S100 Family: 1.10.10.60.19.1.1.1
Representative domain: 1w0tA00
Classification Lineage (1.10.10.60.19.1.1.1)
| CATH Code | Level Description | Links |
|---|---|---|
 1
| Mainly Alpha | |
 1.10
| Orthogonal Bundle | |
 1.10.10
| Arc Repressor Mutant, subunit A | |
 1.10.10.60
| Homeodomain-like | Gene3D |
 1.10.10.60.19
| ||
 1.10.10.60.19.1
| ||
 1.10.10.60.19.1.1
| ||
 1.10.10.60.19.1.1.1
|
Summary of Non-Redundant Representatives
| | | | | | | |  |
|---|---|---|---|---|---|---|---|---|
| - | - | - | - | - | - | - | - | 2 |
S100 Count Entries in S100 Family 1.10.10.60.19.1.1.1 (2)
| CATH Level | CATH code | Domain ID | Keywords | Thumbnail |
|---|---|---|---|---|
|
1.10.10.60.19.1.1.1.1 | 1w0tA00 | telomerase inhibitor activity, nucleus, activation of caspase activity, induction of apoptosis, protein heterodimerization activity, DNA bending activity, telomeric DNA binding, negative regulation of telomere maintenance via telomerase, positive regulation of mitotic cell cycle, microtubule binding, mitotic cell cycle spindle assembly checkpoint, protein homooligomerization, double-stranded telomeric DNA binding, protein homodimerization activity, age-dependent telomere shortening, caspase activator activity, telomere maintenance via telomerase, nuclear telomere cap complex, G2/M transition of mitotic cell cycle, negative regulation of telomerase activity, positive regulation of mitosis, positive regulation of microtubule polymerization, Homo sapiens, chromosome, telomeric region, telomere maintenance via telomere shortening, Telomeric repeat-binding factor 1 | |
|
1.10.10.60.19.1.1.1.2 | 1w0tB00 | negative regulation of telomere maintenance via telomerase, telomeric DNA binding, positive regulation of mitotic cell cycle, activation of caspase activity, nucleus, telomerase inhibitor activity, DNA bending activity, protein heterodimerization activity, induction of apoptosis, G2/M transition of mitotic cell cycle, nuclear telomere cap complex, telomere maintenance via telomerase, Telomeric repeat-binding factor 1, telomere maintenance via telomere shortening, Homo sapiens, chromosome, telomeric region, positive regulation of microtubule polymerization, positive regulation of mitosis, negative regulation of telomerase activity, microtubule binding, caspase activator activity, age-dependent telomere shortening, protein homodimerization activity, double-stranded telomeric DNA binding, protein homooligomerization, mitotic cell cycle spindle assembly checkpoint |
The information on Functional Families (FunFams) is currently being updated and will be released by the end of March 2012. The pages will include the following features:
- Multiple alignments for each functional family
- Representative structure for each functional with known catalytic and interface residues highlighted, along with conserved residues predicted by scorecons
- Detailed functional information on diversity and conservation within Functional families
- Multi-domain architectures