The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

"
Medium-chain alcohol dehydrogenases, catalytic domain
".

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.
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FunFam 1: S-(hydroxymethyl)glutathione dehydrogenase

Please note: GO annotations are assigned to the full protein sequence rather than individual protein domains. Since a given protein can contain multiple domains, it is possible that some of the annotations below come from additional domains that occur in the same protein, but have been classified elsewhere in CATH.

There are 59 GO terms relating to "molecular function"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Alcohol dehydrogenase (NAD) activity GO:0004022
Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
20 P00326 (/IDA) P00329 (/IDA) P00329 (/IDA) P06757 (/IDA) P08319 (/IDA) P12711 (/IDA) P28474 (/IDA) P28474 (/IDA) P32771 (/IDA) P32771 (/IDA)
(10 more)
Formaldehyde dehydrogenase activity GO:0018467
Catalysis of the reaction: formaldehyde + H(2)O + NAD(+) = formate + 2 H(+) + NADH.
11 P46415 (/ISS) Q9HY01 (/ISS) Q9HY01 (/ISS) Q9HY01 (/ISS) Q9HY01 (/ISS) Q9HY01 (/ISS) Q9HY01 (/ISS) Q9HY01 (/ISS) Q9HY01 (/ISS) Q9HY01 (/ISS)
(1 more)
Alcohol dehydrogenase (NAD) activity GO:0004022
Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
8 O74540 (/ISO) P00329 (/ISO) P00329 (/ISO) P28474 (/ISO) P28474 (/ISO) Q64437 (/ISO) Q64437 (/ISO) Q9QYY9 (/ISO)
Alcohol dehydrogenase activity, zinc-dependent GO:0004024
Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of zinc.
8 P00325 (/IDA) P00325 (/IDA) P00325 (/IDA) P07327 (/IDA) P08319 (/IDA) P25437 (/IDA) P40394 (/IDA) Q9QYY9 (/IDA)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
8 P00325 (/IDA) P00325 (/IDA) P00325 (/IDA) P08319 (/IDA) P11766 (/IDA) P11766 (/IDA) P25437 (/IDA) P41682 (/IDA)
Alcohol dehydrogenase (NAD) activity GO:0004022
Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
7 P00329 (/TAS) P00329 (/TAS) P06757 (/TAS) P40394 (/TAS) P41682 (/TAS) Q64437 (/TAS) Q64437 (/TAS)
Retinol dehydrogenase activity GO:0004745
Catalysis of the reaction: retinol + NAD+ = retinal + NADH + H+.
5 P06757 (/IDA) P08319 (/IDA) P40394 (/IDA) Q64437 (/IDA) Q64437 (/IDA)
Retinol dehydrogenase activity GO:0004745
Catalysis of the reaction: retinol + NAD+ = retinal + NADH + H+.
5 P00329 (/ISO) P00329 (/ISO) Q64437 (/ISO) Q64437 (/ISO) Q9QYY9 (/ISO)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
5 P28474 (/ISO) P28474 (/ISO) Q64437 (/ISO) Q64437 (/ISO) Q9QYY9 (/ISO)
Ethanol binding GO:0035276
Interacting selectively and non-covalently with ethanol, CH(3)-CH(2)-OH.
5 P00329 (/ISO) P00329 (/ISO) Q64437 (/ISO) Q64437 (/ISO) Q9QYY9 (/ISO)
NAD binding GO:0051287
Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
5 P00329 (/ISO) P00329 (/ISO) Q64437 (/ISO) Q64437 (/ISO) Q9QYY9 (/ISO)
S-(hydroxymethyl)glutathione dehydrogenase activity GO:0051903
Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+.
5 F4K7D6 (/IDA) P25437 (/IDA) P32771 (/IDA) P32771 (/IDA) P46415 (/IDA)
Formaldehyde dehydrogenase activity GO:0018467
Catalysis of the reaction: formaldehyde + H(2)O + NAD(+) = formate + 2 H(+) + NADH.
4 P11766 (/IDA) P11766 (/IDA) Q7T2J4 (/IDA) Q8J0F1 (/IDA)
Ethanol binding GO:0035276
Interacting selectively and non-covalently with ethanol, CH(3)-CH(2)-OH.
4 P06757 (/IDA) P40394 (/IDA) P41682 (/IDA) Q64563 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
4 P00329 (/IPI) P00329 (/IPI) P28474 (/IPI) P28474 (/IPI)
NAD binding GO:0051287
Interacting selectively and non-covalently with nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions; binding may be to either the oxidized form, NAD+, or the reduced form, NADH.
