S100 Family: 1.20.5.170.5.1.1.1

Molscript image for 1jnmA00
Representative domain: 1jnmA00
PDB coordinates for domain 1jnmA00

Classification Lineage (1.20.5.170.5.1.1.1)

CATH CodeLevel DescriptionLinks
1 Mainly Alpha
1.20 Up-down Bundle
1.20.5 Single alpha-helices involved in coiled-coils or other helix-helix interfaces
1.20.5.170 Gene3D
1.20.5.170.5
1.20.5.170.5.1
1.20.5.170.5.1.1
1.20.5.170.5.1.1.1

Summary of Non-Redundant Representatives

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S100 Count Entries in S100 Family 1.20.5.170.5.1.1.1 (6)

CATH Level CATH code Domain ID Keywords Thumbnail
1.20.5.170.5.1.1.1.1 1jnmA00 ErbB signaling pathway, Epithelial cell signaling in Helicobacter pylori infection, Pathways in cancer, SMAD protein import into nucleus, transcription coactivator activity, Rho GTPase activator activity, R-SMAD binding, positive regulation of transcription from RNA polymerase II promoter, Transcription factor AP-1, MAPK signaling pathway, Neurotrophin signaling pathway, transcription repressor activity, positive regulation by host of viral transcription, Wnt signaling pathway, Homo sapiens, transcription factor AP-1, T cell receptor signaling pathway, transforming growth factor beta receptor signaling pathway, Leishmaniasis, Colorectal cancer, negative regulation of DNA binding, Chagas disease, B cell receptor signaling pathway, Focal adhesion, Renal cell carcinoma, promoter binding, SMAD protein signal transduction, sequence-specific enhancer binding RNA polymerase II transcription factor activity, GnRH signaling pathway, Toll-like receptor signaling pathway Molscript image for 1jnmA00
1.20.5.170.5.1.1.1.2 1jnmB00 Neurotrophin signaling pathway, transcription repressor activity, positive regulation by host of viral transcription, Wnt signaling pathway, Homo sapiens, transcription factor AP-1, T cell receptor signaling pathway, transforming growth factor beta receptor signaling pathway, ErbB signaling pathway, Epithelial cell signaling in Helicobacter pylori infection, Pathways in cancer, transcription coactivator activity, SMAD protein import into nucleus, R-SMAD binding, Rho GTPase activator activity, positive regulation of transcription from RNA polymerase II promoter, Transcription factor AP-1, MAPK signaling pathway, Renal cell carcinoma, SMAD protein signal transduction, promoter binding, sequence-specific enhancer binding RNA polymerase II transcription factor activity, GnRH signaling pathway, Toll-like receptor signaling pathway, Leishmaniasis, Colorectal cancer, negative regulation of DNA binding, Focal adhesion, B cell receptor signaling pathway, Chagas disease Molscript image for 1jnmB00
1.20.5.170.5.1.1.1.3 2h7hA00 Avian sarcoma virus 17, Viral jun-transforming protein Molscript image for 2h7hA00
1.20.5.170.5.1.1.1.4 2h7hB00 Avian sarcoma virus 17, Viral jun-transforming protein Molscript image for 2h7hB00
1.20.5.170.5.1.1.1.5 1fosF00 Toll-like receptor signaling pathway, GnRH signaling pathway, sequence-specific enhancer binding RNA polymerase II transcription factor activity, promoter binding, SMAD protein signal transduction, Renal cell carcinoma, Focal adhesion, B cell receptor signaling pathway, Chagas disease, negative regulation of DNA binding, Leishmaniasis, Colorectal cancer, transcription factor AP-1, T cell receptor signaling pathway, transforming growth factor beta receptor signaling pathway, Homo sapiens, positive regulation by host of viral transcription, Wnt signaling pathway, transcription repressor activity, Neurotrophin signaling pathway, Transcription factor AP-1, MAPK signaling pathway, positive regulation of transcription from RNA polymerase II promoter, R-SMAD binding, Rho GTPase activator activity, transcription coactivator activity, SMAD protein import into nucleus, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Pathways in cancer Molscript image for 1fosF00
1.20.5.170.5.1.1.1.6 1fosH00 Chagas disease, Focal adhesion, B cell receptor signaling pathway, negative regulation of DNA binding, Leishmaniasis, Colorectal cancer, GnRH signaling pathway, Toll-like receptor signaling pathway, sequence-specific enhancer binding RNA polymerase II transcription factor activity, Renal cell carcinoma, SMAD protein signal transduction, promoter binding, Transcription factor AP-1, MAPK signaling pathway, positive regulation of transcription from RNA polymerase II promoter, Rho GTPase activator activity, R-SMAD binding, Epithelial cell signaling in Helicobacter pylori infection, ErbB signaling pathway, Pathways in cancer, SMAD protein import into nucleus, transcription coactivator activity, transcription factor AP-1, T cell receptor signaling pathway, transforming growth factor beta receptor signaling pathway, Homo sapiens, transcription repressor activity, positive regulation by host of viral transcription, Wnt signaling pathway, Neurotrophin signaling pathway Molscript image for 1fosH00

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
  • Multiple alignments for each functional family
  • Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
  • Detailed functional information on diversity and conservation within Functional families
  • Multi-domain architectures
In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages: