidation, erythrocyte homeostasis, angiogenesis, heme oxygenase [EC:1.14.99.3], signal transducer activity, positive regulation of chemokine biosynthetic process, intracellular protein kinase cascade, heme binding, negative regulation of smooth muscle cell proliferation, response to nicotine, Porphyrin and chlorophyll metabolism, negative regulation of leukocyte migration, positive regulation of smooth muscle cell proliferation, Homo sapiens, Heme oxygenase., smooth muscle hyperplasia, heme catabolic process, extracellular space, endoplasmic reticulum, low-density lipoprotein particle clearance, Heme oxygenase 1, protein homooligomerization, wound healing involved in inflammatory response, protein homodimerization activity, endothelial cell proliferation, heme oxygenase (decyclizing) activity, anti-apoptosis Molscript image for 1n3uA00
1.20.910.10.4.1.1.1.30 1n3uB00 protein homooligomerization, wound healing involved in inflammatory response, endothelial cell proliferation, protein homodimerization activity, heme oxygenase (decyclizing) activity, anti-apoptosis, positive regulation of smooth muscle cell proliferation, Homo sapiens, Heme oxygenase., smooth muscle hyperplasia, heme catabolic process, endoplasmic reticulum, extracellular space, low-density lipoprotein particle clearance, Heme oxygenase 1, angiogenesis, heme oxygenase [EC:1.14.99.3], signal transducer activity, positive regulation of chemokine biosynthetic process, intracellular protein kinase cascade, heme binding, negative regulation of smooth muscle cell proliferation, response to nicotine, Porphyrin and chlorophyll metabolism, negative regulation of leukocyte migration, positive regulation of I-kappaB kinase/NF-kappaB cascade, iron ion homeostasis, regulation of angiogenesis, heme oxidation, erythrocyte homeostasis Molscript image for 1n3uB00
1.20.910.10.4.1.1.1.31 1qq8A00 Molscript image for 1qq8A00
1.20.910.10.4.1.1.1.32 1qq8B00 Molscript image for 1qq8B00

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
  • Multiple alignments for each functional family
  • Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
  • Detailed functional information on diversity and conservation within Functional families
  • Multi-domain architectures
In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages:
http://gene3d.biochem.ucl.ac.uk/superfamily/?accession=1.20.910.10.4.1.1.1