4 P06757 (/IDA) P08319 (/IDA) P41682 (/IDA) Q64563 (/IDA)
Alcohol dehydrogenase activity, zinc-dependent GO:0004024
Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of zinc.
3 Q64437 (/ISO) Q64437 (/ISO) Q9QYY9 (/ISO)
Retinol binding GO:0019841
Interacting selectively and non-covalently with retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation.
3 P08319 (/IDA) P40394 (/IDA) P41682 (/IDA)
Retinol binding GO:0019841
Interacting selectively and non-covalently with retinol, vitamin A1, 2,6,6-trimethyl-1-(9'-hydroxy-3',7'-dimethylnona-1',3',5',7'-tetraenyl)cyclohex-1-ene, one of the three components that makes up vitamin A. Retinol is an intermediate in the vision cycle and it also plays a role in growth and differentiation.
3 Q64437 (/ISO) Q64437 (/ISO) Q9QYY9 (/ISO)
Alcohol dehydrogenase (NAD) activity GO:0004022
Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
2 P32771 (/IMP) P32771 (/IMP)
Alcohol dehydrogenase (NAD) activity GO:0004022
Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+.
2 Q5AVP8 (/RCA) Q5AVP8 (/RCA)
Alcohol dehydrogenase activity, zinc-dependent GO:0004024
Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of zinc.
2 Q54TC2 (/ISS) Q8EFC7 (/ISS)
Aldehyde oxidase activity GO:0004031
Catalysis of the reaction: an aldehyde + H2O + O2 = a carboxylic acid + hydrogen peroxide.
2 Q64437 (/ISO) Q64437 (/ISO)
Fatty acid binding GO:0005504
Interacting selectively and non-covalently with fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
2 P11766 (/IDA) P11766 (/IDA)
Fatty acid binding GO:0005504
Interacting selectively and non-covalently with fatty acids, aliphatic monocarboxylic acids liberated from naturally occurring fats and oils by hydrolysis.
2 P28474 (/ISO) P28474 (/ISO)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
2 P00329 (/ISO) P00329 (/ISO)
Zinc ion binding GO:0008270
Interacting selectively and non-covalently with zinc (Zn) ions.
2 Q54TC2 (/ISS) Q8EFC7 (/ISS)
Electron transfer activity GO:0009055
Any molecular entity that serves as an electron acceptor and electron donor in an electron transport chain. An electron transport chain is a process in which a series of electron carriers operate together to transfer electrons from donors to any of several different terminal electron acceptors to generate a transmembrane electrochemical gradient.
2 P11766 (/TAS) P11766 (/TAS)
Oxidoreductase activity GO:0016491
Catalysis of an oxidation-reduction (redox) reaction, a reversible chemical reaction in which the oxidation state of an atom or atoms within a molecule is altered. One substrate acts as a hydrogen or electron donor and becomes oxidized, while the other acts as hydrogen or electron acceptor and becomes reduced.
2 Q64437 (/TAS) Q64437 (/TAS)
Formaldehyde dehydrogenase activity GO:0018467
Catalysis of the reaction: formaldehyde + H(2)O + NAD(+) = formate + 2 H(+) + NADH.
2 P28474 (/ISO) P28474 (/ISO)
Hydroxymethylfurfural reductase (NADH) activity GO:0033833
Catalysis of the reaction: 5-hydroxymethylfurfural + NADH + H+ = 2,5-bis-hydroxymethylfuran + NAD+.
2 P32771 (/IMP) P32771 (/IMP)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 P41682 (/IDA) Q8J0F1 (/IDA)
Protein homodimerization activity GO:0042803
Interacting selectively and non-covalently with an identical protein to form a homodimer.
2 Q64437 (/ISO) Q64437 (/ISO)
Receptor antagonist activity GO:0048019
The activity of a gene product that interacts with a receptor to decrease the ability of the receptor agonist to bind and activate the receptor.
2 Q64437 (/ISO) Q64437 (/ISO)
S-(hydroxymethyl)glutathione dehydrogenase activity GO:0051903
Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+.
2 P28474 (/IMP) P28474 (/IMP)
S-(hydroxymethyl)glutathione dehydrogenase activity GO:0051903
Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+.
2 O74540 (/ISO) P78870 (/ISO)
S-(hydroxymethyl)glutathione dehydrogenase activity GO:0051903
Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+.
