S100 Family: 1.10.150.20.9.1.1.1

Representative domain: 2fmpA02

Classification Lineage (1.10.150.20.9.1.1.1)

CATH Code	Level Description	Links
1	Mainly Alpha
1.10	Orthogonal Bundle
1.10.150	DNA polymerase; domain 1
1.10.150.20	5' to 3' exonuclease, C-terminal subdomain	Gene3D
1.10.150.20.9
1.10.150.20.9.1
1.10.150.20.9.1.1
1.10.150.20.9.1.1.1

Summary of Non-Redundant Representatives


-	-	-	-	-	-	-	-	118

Non-Redundant Representatives (118)
Functional Families
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What is a Non-Redundant Representative?

CATH is a tree-like organisation of nodes that begins with the class node (i.e. the first branch-point of the tree) and ends with the domain nodes (i.e. the leaves of the tree). Each node below the class have a parent that they belong to, e.g. the parent of the H level (Homologous superfamily) is the T (Topology). Additionally, each node above the domains have child nodes that belong to them, e.g. the child nodes of a given H (Homologous superfamily) level are the S35 families (domains clustered at > 35% sequence identity).

S100 Count Entries in S100 Family 1.10.150.20.9.1.1.1 (118)

CATH code	Domain ID	Keywords
1.10.150.20.9.1.1.1.1	2fmpA02	cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, base-excision repair, Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-]
1.10.150.20.9.1.1.1.2	3jpqA02	enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, base-excision repair
1.10.150.20.9.1.1.1.3	1tv9A02	enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, base-excision repair
1.10.150.20.9.1.1.1.4	2fmsA02	cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., base-excision repair, Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-]
1.10.150.20.9.1.1.1.5	3isbA02	DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, base-excision repair, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens
1.10.150.20.9.1.1.1.6	3iscA02	spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, base-excision repair, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens
1.10.150.20.9.1.1.1.7	3jpoA02	Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, base-excision repair
1.10.150.20.9.1.1.1.8	3jpsA02	spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, base-excision repair, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens
1.10.150.20.9.1.1.1.9	1zjmA02	base-excision repair, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases.
1.10.150.20.9.1.1.1.10	2i9gA02	cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, base-excision repair, Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-]
1.10.150.20.9.1.1.1.11	2isoA02	cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, base-excision repair, Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-]
1.10.150.20.9.1.1.1.12	2pxiA02	enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, base-excision repair
1.10.150.20.9.1.1.1.13	3jppA02	DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, base-excision repair, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens
1.10.150.20.9.1.1.1.14	3jprA02	Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, base-excision repair
1.10.150.20.9.1.1.1.15	3c2mA02	Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, base-excision repair, cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication
1.10.150.20.9.1.1.1.16	3jpnA02	base-excision repair, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases.
1.10.150.20.9.1.1.1.17	3jptA02	lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, base-excision repair, cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair
1.10.150.20.9.1.1.1.18	1bpyA02	DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., base-excision repair, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm
1.10.150.20.9.1.1.1.19	2fmqA02	cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, base-excision repair, enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-]
1.10.150.20.9.1.1.1.20	2ispA02	microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, base-excision repair, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity
1.10.150.20.9.1.1.1.21	3gdxA02	microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, base-excision repair, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity
1.10.150.20.9.1.1.1.22	1bpxA02	DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., base-excision repair, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm
1.10.150.20.9.1.1.1.23	3c2kA02	Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., base-excision repair
1.10.150.20.9.1.1.1.24	2p66A02	Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, base-excision repair, DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase.
1.10.150.20.9.1.1.1.25	1bpzA02	Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, base-excision repair, cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule
1.10.150.20.9.1.1.1.26	1tvaA02	DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, base-excision repair, cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding
1.10.150.20.9.1.1.1.27	3c2lA02	DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., base-excision repair, cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding
1.10.150.20.9.1.1.1.28	3isdA02	base-excision repair, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding
1.10.150.20.9.1.1.1.29	9icwA02	Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, base-excision repair, cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication
1.10.150.20.9.1.1.1.30	9icxA02	DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding, base-excision repair, DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm
1.10.150.20.9.1.1.1.31	1zjnA02	DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, base-excision repair, cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding
1.10.150.20.9.1.1.1.32	1zqiA02	lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, base-excision repair, cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair
1.10.150.20.9.1.1.1.33	8ickA02	DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., base-excision repair, cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding
1.10.150.20.9.1.1.1.34	8icoA02	spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, base-excision repair, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens
1.10.150.20.9.1.1.1.35	9ickA02	DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., base-excision repair, cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding
1.10.150.20.9.1.1.1.36	9icvA02	base-excision repair, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases.
