# STOCKHOLM 1.0
#=GF ID 3.40.140.20/FF/000008
#=GF DE Bifunctional purine biosynthesis protein PURH
#=GF AC 3.40.140.20/FF/000008
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 58.900
#=GS 5uz0D02/236-382     AC P31939
#=GS 5uz0D02/236-382     OS Homo sapiens
#=GS 5uz0D02/236-382     DE Bifunctional purine biosynthesis protein PURH
#=GS 5uz0D02/236-382     DR CATH; 5uz0; D:227-373; 
#=GS 5uz0D02/236-382     DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; 
#=GS 5uz0C02/236-382     AC P31939
#=GS 5uz0C02/236-382     OS Homo sapiens
#=GS 5uz0C02/236-382     DE Bifunctional purine biosynthesis protein PURH
#=GS 5uz0C02/236-382     DR CATH; 5uz0; C:227-373; 
#=GS 5uz0C02/236-382     DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; 
#=GS 5uz0B02/236-382     AC P31939
#=GS 5uz0B02/236-382     OS Homo sapiens
#=GS 5uz0B02/236-382     DE Bifunctional purine biosynthesis protein PURH
#=GS 5uz0B02/236-382     DR CATH; 5uz0; B:227-373; 
#=GS 5uz0B02/236-382     DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; 
#=GS 5uz0A02/236-382     AC P31939
#=GS 5uz0A02/236-382     OS Homo sapiens
#=GS 5uz0A02/236-382     DE Bifunctional purine biosynthesis protein PURH
#=GS 5uz0A02/236-382     DR CATH; 5uz0; A:227-373; 
#=GS 5uz0A02/236-382     DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; 
#=GS 5uy8D02/236-382     AC P31939
#=GS 5uy8D02/236-382     OS Homo sapiens
#=GS 5uy8D02/236-382     DE Bifunctional purine biosynthesis protein PURH
#=GS 5uy8D02/236-382     DR CATH; 5uy8; D:227-373; 
#=GS 5uy8D02/236-382     DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; 
#=GS 5uy8C02/236-382     AC P31939
#=GS 5uy8C02/236-382     OS Homo sapiens
#=GS 5uy8C02/236-382     DE Bifunctional purine biosynthesis protein PURH
#=GS 5uy8C02/236-382     DR CATH; 5uy8; C:227-373; 
#=GS 5uy8C02/236-382     DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; 
#=GS 5uy8B02/236-382     AC P31939
#=GS 5uy8B02/236-382     OS Homo sapiens
#=GS 5uy8B02/236-382     DE Bifunctional purine biosynthesis protein PURH
#=GS 5uy8B02/236-382     DR CATH; 5uy8; B:227-373; 
#=GS 5uy8B02/236-382     DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; 
#=GS 5uy8A02/236-382     AC P31939
#=GS 5uy8A02/236-382     OS Homo sapiens
#=GS 5uy8A02/236-382     DE Bifunctional purine biosynthesis protein PURH
#=GS 5uy8A02/236-382     DR CATH; 5uy8; A:227-373; 
#=GS 5uy8A02/236-382     DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; 
#=GS 1pl0D03/227-373     AC P31939
#=GS 1pl0D03/227-373     OS Homo sapiens
#=GS 1pl0D03/227-373     DE Bifunctional purine biosynthesis protein PURH
#=GS 1pl0D03/227-373     DR CATH; 1pl0; D:227-373; 
#=GS 1pl0D03/227-373     DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; 
#=GS 1pl0C03/227-373     AC P31939
#=GS 1pl0C03/227-373     OS Homo sapiens
#=GS 1pl0C03/227-373     DE Bifunctional purine biosynthesis protein PURH
#=GS 1pl0C03/227-373     DR CATH; 1pl0; C:227-373; 
#=GS 1pl0C03/227-373     DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; 
#=GS 1pl0B03/227-373     AC P31939
#=GS 1pl0B03/227-373     OS Homo sapiens
#=GS 1pl0B03/227-373     DE Bifunctional purine biosynthesis protein PURH
#=GS 1pl0B03/227-373     DR CATH; 1pl0; B:227-373; 
#=GS 1pl0B03/227-373     DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; 
#=GS 1pl0A03/227-373     AC P31939
#=GS 1pl0A03/227-373     OS Homo sapiens
#=GS 1pl0A03/227-373     DE Bifunctional purine biosynthesis protein PURH
#=GS 1pl0A03/227-373     DR CATH; 1pl0; A:227-373; 
#=GS 1pl0A03/227-373     DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; 
#=GS 1pkxD03/227-373     AC P31939
#=GS 1pkxD03/227-373     OS Homo sapiens
#=GS 1pkxD03/227-373     DE Bifunctional purine biosynthesis protein PURH
#=GS 1pkxD03/227-373     DR CATH; 1pkx; D:227-373; 
#=GS 1pkxD03/227-373     DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; 
#=GS 1pkxC03/227-373     AC P31939
#=GS 1pkxC03/227-373     OS Homo sapiens
#=GS 1pkxC03/227-373     DE Bifunctional purine biosynthesis protein PURH
#=GS 1pkxC03/227-373     DR CATH; 1pkx; C:227-373; 