2 Q5AVP8 (/RCA) Q5AVP8 (/RCA)
S-(hydroxymethyl)glutathione dehydrogenase activity GO:0051903
Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+.
2 P11766 (/TAS) P11766 (/TAS)
S-nitrosoglutathione reductase activity GO:0080007
Catalysis of the reaction: glutathione N-hydroxysulfenamide + NADH + H+ = S-nitrosoglutathione + NAD+.
2 F4K7D6 (/IMP) P46415 (/IMP)
NADPH:quinone reductase activity GO:0003960
Catalysis of the reaction: NADPH + H+ + quinone = NADP+ + semiquinone.
1 Q9QYY9 (/IDA)
NADPH:quinone reductase activity GO:0003960
Catalysis of the reaction: NADPH + H+ + quinone = NADP+ + semiquinone.
1 P08319 (/ISS)
Alcohol dehydrogenase activity, zinc-dependent GO:0004024
Catalysis of the reaction: an alcohol + NAD+ = an aldehyde or ketone + NADH + H+, requiring the presence of zinc.
1 Q17335 (/NAS)
Aldehyde oxidase activity GO:0004031
Catalysis of the reaction: an aldehyde + H2O + O2 = a carboxylic acid + hydrogen peroxide.
1 P40394 (/IDA)
Alditol:NADP+ 1-oxidoreductase activity GO:0004032
Catalysis of the reaction: an alditol + NADP+ = an aldose + NADPH + H+.
1 Q9QYY9 (/IDA)
Octanol dehydrogenase activity GO:0004552
Catalysis of the reaction: 1-octanol + NAD(+) = 1-octanal + H(+) + NADH.
1 P46415 (/IDA)
All-trans retinal binding GO:0005503
Interacting selectively and non-covalently with all-trans retinal, a compound that plays an important role in the visual process in most vertebrates. All-trans retinal (trans r., visual yellow) results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal is one of the forms of vitamin A.
1 P08319 (/IDA)
All-trans retinal binding GO:0005503
Interacting selectively and non-covalently with all-trans retinal, a compound that plays an important role in the visual process in most vertebrates. All-trans retinal (trans r., visual yellow) results from the bleaching of rhodopsin by light, in which the 11-cis form is converted to the all-trans form. Retinal is one of the forms of vitamin A.
1 Q9QYY9 (/ISO)
Protein binding GO:0005515
Interacting selectively and non-covalently with any protein or protein complex (a complex of two or more proteins that may include other nonprotein molecules).
1 P07327 (/IPI)
Drug binding GO:0008144
Interacting selectively and non-covalently with a drug, any naturally occurring or synthetic substance, other than a nutrient, that, when administered or applied to an organism, affects the structure or functioning of the organism; in particular, any such substance used in the diagnosis, prevention, or treatment of disease.
1 P06757 (/IPI)
Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620
Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces NAD or NADP.
1 P08319 (/IDA)
Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor GO:0016620
Catalysis of an oxidation-reduction (redox) reaction in which an aldehyde or ketone (oxo) group acts as a hydrogen or electron donor and reduces NAD or NADP.
1 Q9QYY9 (/ISO)
Benzaldehyde dehydrogenase activity GO:0019115
Catalysis of the reaction: benzaldehyde + NAD(P)+ + H2O = benzoate + NAD(P)H + H+.
1 P08319 (/IDA)
Benzaldehyde dehydrogenase activity GO:0019115
Catalysis of the reaction: benzaldehyde + NAD(P)+ + H2O = benzoate + NAD(P)H + H+.
1 Q9QYY9 (/ISO)
Hydroxymethylfurfural reductase (NADH) activity GO:0033833
Catalysis of the reaction: 5-hydroxymethylfurfural + NADH + H+ = 2,5-bis-hydroxymethylfuran + NAD+.
1 O74540 (/ISO)
Identical protein binding GO:0042802
Interacting selectively and non-covalently with an identical protein or proteins.
1 P25437 (/IPI)
Glutathione binding GO:0043295
Interacting selectively and non-covalently with glutathione; a tripeptide composed of the three amino acids cysteine, glutamic acid and glycine.
1 Q8J0F1 (/IDA)
Receptor antagonist activity GO:0048019
The activity of a gene product that interacts with a receptor to decrease the ability of the receptor agonist to bind and activate the receptor.
1 P40394 (/IDA)
S-(hydroxymethyl)glutathione dehydrogenase activity GO:0051903
Catalysis of the reaction: S-(hydroxymethyl)glutathione + NAD(P)+ = S-formylglutathione + NAD(P)H + H+.