1.10.150.20.9.1.1.1.37	1mq3A02	DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., base-excision repair, cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding
1.10.150.20.9.1.1.1.38	1zqpA02	Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding, DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., base-excision repair, cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication
1.10.150.20.9.1.1.1.39	7iceA02	DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., base-excision repair, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm
1.10.150.20.9.1.1.1.40	7iciA02	Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, base-excision repair, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity
1.10.150.20.9.1.1.1.41	7icnA02	enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, base-excision repair
1.10.150.20.9.1.1.1.42	7icsA02	Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, base-excision repair, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity
1.10.150.20.9.1.1.1.43	7ictA02	lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, base-excision repair, cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair
1.10.150.20.9.1.1.1.44	7icvA02	DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., base-excision repair, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm
1.10.150.20.9.1.1.1.45	8iccA02	DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, base-excision repair, cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair
1.10.150.20.9.1.1.1.46	8iciA02	Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, base-excision repair, DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase.
1.10.150.20.9.1.1.1.47	8icnA02	DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding, base-excision repair, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm
1.10.150.20.9.1.1.1.48	9iclA02	base-excision repair, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases.
1.10.150.20.9.1.1.1.49	1zqfA02	enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, base-excision repair
1.10.150.20.9.1.1.1.50	7ichA02	enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, base-excision repair
1.10.150.20.9.1.1.1.51	7ickA02	microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, base-excision repair, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity
1.10.150.20.9.1.1.1.52	7icqA02	lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, base-excision repair, cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair
1.10.150.20.9.1.1.1.53	8icfA02	Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, base-excision repair, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity
1.10.150.20.9.1.1.1.54	8icmA02	DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, base-excision repair, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens
1.10.150.20.9.1.1.1.55	8icpA02	DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, base-excision repair, DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens
1.10.150.20.9.1.1.1.56	8icrA02	base-excision repair, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases.
1.10.150.20.9.1.1.1.57	8icsA02	enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, base-excision repair
1.10.150.20.9.1.1.1.58	9ichA02	spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, base-excision repair, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens
1.10.150.20.9.1.1.1.59	9icmA02	Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, base-excision repair, DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase.
1.10.150.20.9.1.1.1.60	9icoA02	DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., base-excision repair, cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding
1.10.150.20.9.1.1.1.61	9icqA02	microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, base-excision repair, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity
1.10.150.20.9.1.1.1.62	9icsA02	DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding, base-excision repair, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm
1.10.150.20.9.1.1.1.63	9icuA02	DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, base-excision repair, cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding
1.10.150.20.9.1.1.1.64	1zqnA02	Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., base-excision repair
1.10.150.20.9.1.1.1.65	7icgA02	DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., base-excision repair, cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding
1.10.150.20.9.1.1.1.66	7icmA02	spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, base-excision repair, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens
1.10.150.20.9.1.1.1.67	7icpA02	Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., base-excision repair
1.10.150.20.9.1.1.1.68	7icrA02	cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, base-excision repair, enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-]
1.10.150.20.9.1.1.1.69	8icaA02	DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., base-excision repair, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm
1.10.150.20.9.1.1.1.70	8icqA02	Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, base-excision repair, cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication
1.10.150.20.9.1.1.1.71	8icuA02	DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding, base-excision repair, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm
1.10.150.20.9.1.1.1.72	8icxA02	DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, base-excision repair, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens
1.10.150.20.9.1.1.1.73	9icaA02	DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, base-excision repair, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens
1.10.150.20.9.1.1.1.74	9icfA02	DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, base-excision repair, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens
1.10.150.20.9.1.1.1.75	9icgA02	DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., base-excision repair, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm
1.10.150.20.9.1.1.1.76	9icnA02	base-excision repair, DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding
1.10.150.20.9.1.1.1.77	9icrA02	Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, base-excision repair, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity
1.10.150.20.9.1.1.1.78	9ictA02	DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., base-excision repair, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm
1.10.150.20.9.1.1.1.79	9icyA02	DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, base-excision repair, cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding
