S100 Family: 1.10.10.60.66.1.1.1
Representative domain: 1iv6A00
Classification Lineage (1.10.10.60.66.1.1.1)
| CATH Code | Level Description | Links |
|---|---|---|
 1
| Mainly Alpha | |
 1.10
| Orthogonal Bundle | |
 1.10.10
| Arc Repressor Mutant, subunit A | |
 1.10.10.60
| Homeodomain-like | Gene3D |
 1.10.10.60.66
| ||
 1.10.10.60.66.1
| ||
 1.10.10.60.66.1.1
| ||
 1.10.10.60.66.1.1.1
|
Summary of Non-Redundant Representatives
| | | | | | | |  |
|---|---|---|---|---|---|---|---|---|
| - | - | - | - | - | - | - | - | 2 |
S100 Count Entries in S100 Family 1.10.10.60.66.1.1.1 (2)
| CATH Level | CATH code | Domain ID | Keywords | Thumbnail |
|---|---|---|---|---|
|
1.10.10.60.66.1.1.1.1 | 1iv6A00 | Telomeric repeat-binding factor 1, telomere maintenance via telomere shortening, Homo sapiens, chromosome, telomeric region, positive regulation of mitosis, positive regulation of microtubule polymerization, negative regulation of telomerase activity, G2/M transition of mitotic cell cycle, nuclear telomere cap complex, telomere maintenance via telomerase, age-dependent telomere shortening, caspase activator activity, double-stranded telomeric DNA binding, protein homodimerization activity, protein homooligomerization, mitotic cell cycle spindle assembly checkpoint, microtubule binding, positive regulation of mitotic cell cycle, telomeric DNA binding, negative regulation of telomere maintenance via telomerase, DNA bending activity, protein heterodimerization activity, induction of apoptosis, activation of caspase activity, nucleus, telomerase inhibitor activity | |
|
1.10.10.60.66.1.1.1.2 | 1ityA00 | negative regulation of telomere maintenance via telomerase, telomeric DNA binding, positive regulation of mitotic cell cycle, telomerase inhibitor activity, nucleus, activation of caspase activity, induction of apoptosis, protein heterodimerization activity, DNA bending activity, telomere maintenance via telomerase, nuclear telomere cap complex, G2/M transition of mitotic cell cycle, positive regulation of microtubule polymerization, negative regulation of telomerase activity, positive regulation of mitosis, telomere maintenance via telomere shortening, Homo sapiens, chromosome, telomeric region, Telomeric repeat-binding factor 1, microtubule binding, mitotic cell cycle spindle assembly checkpoint, protein homooligomerization, age-dependent telomere shortening, caspase activator activity, protein homodimerization activity, double-stranded telomeric DNA binding |
The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
- Multiple alignments for each functional family
- Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
- Detailed functional information on diversity and conservation within Functional families
- Multi-domain architectures