1 Q17335 (/NAS)
NAD+ binding GO:0070403
Interacting selectively and non-covalently with the oxidized form, NAD, of nicotinamide adenine dinucleotide, a coenzyme involved in many redox and biosynthetic reactions.
1 Q8J0F1 (/IDA)

There are 83 GO terms relating to "biological process"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Formaldehyde catabolic process GO:0046294
The chemical reactions and pathways resulting in the breakdown of formaldehyde (methanal, H2C=O), the simplest aldehyde.
10 Q9HY01 (/ISS) Q9HY01 (/ISS) Q9HY01 (/ISS) Q9HY01 (/ISS) Q9HY01 (/ISS) Q9HY01 (/ISS) Q9HY01 (/ISS) Q9HY01 (/ISS) Q9HY01 (/ISS) Q9HY01 (/ISS)
Ethanol oxidation GO:0006069
An ethanol metabolic process in which ethanol is converted to acetyl-CoA via acetaldehyde and acetate.
9 P00325 (/TAS) P00325 (/TAS) P00325 (/TAS) P00326 (/TAS) P07327 (/TAS) P08319 (/TAS) P11766 (/TAS) P11766 (/TAS) P40394 (/TAS)
Ethanol oxidation GO:0006069
An ethanol metabolic process in which ethanol is converted to acetyl-CoA via acetaldehyde and acetate.
8 P00325 (/IDA) P00325 (/IDA) P00325 (/IDA) P00326 (/IDA) P06757 (/IDA) P08319 (/IDA) P40394 (/IDA) Q64563 (/IDA)
Alcohol metabolic process GO:0006066
The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
5 P08319 (/IDA) Q4QRI0 (/IDA) Q6P0S5 (/IDA) Q7T2J4 (/IDA) Q90Y38 (/IDA)
Ethanol metabolic process GO:0006067
The chemical reactions and pathways involving ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.
5 P41682 (/IDA) Q4QRI0 (/IDA) Q6P0S5 (/IDA) Q90Y38 (/IDA) Q9QYY9 (/IDA)
Ethanol oxidation GO:0006069
An ethanol metabolic process in which ethanol is converted to acetyl-CoA via acetaldehyde and acetate.
5 P00329 (/ISO) P00329 (/ISO) Q64437 (/ISO) Q64437 (/ISO) Q9QYY9 (/ISO)
Retinoid metabolic process GO:0001523
The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
4 P00329 (/IMP) P00329 (/IMP) P28474 (/IMP) P28474 (/IMP)
Ethanol catabolic process GO:0006068
The chemical reactions and pathways resulting in the breakdown of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.
4 P00329 (/IMP) P00329 (/IMP) Q64437 (/IMP) Q64437 (/IMP)
Retinol metabolic process GO:0042572
The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A.
4 P00329 (/IMP) P00329 (/IMP) Q64437 (/IMP) Q64437 (/IMP)
Retinoic acid metabolic process GO:0042573
The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A.
4 P00329 (/IMP) P00329 (/IMP) Q64437 (/IMP) Q64437 (/IMP)
Retinoid metabolic process GO:0001523
The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
3 Q64437 (/ISO) Q64437 (/ISO) Q9QYY9 (/ISO)
Ethanol catabolic process GO:0006068
The chemical reactions and pathways resulting in the breakdown of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.
3 P00329 (/IDA) P00329 (/IDA) P12711 (/IDA)
Retinol metabolic process GO:0042572
The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A.
3 Q64437 (/ISO) Q64437 (/ISO) Q9QYY9 (/ISO)
Formaldehyde catabolic process GO:0046294
The chemical reactions and pathways resulting in the breakdown of formaldehyde (methanal, H2C=O), the simplest aldehyde.
3 P32771 (/IDA) P32771 (/IDA) Q8J0F1 (/IDA)
Formaldehyde catabolic process GO:0046294
The chemical reactions and pathways resulting in the breakdown of formaldehyde (methanal, H2C=O), the simplest aldehyde.
3 P25437 (/IMP) P28474 (/IMP) P28474 (/IMP)
Cellular response to xenobiotic stimulus GO:0071466
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a xenobiotic compound stimulus. Xenobiotic compounds are compounds foreign to living organisms.
3 Q4QRI0 (/IDA) Q6P0S5 (/IDA) Q90Y38 (/IDA)
Amino acid catabolic process to alcohol via Ehrlich pathway GO:0000947
The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.