#=GS 1pkxC03/227-373     DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; 
#=GS 1pkxB03/227-373     AC P31939
#=GS 1pkxB03/227-373     OS Homo sapiens
#=GS 1pkxB03/227-373     DE Bifunctional purine biosynthesis protein PURH
#=GS 1pkxB03/227-373     DR CATH; 1pkx; B:227-373; 
#=GS 1pkxB03/227-373     DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; 
#=GS 1pkxA03/227-373     AC P31939
#=GS 1pkxA03/227-373     OS Homo sapiens
#=GS 1pkxA03/227-373     DE Bifunctional purine biosynthesis protein PURH
#=GS 1pkxA03/227-373     DR CATH; 1pkx; A:227-373; 
#=GS 1pkxA03/227-373     DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; 
#=GS 1p4rB03/227-373     AC P31939
#=GS 1p4rB03/227-373     OS Homo sapiens
#=GS 1p4rB03/227-373     DE Bifunctional purine biosynthesis protein PURH
#=GS 1p4rB03/227-373     DR CATH; 1p4r; B:227-373; 
#=GS 1p4rB03/227-373     DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; 
#=GS 1p4rA03/227-373     AC P31939
#=GS 1p4rA03/227-373     OS Homo sapiens
#=GS 1p4rA03/227-373     DE Bifunctional purine biosynthesis protein PURH
#=GS 1p4rA03/227-373     DR CATH; 1p4r; A:227-373; 
#=GS 1p4rA03/227-373     DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Hominoidea; Hominidae; Homininae; Homo; Homo sapiens; 
#=GS A8IVF0/233-374      AC A8IVF0
#=GS A8IVF0/233-374      OS Chlamydomonas reinhardtii
#=GS A8IVF0/233-374      DE Aminoimidazolecarboximide ribonucleotide transformylase
#=GS A8IVF0/233-374      DR ORG; Eukaryota; Viridiplantae; Chlorophyta; Chlorophyceae; Chlamydomonadales; Chlamydomonadaceae; Chlamydomonas; Chlamydomonas reinhardtii; 
#=GS F1SS25/179-325      AC F1SS25
#=GS F1SS25/179-325      OS Sus scrofa
#=GS F1SS25/179-325      DE Uncharacterized protein
#=GS F1SS25/179-325      DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Suina; Suidae; Sus; Sus scrofa; 
#=GS F6V8M2/225-336      AC F6V8M2
#=GS F6V8M2/225-336      OS Ornithorhynchus anatinus
#=GS F6V8M2/225-336      DE Uncharacterized protein
#=GS F6V8M2/225-336      DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Monotremata; Ornithorhynchidae; Ornithorhynchus; Ornithorhynchus anatinus; 
#=GS A0A3Q1LXU9/201-347  AC A0A3Q1LXU9
#=GS A0A3Q1LXU9/201-347  OS Bos taurus
#=GS A0A3Q1LXU9/201-347  DE Bifunctional purine biosynthesis protein PURH
#=GS A0A3Q1LXU9/201-347  DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Laurasiatheria; Ruminantia; Pecora; Bovidae; Bovinae; Bos; Bos taurus; 
#=GS A0A2K6NP32/197-343  AC A0A2K6NP32
#=GS A0A2K6NP32/197-343  OS Rhinopithecus roxellana
#=GS A0A2K6NP32/197-343  DE Uncharacterized protein
#=GS A0A2K6NP32/197-343  DR ORG; Eukaryota; Metazoa; Chordata; Craniata; Sarcopterygii; Mammalia; Euarchontoglires; Primates; Haplorrhini; Simiiformes; Catarrhini; Cercopithecoidea; Cercopithecidae; Colobinae; Rhinopithecus; Rhinopithecus roxellana; 
#=GF SQ 23
5uz0D02/236-382             PITVLNGA---------PGFINLC--DALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKII----------SREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKP
5uz0C02/236-382             PITVLNGA---------PGFINLC--DALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKII----------SREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKP
5uz0B02/236-382             PITVLNGA---------PGFINLC--DALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKII----------SREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKP
5uz0A02/236-382             PITVLNGA---------PGFINLC--DALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKII----------SREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKP
5uy8D02/236-382             PITVLNGA---------PGFINLC--DALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKII----------SREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKP
5uy8C02/236-382             PITVLNGA---------PGFINLC--DALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKII----------SREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKP
5uy8B02/236-382             PITVLNGA---------PGFINLC--DALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKII----------SREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKP
