S100 Family: 1.20.1250.10.7.1.1.1

Molscript image for 3besL00
Representative domain: 3besL00
PDB coordinates for domain 3besL00

Classification Lineage (1.20.1250.10.7.1.1.1)

CATH CodeLevel DescriptionLinks
1 Mainly Alpha
1.20 Up-down Bundle
1.20.1250 Growth Hormone; Chain: A;
1.20.1250.10 Gene3D
1.20.1250.10.7
1.20.1250.10.7.1
1.20.1250.10.7.1.1
1.20.1250.10.7.1.1.1

Summary of Non-Redundant Representatives
- - - - - - - - 3

S100 Count Entries in S100 Family 1.20.1250.10.7.1.1.1 (3)

CATH Level CATH code Domain ID Keywords Thumbnail
1.20.1250.10.7.1.1.1.1 3besL00 cell cycle arrest, positive regulation of peptidyl-serine phosphorylation of STAT protein, Homo sapiens, positive regulation of tyrosine phosphorylation of Stat1 protein, regulation of insulin secretion, interferon, gamma, Systemic lupus erythematosus, TGF-beta signaling pathway, T cell receptor signaling pathway, positive regulation of calcidiol 1-monooxygenase activity, cell surface receptor linked signaling pathway, response to virus, Type I diabetes mellitus, positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity, positive regulation of killing of cells of another organism, Proteasome, Interferon gamma, Antigen processing and presentation, interferon-gamma receptor binding, Cytokine-cytokine receptor interaction, Regulation of autophagy, positive regulation of membrane protein ectodomain proteolysis, Leishmaniasis, positive regulation of smooth muscle cell apoptosis, Natural killer cell mediated cytotoxicity, protein import into nucleus, translocation, Jak-STAT signaling pathway, positive regulation of fructose 1,6-bisphosphate metabolic process, negative regulation of smooth muscle cell proliferation, Allograft rejection, positive regulation of vitamin D biosynthetic process, Graft-versus-host disease, tyrosine phosphorylation of Stat1 protein, positive regulation of nitric oxide biosynthetic process, Chagas disease, positive regulation of interleukin-12 production Molscript image for 3besL00
1.20.1250.10.7.1.1.1.2 1fg9A00 Chagas disease, positive regulation of interleukin-12 production, positive regulation of nitric oxide biosynthetic process, Graft-versus-host disease, tyrosine phosphorylation of Stat1 protein, Allograft rejection, positive regulation of vitamin D biosynthetic process, Jak-STAT signaling pathway, negative regulation of smooth muscle cell proliferation, positive regulation of fructose 1,6-bisphosphate metabolic process, protein import into nucleus, translocation, Natural killer cell mediated cytotoxicity, positive regulation of smooth muscle cell apoptosis, Leishmaniasis, positive regulation of membrane protein ectodomain proteolysis, Regulation of autophagy, Cytokine-cytokine receptor interaction, Antigen processing and presentation, interferon-gamma receptor binding, Interferon gamma, Proteasome, positive regulation of killing of cells of another organism, positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity, Type I diabetes mellitus, response to virus, cell surface receptor linked signaling pathway, positive regulation of calcidiol 1-monooxygenase activity, TGF-beta signaling pathway, T cell receptor signaling pathway, Systemic lupus erythematosus, interferon, gamma, regulation of insulin secretion, positive regulation of tyrosine phosphorylation of Stat1 protein, Homo sapiens, positive regulation of peptidyl-serine phosphorylation of STAT protein, cell cycle arrest Molscript image for 1fg9A00
1.20.1250.10.7.1.1.1.3 1fg9B00 Cytokine-cytokine receptor interaction, Antigen processing and presentation, interferon-gamma receptor binding, Interferon gamma, Proteasome, positive regulation of membrane protein ectodomain proteolysis, Regulation of autophagy, protein import into nucleus, translocation, Jak-STAT signaling pathway, positive regulation of fructose 1,6-bisphosphate metabolic process, negative regulation of smooth muscle cell proliferation, positive regulation of smooth muscle cell apoptosis, Natural killer cell mediated cytotoxicity, Leishmaniasis, Chagas disease, positive regulation of interleukin-12 production, positive regulation of nitric oxide biosynthetic process, Graft-versus-host disease, tyrosine phosphorylation of Stat1 protein, Allograft rejection, positive regulation of vitamin D biosynthetic process, positive regulation of peptidyl-serine phosphorylation of STAT protein, cell cycle arrest, Systemic lupus erythematosus, T cell receptor signaling pathway, TGF-beta signaling pathway, interferon, gamma, regulation of insulin secretion, Homo sapiens, positive regulation of tyrosine phosphorylation of Stat1 protein, Type I diabetes mellitus, response to virus, cell surface receptor linked signaling pathway, positive regulation of calcidiol 1-monooxygenase activity, positive regulation of killing of cells of another organism, positive regulation of fructose 1,6-bisphosphate 1-phosphatase activity Molscript image for 1fg9B00

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
  • Multiple alignments for each functional family
  • Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
  • Detailed functional information on diversity and conservation within Functional families
  • Multi-domain architectures
In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages:
http://gene3d.biochem.ucl.ac.uk/superfamily/?accession=1.20.1250.10.7.1.1.1