2 P32771 (/IGI) P32771 (/IGI)
Retinoid metabolic process GO:0001523
The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
2 P08319 (/IDA) P40394 (/IDA)
Respiratory system process GO:0003016
A process carried out by the organs or tissues of the respiratory system. The respiratory system is an organ system responsible for respiratory gaseous exchange.
2 P28474 (/IMP) P28474 (/IMP)
Alcohol metabolic process GO:0006066
The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
2 P07327 (/NAS) Q17335 (/NAS)
Alcohol metabolic process GO:0006066
The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
2 Q5AVP8 (/RCA) Q5AVP8 (/RCA)
Ethanol metabolic process GO:0006067
The chemical reactions and pathways involving ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.
2 Q64437 (/ISO) Q64437 (/ISO)
Ethanol catabolic process GO:0006068
The chemical reactions and pathways resulting in the breakdown of ethanol, CH3-CH2-OH, a colorless, water-miscible, flammable liquid produced by alcoholic fermentation.
2 P28474 (/ISO) P28474 (/ISO)
Glycerol metabolic process GO:0006071
The chemical reactions and pathways involving glycerol, 1,2,3-propanetriol, a sweet, hygroscopic, viscous liquid, widely distributed in nature as a constituent of many lipids.
2 Q5AVP8 (/RCA) Q5AVP8 (/RCA)
Cellular aldehyde metabolic process GO:0006081
The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells.
2 P08319 (/IDA) Q9QYY9 (/IDA)
Pyruvate metabolic process GO:0006090
The chemical reactions and pathways involving pyruvate, 2-oxopropanoate.
2 Q5AVP8 (/RCA) Q5AVP8 (/RCA)
Glycine catabolic process GO:0006546
The chemical reactions and pathways resulting in the breakdown of glycine, aminoethanoic acid.
2 A0A1D8PU61 (/NAS) A0A1D8PU61 (/NAS)
Aging GO:0007568
A developmental process that is a deterioration and loss of function over time. Aging includes loss of functions such as resistance to disease, homeostasis, and fertility, as well as wear and tear. Aging includes cellular senescence, but is more inclusive. May precede death and may succeed developmental maturation (GO:0021700).
2 P12711 (/IEP) Q64563 (/IEP)
Pathogenesis GO:0009405
The set of specific processes that generate the ability of an organism to induce an abnormal, generally detrimental state in another organism.
2 A0A1D8PU61 (/IMP) A0A1D8PU61 (/IMP)
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
2 Q64437 (/ISO) Q64437 (/ISO)
Fatty acid omega-oxidation GO:0010430
A fatty acid oxidation process in which the methyl group at the end of the fatty acid molecule (the omega carbon) is first oxidized to a hydroxyl group, then to an oxo group, and finally to a carboxyl group. The long chain dicarboxylates derived from omega-oxidation then enter the beta-oxidation pathway for further degradation.
2 Q64437 (/ISO) Q64437 (/ISO)
Methanol metabolic process GO:0015945
The chemical reactions and pathways involving methanol, CH3-OH, a colorless, flammable, mobile, poisonous liquid, widely used as a solvent.
2 P72324 (/IMP) P72324 (/IMP)
Peptidyl-cysteine S-nitrosylation GO:0018119
The covalent addition of a nitric oxide (NO) group to the sulphur (S) atom of a cysteine residue in a protein, to form peptidyl-S-nitrosyl-L-cysteine.
2 P28474 (/IMP) P28474 (/IMP)
Response to lipopolysaccharide GO:0032496
Any process that results in a change in state or activity of an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a lipopolysaccharide stimulus; lipopolysaccharide is a major component of the cell wall of gram-negative bacteria.
2 P28474 (/IMP) P28474 (/IMP)
Response to retinoic acid GO:0032526
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a retinoic acid stimulus.
2 P00329 (/IDA) P00329 (/IDA)
Response to testosterone GO:0033574
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a testosterone stimulus.
2 P00329 (/IDA) P00329 (/IDA)
Oxalate metabolic process GO:0033609
The chemical reactions and pathways involving oxalate, the organic acid ethanedioate.
2 Q5AVP8 (/RCA) Q5AVP8 (/RCA)
Furaldehyde metabolic process GO:0033859
The chemical reactions and pathways involving furaldehyde, a furan ring-containing aldehyde compound which can be formed from the thermal decomposition of biomass.