1.10.150.20.9.1.1.1.80	1mq2A02	enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, base-excision repair
1.10.150.20.9.1.1.1.81	1zqgA02	cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, base-excision repair, Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-]
1.10.150.20.9.1.1.1.82	1zqhA02	Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, base-excision repair, DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase.
1.10.150.20.9.1.1.1.83	7icfA02	microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, base-excision repair, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity
1.10.150.20.9.1.1.1.84	7iclA02	DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, base-excision repair, DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens
1.10.150.20.9.1.1.1.85	8icbA02	Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, base-excision repair, cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule
1.10.150.20.9.1.1.1.86	8iclA02	base-excision repair, DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding
1.10.150.20.9.1.1.1.87	8ictA02	base-excision repair, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases.
1.10.150.20.9.1.1.1.88	8icyA02	Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, base-excision repair
1.10.150.20.9.1.1.1.89	8iczA02	DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., base-excision repair, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm
1.10.150.20.9.1.1.1.90	9iccA02	DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, base-excision repair, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens
1.10.150.20.9.1.1.1.91	9iciA02	enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, base-excision repair
1.10.150.20.9.1.1.1.92	9icjA02	DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding, base-excision repair, DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm
1.10.150.20.9.1.1.1.93	9icpA02	Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, base-excision repair
1.10.150.20.9.1.1.1.94	1zqaA02	cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, base-excision repair, enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-]
1.10.150.20.9.1.1.1.95	1zqbA02	DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., base-excision repair, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm
1.10.150.20.9.1.1.1.96	1zqcA02	DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, base-excision repair, cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair
1.10.150.20.9.1.1.1.97	1zqkA02	Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding, DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., base-excision repair, cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule
1.10.150.20.9.1.1.1.98	1zqmA02	base-excision repair, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding
1.10.150.20.9.1.1.1.99	1zqoA02	microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, base-excision repair, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity
1.10.150.20.9.1.1.1.100	8iceA02	DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., base-excision repair, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm
1.10.150.20.9.1.1.1.101	8icjA02	Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, base-excision repair, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity
1.10.150.20.9.1.1.1.102	8icvA02	base-excision repair, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases.
1.10.150.20.9.1.1.1.103	9icbA02	lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, base-excision repair, cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair
1.10.150.20.9.1.1.1.104	1zqjA02	base-excision repair, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases.
1.10.150.20.9.1.1.1.105	1zqlA02	base-excision repair, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases.
1.10.150.20.9.1.1.1.106	1zqqA02	Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, base-excision repair, cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication
1.10.150.20.9.1.1.1.107	1zqsA02	DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, base-excision repair, cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair
1.10.150.20.9.1.1.1.108	7icoA02	Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., base-excision repair
1.10.150.20.9.1.1.1.109	7icuA02	DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, base-excision repair, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens
1.10.150.20.9.1.1.1.110	8icgA02	enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, base-excision repair
1.10.150.20.9.1.1.1.111	8ichA02	lyase activity, DNA-directed DNA polymerase., DNA-directed DNA polymerase activity, base-excision repair, cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair
1.10.150.20.9.1.1.1.112	8icwA02	cytoplasm, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, base-excision repair, enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-]
1.10.150.20.9.1.1.1.113	9iceA02	DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity, base-excision repair, cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], enzyme binding, Other carbon-oxygen lyases., microtubule binding, Base excision repair
1.10.150.20.9.1.1.1.114	1zqtA02	Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding, DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., base-excision repair, cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication
1.10.150.20.9.1.1.1.115	1zqdA02	DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., base-excision repair, cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding
1.10.150.20.9.1.1.1.116	7icjA02	Homo sapiens, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Other carbon-oxygen lyases., enzyme binding, Base excision repair, microtubule binding, DNA-directed DNA polymerase activity, lyase activity, DNA-directed DNA polymerase., base-excision repair, cytoplasm, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication
1.10.150.20.9.1.1.1.117	1zqeA02	base-excision repair, DNA-directed DNA polymerase activity, DNA-directed DNA polymerase., lyase activity, spindle microtubule, DNA polymerase beta, DNA-dependent DNA replication, cytoplasm, DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, Base excision repair, microtubule binding, Other carbon-oxygen lyases., enzyme binding
1.10.150.20.9.1.1.1.118	1zqrA02	microtubule binding, Base excision repair, enzyme binding, Other carbon-oxygen lyases., DNA polymerase beta subunit [EC:2.7.7.7 4.2.99.-], Homo sapiens, DNA polymerase beta, DNA-dependent DNA replication, spindle microtubule, cytoplasm, base-excision repair, DNA-directed DNA polymerase., lyase activity, DNA-directed DNA polymerase activity

