The name of this superfamily has been modified since the most recent official CATH+ release (v4_3_0). At the point of the last release, this superfamily was named:

Transthyretin/hydroxyisourate hydrolase domain

Functional Families

Overview of the Structural Clusters (SC) and Functional Families within this CATH Superfamily. Clusters with a representative structure are represented by a filled circle.

CATH Classification

CATH Domains (clustered by sequence similarity)

The following diagram provides an overview of the CATH structural domains within this superfamily. Domains have been grouped into S35, S60, S95, S100 clusters which reflect increasingly strict sequence identity cutoffs. For example, all domains grouped into the same S35 cluster are guaranteed to share at least 35% sequence identity.
Click on an individual cluster to view the domains in more detail