2 P32771 (/IMP) P32771 (/IMP)
Cellular response to oxidative stress GO:0034599
Any process that results in a change in state or activity of a cell (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of oxidative stress, a state often resulting from exposure to high levels of reactive oxygen species, e.g. superoxide anions, hydrogen peroxide (H2O2), and hydroxyl radicals.
2 A0A1D8PU61 (/IMP) A0A1D8PU61 (/IMP)
Retinol metabolic process GO:0042572
The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A.
2 P08319 (/IDA) P41682 (/IDA)
Retinol metabolic process GO:0042572
The chemical reactions and pathways involving retinol, one of the three compounds that makes up vitamin A.
2 P00329 (/IGI) P00329 (/IGI)
Retinoic acid metabolic process GO:0042573
The chemical reactions and pathways involving retinoic acid, one of the three components that makes up vitamin A.
2 P00329 (/IGI) P00329 (/IGI)
Cell redox homeostasis GO:0045454
Any process that maintains the redox environment of a cell or compartment within a cell.
2 A0A1D8PU61 (/IMP) A0A1D8PU61 (/IMP)
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
2 Q64437 (/ISO) Q64437 (/ISO)
Positive regulation of blood pressure GO:0045777
Any process in which the force of blood traveling through the circulatory system is increased.
2 P28474 (/IMP) P28474 (/IMP)
Acetaldehyde biosynthetic process GO:0046186
The chemical reactions and pathways resulting in the formation of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.
2 P00329 (/ISO) P00329 (/ISO)
Formaldehyde metabolic process GO:0046292
The chemical reactions and pathways involving formaldehyde (methanal, H2C=O), a colorless liquid or gas with a pungent odor, commonly used as a fixative or an antibacterial agent.
2 F4K7D6 (/IDA) Q7T2J4 (/IDA)
Formaldehyde metabolic process GO:0046292
The chemical reactions and pathways involving formaldehyde (methanal, H2C=O), a colorless liquid or gas with a pungent odor, commonly used as a fixative or an antibacterial agent.
2 Q5LKV7 (/ISS) Q5LLS1 (/ISS)
Formaldehyde catabolic process GO:0046294
The chemical reactions and pathways resulting in the breakdown of formaldehyde (methanal, H2C=O), the simplest aldehyde.
2 O74540 (/ISO) P78870 (/ISO)
Behavioral response to ethanol GO:0048149
Any process that results in a change in the behavior of an organism as a result of an ethanol stimulus.
2 P00329 (/IMP) P00329 (/IMP)
Response to steroid hormone GO:0048545
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a steroid hormone stimulus.
2 P00329 (/IDA) P00329 (/IDA)
Response to nitrosative stress GO:0051409
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nitrosative stress stimulus. Nitrosative stress is a state often resulting from exposure to high levels of nitric oxide (NO) or the highly reactive oxidant peroxynitrite, which is produced following interaction of NO with superoxide anions.
2 P28474 (/IMP) P28474 (/IMP)
Response to redox state GO:0051775
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.
2 P11766 (/IDA) P11766 (/IDA)
Response to redox state GO:0051775
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus indicating redox state. Redox state refers to the balance of oxidized versus reduced forms of electron donors and acceptors in an organelle, cell or organ; plastoquinone, glutathione (GSH/GSSG), and nicotinamide nucleotides (NAD+/NADH and NADP+/NADPH) are among the most important.
2 P28474 (/ISO) P28474 (/ISO)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
2 Q64437 (/ISO) Q64437 (/ISO)
Amino acid catabolic process to alcohol via Ehrlich pathway GO:0000947
The chemical reactions and pathways involving the catabolism of amino acids to produce alcohols with one carbon less than the starting amino acid. In S. cerevisiae, this is known to occur for leucine, isoleucine, valine, methionine, phenylalanine, tyrosine, or tryptophan. Often referred to as the Ehrlich pathway, these reactions generally occur during fermentation to produce a variety of alcohols, often collectively referred to as fusel alcohols. Depending on the redox state of the cells, carboxylic acid derivatives may be produced instead of alcohols.
1 O74540 (/ISO)
Retinoid metabolic process GO:0001523
The chemical reactions and pathways involving retinoids, any member of a class of isoprenoids that contain or are derived from four prenyl groups linked head-to-tail. Retinoids include retinol and retinal and structurally similar natural derivatives or synthetic compounds, but need not have vitamin A activity.
1 P41682 (/TAS)
Alcohol metabolic process GO:0006066
The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
1 P46415 (/IC)
Alcohol metabolic process GO:0006066
The chemical reactions and pathways involving alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
1 Q9QYY9 (/ISO)
Octanol metabolic process GO:0006070
The chemical reactions and pathways involving octanol, the 8-carbon alcohol with the formula C8H17OH.