5uy8A02/236-382             PITVLNGA---------PGFINLC--DALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKII----------SREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKP
1pl0D03/227-373             PITVLNGA---------PGFINLC--DALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKII----------SREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKP
1pl0C03/227-373             PITVLNGA---------PGFINLC--DALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKII----------SREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKP
1pl0B03/227-373             PITVLNGA---------PGFINLC--DALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKII----------SREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKP
1pl0A03/227-373             PITVLNGA---------PGFINLC--DALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKII----------SREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKP
1pkxD03/227-373             PITVLNGA---------PGFINLC--DALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKII----------SREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKP
1pkxC03/227-373             PITVLNGA---------PGFINLC--DALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKII----------SREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKP
1pkxB03/227-373             PITVLNGA---------PGFINLC--DALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKII----------SREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKP
1pkxA03/227-373             PITVLNGA---------PGFINLC--DALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKII----------SREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKP
1p4rB03/227-373             PITVLNGA---------PGFINLC--DALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKII----------SREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKP
1p4rA03/227-373             PITVLNGA---------PGFINLC--DALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISAAYARARGADRMSSFGDFVALSDVCDVPTAKII----------SREVSDGIIAPGYEEEALTILSKKKNGNYCVLQMDQSYKP
#=GR 1p4rA03/227-373    CSA ________---------_______--________________________00__________________________________________________________________----------________________________________________
A8IVF0/233-374              LVVRQAGGTEAAERSSPPPHPHNCPLDADAAYQCCCDYTE----PSCVIVKHTNPCGIASRADLRE--------------------AYRLAVRADPISAFGGIVAFNRPVDAELAREIREFRSPQDNETKMFYEIVIAPGYTPDGLEVL-KGKSKNLRILEA-QPRAP
F1SS25/179-325              PITVLNGA---------PGFINLC--DALNAWQLVKELKEALGIAAAASFKHVSPAGAAVGIPLSEDEAKVCMVHDLYKTLTPVSTAYARARGADRMSSFGDFVALSDVCDVPTAKII----------SREVSDGIVAPGYDDEALKILSKKKNGNYCVLQMDHSYNP
F6V8M2/225-336              PLSVLNGS---------PGFINLC--DALNAWQLVKELKEALGIPAATSFKHVSPAGAAIGVPLSEEEAKVCMVHDLYKNLTPLSTAYARARGADRMSSFGDFIALSDVCDVPTAKII----------SREVS-----------------------------------
A0A3Q1LXU9/201-347          PITVLNGA---------PGFINLC--DALNAWQLVKELKEALGLPAAASFKHVSPAGAAVGIPLSEDEANVCMVYDLYKTLTPVATAYARARGADRMSSFGDFVALSDVCDVPTAKII----------SREVSDGIIAPGYENEALKILSKKKNGNYCVLQMDQSYIP
A0A2K6NP32/197-343          PITVLNGA---------PGFINLC--DALNAWQLVKELKEALGIPAAASFKHVSPAGAAVGIPLSEDEAKVCMVYDLYKTLTPISTAYARARGADRMSSFGDFVALSDVCDVPTAKII----------SREVSDGIIAPGYEKEALTILSKKKNGNYCVLQVDQSYKP
#=GC scorecons              564555950000000009555659009945959555755944448655559956959594555959344444443444434443439955955995696996579665559655975900000000006755543456666324463462636436334643254336
#=GC scorecons_70           ______*__________*_____*__**__*_*___*__*____*_____**__*_*_*____*_*____________________**__*__**_**_**__***____*___**_*___________*______________________________________
#=GC scorecons_80           ______*__________*_____*__**__*_*______*____*_____**__*_*_*____*_*____________________**__*__**__*_**__**_____*___*__*__________________________________________________
#=GC scorecons_90           ______*__________*_____*__**__*_*______*____*_____**__*_*_*____*_*____________________**__*__**__*_**___*_____*___*__*__________________________________________________
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