CATH Domain 3zl7C00

CATH Classification

Level	CATH Code	Description
	2	Mainly Beta
	2.30	Roll
	2.30.30	SH3 type barrels.
	2.30.30.40	SH3 Domains

Domain Context

CATH Clusters

Superfamily	SH3 Domains
Functional Family	Tyrosine-protein kinase Fyn

Enzyme Information

UniProtKB Entries (1)

BACE2_HUMAN

Homo sapiens

Beta-secretase 2

PDB Structure

PDB	3ZL7
External Links	PDBSum Proteopedia
Method	X-RAY DIFFRACTION
Organism
Primary Citation	Mapping the Conformational Space Accessible to Bace2 Using Surface Mutants and Co-Crystals with Fab-Fragments, Fynomers, and Xaperones Banner, D.W., Gsell, B., Benz, J., Bertschinger, J., Burger, D., Brack, S., Cuppuleri, S., Debulpaep, M., Gast, A., Grabulovski, D., Hennig, M., Hilpert, H., Huber, W., Kuglstatter, A., Kusznir, E., Laeremans, T., Matile, H., Miscenic, C., Rufer, A., Schlatter, D., Steyeart, J., Stihle, M., Thoma, R., Weber, M., Ruf, A. Acta Crystallogr.,Sect.D