1 Q7T2J4 (/IDA)
Cellular aldehyde metabolic process GO:0006081
The chemical reactions and pathways involving aldehydes, any organic compound with the formula R-CH=O, as carried out by individual cells.
1 Q9QYY9 (/ISO)
Fermentation GO:0006113
The anaerobic enzymatic conversion of organic compounds, especially carbohydrates, coupling the oxidation and reduction of NAD/H and the generation of adenosine triphosphate (ATP).
1 Q8EFC7 (/ISS)
Cell death GO:0008219
Any biological process that results in permanent cessation of all vital functions of a cell. A cell should be considered dead when any one of the following molecular or morphological criteria is met: (1) the cell has lost the integrity of its plasma membrane; (2) the cell, including its nucleus, has undergone complete fragmentation into discrete bodies (frequently referred to as apoptotic bodies). The cell corpse (or its fragments) may be engulfed by an adjacent cell in vivo, but engulfment of whole cells should not be considered a strict criteria to define cell death as, under some circumstances, live engulfed cells can be released from phagosomes (see PMID:18045538).
1 F4K7D6 (/IMP)
Visual learning GO:0008542
Any process in an organism in which a change in behavior of an individual occurs in response to repeated exposure to a visual cue.
1 P46415 (/IMP)
Response to bacterium GO:0009617
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a stimulus from a bacterium.
1 P40394 (/IDA)
Heat acclimation GO:0010286
Any process that increases heat tolerance of an organism in response to high temperatures.
1 F4K7D6 (/IMP)
Fatty acid omega-oxidation GO:0010430
A fatty acid oxidation process in which the methyl group at the end of the fatty acid molecule (the omega carbon) is first oxidized to a hydroxyl group, then to an oxo group, and finally to a carboxyl group. The long chain dicarboxylates derived from omega-oxidation then enter the beta-oxidation pathway for further degradation.
1 P40394 (/IDA)
Drug metabolic process GO:0017144
The chemical reactions and pathways involving a drug, a substance used in the diagnosis, treatment or prevention of a disease; as used here antibiotic substances (see antibiotic metabolism) are considered to be drugs, even if not used in medical or veterinary practice.
1 P07327 (/TAS)
Animal organ regeneration GO:0031100
The regrowth of a lost or destroyed animal organ.
1 P06757 (/IEP)
Response to progesterone GO:0032570
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a progesterone stimulus.
1 P06757 (/IEP)
Furaldehyde metabolic process GO:0033859
The chemical reactions and pathways involving furaldehyde, a furan ring-containing aldehyde compound which can be formed from the thermal decomposition of biomass.
1 O74540 (/ISO)
Ovulation cycle GO:0042698
The type of sexual cycle seen in females, often with physiologic changes in the endometrium that recur at regular intervals during the reproductive years.
1 Q64563 (/IEP)
Pyruvate catabolic process GO:0042867
The chemical reactions and pathways resulting in the breakdown of pyruvate, 2-oxopropanoate.
1 Q8J0F1 (/IDA)
Response to ethanol GO:0045471
Any process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of an ethanol stimulus.
1 P40394 (/IDA)
Alcohol catabolic process GO:0046164
The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
1 Q9QYY9 (/IDA)
Alcohol catabolic process GO:0046164
The chemical reactions and pathways resulting in the breakdown of alcohols, any of a class of compounds containing one or more hydroxyl groups attached to a saturated carbon atom.
1 P08319 (/ISS)
Acetaldehyde biosynthetic process GO:0046186
The chemical reactions and pathways resulting in the formation of acetaldehyde, a colorless, flammable liquid intermediate in the metabolism of alcohol.
1 P06757 (/IDA)
Seed development GO:0048316
The process whose specific outcome is the progression of the seed over time, from its formation to the mature structure. A seed is a propagating organ formed in the sexual reproductive cycle of gymnosperms and angiosperms, consisting of a protective coat enclosing an embryo and food reserves.
1 F4K7D6 (/IMP)
Oxidation-reduction process GO:0055114
A metabolic process that results in the removal or addition of one or more electrons to or from a substance, with or without the concomitant removal or addition of a proton or protons.
1 P40394 (/IDA)
Regulation of nitric oxide metabolic process GO:0080164
Any process that modulates the frequency, rate or extent of the chemical reactions and pathways involving nitric oxide, nitrogen monoxide (NO), a colorless gas only slightly soluble in water.