The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:

Multiple alignments for each functional family
Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
Detailed functional information on diversity and conservation within Functional families
Multi-domain architectures

In the meantime, please find a summary of information on the FunFams and protein networks within this superfamily on the Gene3D pages:

http://gene3d.biochem.ucl.ac.uk/superfamily/?accession=1.10.150.20.9.1.1.1

What is a Non-Redundant Representative?

Why can't I have a multiple structural alignment of the whole superfamily?

The simple answer is that some of the larger superfamilies in CATH comprise relatives which are very structurally diverse, having different secondary structure embellishments. Attempting to provide a global alignment of all domains in the superfamily would result in poor quality alignments. As a result, structural alignments in CATH are generated by first clustering together the structures that have at least some recognisable structural similarity using a normalised RMSD score (SIMAX = RMSDxNumber of residues in the largest domain/number of aligned residues) less than a given cutoff.

What is an Close Structural Cluster?

A Close Structural Cluster describes a cluster of two or more CATH domains that have been grouped together due to their close structural similarity (SIMAX score < 5Å where SIMAX = RMSD x Number of residues in the larger domain/number of aligned residues).

What is a Distant Structural Cluster?

A Distant Structural Cluster describes a cluster of two or CATH domains that have been grouped together with a more relaxed structural similarity threshold to investigate more distant evolutionary similarities (SIMAX score < 5Å where SIMAX = RMSD x Number of residues in the larger domain/number of aligned residues).

What is a Structural Neighbour?

The term "structural neighbour" is used here to describe two CATH domains that share a degree of structural similarity. The SSAP algorithm is used to calculate this similarity and works by generating a structure-based pairwise alignment of the two domains then scoring this alignment using a RMSD score which has been normalised by the length of the larger domain divided by the number of aligned residues (SIMAX).

S100 Family: 1.10.150.20.9.1.1.1

Classification Lineage (1.10.150.20.9.1.1.1)

Summary of Non-Redundant Representatives

What is a Non-Redundant Representative?

S100 Count Entries in S100 Family 1.10.150.20.9.1.1.1 (118)

What is a Non-Redundant Representative?

Why can't I have a multiple structural alignment of the whole superfamily?

What is an Close Structural Cluster?

What is a Distant Structural Cluster?

What is a Structural Neighbour?

CATH Shortcuts