1 P46415 (/IC)
Quinone metabolic process GO:1901661
The chemical reactions and pathways involving quinone.
1 Q9QYY9 (/IDA)
Quinone metabolic process GO:1901661
The chemical reactions and pathways involving quinone.
1 P08319 (/ISS)
Regulation of peptidyl-cysteine S-nitrosylation GO:2000169
Any process that modulates the frequency, rate or extent of peptidyl-cysteine S-nitrosylation.
1 P46415 (/IMP)

There are 20 GO terms relating to "cellular component"

The search results have been sorted with the annotations that are found most frequently at the top of the list. The results can be filtered by typing text into the search box at the top of the table.
GO Term Annotations Evidence
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
16 A0A0C4DG85 (/IDA) A0A0D9SFB5 (/IDA) D6RHZ6 (/IDA) E9PFG0 (/IDA) E9PFG0 (/IDA) F4K7D6 (/IDA) P00325 (/IDA) P00325 (/IDA) P00325 (/IDA) P00326 (/IDA)
(6 more)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
11 A0A0C4DG85 (/IDA) D6RHZ6 (/IDA) E9PFG0 (/IDA) E9PFG0 (/IDA) P00325 (/IDA) P00325 (/IDA) P00325 (/IDA) P00326 (/IDA) P07327 (/IDA) P40394 (/IDA)
(1 more)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
9 P00325 (/TAS) P00325 (/TAS) P00325 (/TAS) P00326 (/TAS) P07327 (/TAS) P08319 (/TAS) P11766 (/TAS) P11766 (/TAS) P40394 (/TAS)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
7 D6RHZ6 (/IDA) P00325 (/IDA) P00325 (/IDA) P00325 (/IDA) P00326 (/IDA) P07327 (/IDA) V9HW50 (/IDA)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
5 P00329 (/ISO) P00329 (/ISO) Q64437 (/ISO) Q64437 (/ISO) Q9QYY9 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
4 P00329 (/IDA) P00329 (/IDA) P28474 (/IDA) P28474 (/IDA)
Plasma membrane GO:0005886
The membrane surrounding a cell that separates the cell from its external environment. It consists of a phospholipid bilayer and associated proteins.
4 P00329 (/ISO) P00329 (/ISO) Q64437 (/ISO) Q64437 (/ISO)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 A0A0D9SFB5 (/IDA) P08319 (/IDA) P12711 (/IDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
3 P28474 (/ISO) P28474 (/ISO) Q9QYY9 (/ISO)
Cytosol GO:0005829
The part of the cytoplasm that does not contain organelles but which does contain other particulate matter, such as protein complexes.
3 O74540 (/HDA) P25437 (/HDA) P78870 (/HDA)
Nucleus GO:0005634
A membrane-bounded organelle of eukaryotic cells in which chromosomes are housed and replicated. In most cells, the nucleus contains all of the cell's chromosomes except the organellar chromosomes, and is the site of RNA synthesis and processing. In some species, or in specialized cell types, RNA metabolism or DNA replication may be absent.
2 O74540 (/HDA) P78870 (/HDA)
Nucleoplasm GO:0005654
That part of the nuclear content other than the chromosomes or the nucleolus.
2 P00329 (/ISO) P00329 (/ISO)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P32771 (/HDA) P32771 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P12711 (/IDA) P25437 (/IDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
2 P28474 (/ISO) P28474 (/ISO)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 P32771 (/HDA) P32771 (/HDA)
Mitochondrion GO:0005739
A semiautonomous, self replicating organelle that occurs in varying numbers, shapes, and sizes in the cytoplasm of virtually all eukaryotic cells. It is notably the site of tissue respiration.
2 O74540 (/ISO) P78870 (/ISO)
Extracellular exosome GO:0070062
A vesicle that is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane. Extracellular exosomes, also simply called exosomes, have a diameter of about 40-100 nm.
2 P11766 (/HDA) P11766 (/HDA)
Cytoplasm GO:0005737
All of the contents of a cell excluding the plasma membrane and nucleus, but including other subcellular structures.
1 Q17335 (/NAS)
Peroxisome GO:0005777
A small organelle enclosed by a single membrane, and found in most eukaryotic cells. Contains peroxidases and other enzymes involved in a variety of metabolic processes including free radical detoxification, lipid catabolism and biosynthesis, and hydrogen peroxide metabolism.
1 F4K7D6 (/IDA)