# STOCKHOLM 1.0
#=GF ID 1.10.460.10/FF/000005
#=GF DE DNA topoisomerase
#=GF AC 1.10.460.10/FF/000005
#=GF TP FunFam
#=GF DR CATH: v4.3
#=GF DR DOPS: 40.161
#=GS C7J0A2/181-244_504-605      AC C7J0A2
#=GS C7J0A2/181-244_504-605      OS Oryza sativa Japonica Group
#=GS C7J0A2/181-244_504-605      DE DNA topoisomerase 3-alpha
#=GS C7J0A2/181-244_504-605      DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa; 
#=GS C7J0A2/181-244_504-605      DR EC; 5.6.2.2; 
#=GS A0A0R0JHI3/172-235_495-600  AC A0A0R0JHI3
#=GS A0A0R0JHI3/172-235_495-600  OS Glycine max
#=GS A0A0R0JHI3/172-235_495-600  DE DNA topoisomerase
#=GS A0A0R0JHI3/172-235_495-600  DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja; Glycine max; 
#=GS A0A199VUL0/180-243_503-604  AC A0A199VUL0
#=GS A0A199VUL0/180-243_503-604  OS Ananas comosus
#=GS A0A199VUL0/180-243_503-604  DE DNA topoisomerase
#=GS A0A199VUL0/180-243_503-604  DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Bromeliaceae; Bromelioideae; Ananas; Ananas comosus; 
#=GS A0A3B6HPG9/177-240_500-601  AC A0A3B6HPG9
#=GS A0A3B6HPG9/177-240_500-601  OS Triticum aestivum
#=GS A0A3B6HPG9/177-240_500-601  DE DNA topoisomerase
#=GS A0A3B6HPG9/177-240_500-601  DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Pooideae; Triticeae; Triticinae; Triticum; Triticum aestivum; 
#=GS A0A1D6JPP7/167-225_468-569  AC A0A1D6JPP7
#=GS A0A1D6JPP7/167-225_468-569  OS Zea mays
#=GS A0A1D6JPP7/167-225_468-569  DE DNA topoisomerase
#=GS A0A1D6JPP7/167-225_468-569  DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Panicoideae; Andropogoneae; Tripsacinae; Zea; Zea mays; 
#=GS A0A2K2DV21/180-243_503-604  AC A0A2K2DV21
#=GS A0A2K2DV21/180-243_503-604  OS Brachypodium distachyon
#=GS A0A2K2DV21/180-243_503-604  DE DNA topoisomerase
#=GS A0A2K2DV21/180-243_503-604  DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Pooideae; Brachypodieae; Brachypodium; Brachypodium distachyon; 
#=GS A0A0D9VPW5/180-243_503-604  AC A0A0D9VPW5
#=GS A0A0D9VPW5/180-243_503-604  OS Leersia perrieri
#=GS A0A0D9VPW5/180-243_503-604  DE DNA topoisomerase
#=GS A0A0D9VPW5/180-243_503-604  DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Oryzoideae; Oryzeae; Oryzinae; Leersia; Leersia perrieri; 
#=GS A0A453IU34/153-216_476-577  AC A0A453IU34
#=GS A0A453IU34/153-216_476-577  OS Aegilops tauschii subsp. strangulata
#=GS A0A453IU34/153-216_476-577  DE DNA topoisomerase
#=GS A0A453IU34/153-216_476-577  DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Pooideae; Triticeae; Triticinae; Aegilops; Aegilops tauschii; Aegilops tauschii subsp. strangulata; 
#=GS A0A0D3FE73/146-209_469-570  AC A0A0D3FE73
#=GS A0A0D3FE73/146-209_469-570  OS Oryza barthii
#=GS A0A0D3FE73/146-209_469-570  DE DNA topoisomerase
#=GS A0A0D3FE73/146-209_469-570  DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza barthii; 
#=GS A0A0E0NQ39/181-244_504-605  AC A0A0E0NQ39
#=GS A0A0E0NQ39/181-244_504-605  OS Oryza rufipogon
#=GS A0A0E0NQ39/181-244_504-605  DE DNA topoisomerase
#=GS A0A0E0NQ39/181-244_504-605  DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza rufipogon; 
#=GS A0A0E0B042/120-183_443-544  AC A0A0E0B042
#=GS A0A0E0B042/120-183_443-544  OS Oryza glumipatula
#=GS A0A0E0B042/120-183_443-544  DE DNA topoisomerase
#=GS A0A0E0B042/120-183_443-544  DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza glumipatula; 
#=GS J3LKB1/181-244_504-605      AC J3LKB1
#=GS J3LKB1/181-244_504-605      OS Oryza brachyantha
#=GS J3LKB1/181-244_504-605      DE DNA topoisomerase
#=GS J3LKB1/181-244_504-605      DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza brachyantha; 
#=GS I1P7W6/181-244_511-612      AC I1P7W6
#=GS I1P7W6/181-244_511-612      OS Oryza glaberrima
#=GS I1P7W6/181-244_511-612      DE DNA topoisomerase
#=GS I1P7W6/181-244_511-612      DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza glaberrima; 
#=GS A0A0E0GH85/182-245_505-606  AC A0A0E0GH85
#=GS A0A0E0GH85/182-245_505-606  OS Oryza sativa f. spontanea
#=GS A0A0E0GH85/182-245_505-606  DE DNA topoisomerase
#=GS A0A0E0GH85/182-245_505-606  DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa; Oryza sativa f. spontanea; 
#=GS K7KV90/172-235_495-600      AC K7KV90
#=GS K7KV90/172-235_495-600      OS Glycine max
#=GS K7KV90/172-235_495-600      DE DNA topoisomerase
#=GS K7KV90/172-235_495-600      DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja; Glycine max; 
#=GS A0A0R0JNX6/172-235_495-600  AC A0A0R0JNX6
#=GS A0A0R0JNX6/172-235_495-600  OS Glycine max
#=GS A0A0R0JNX6/172-235_495-600  DE DNA topoisomerase
#=GS A0A0R0JNX6/172-235_495-600  DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Fabales; Fabaceae; Papilionoideae; Phaseoleae; Glycine; Soja; Glycine max; 
#=GS A0A3B6IUT6/177-240_500-601  AC A0A3B6IUT6
#=GS A0A3B6IUT6/177-240_500-601  OS Triticum aestivum
#=GS A0A3B6IUT6/177-240_500-601  DE DNA topoisomerase
#=GS A0A3B6IUT6/177-240_500-601  DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Pooideae; Triticeae; Triticinae; Triticum; Triticum aestivum; 
#=GS A0A0E0IGT0/233-296_556-657  AC A0A0E0IGT0
#=GS A0A0E0IGT0/233-296_556-657  OS Oryza sativa f. spontanea
#=GS A0A0E0IGT0/233-296_556-657  DE DNA topoisomerase
#=GS A0A0E0IGT0/233-296_556-657  DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa; Oryza sativa f. spontanea; 
#=GS A0A0E0NQ37/181-244_504-599  AC A0A0E0NQ37
#=GS A0A0E0NQ37/181-244_504-599  OS Oryza rufipogon
#=GS A0A0E0NQ37/181-244_504-599  DE DNA topoisomerase
#=GS A0A0E0NQ37/181-244_504-599  DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza rufipogon; 
#=GS A0A0E0IGT1/233-296_556-657  AC A0A0E0IGT1
#=GS A0A0E0IGT1/233-296_556-657  OS Oryza sativa f. spontanea
#=GS A0A0E0IGT1/233-296_556-657  DE DNA topoisomerase
#=GS A0A0E0IGT1/233-296_556-657  DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza sativa; Oryza sativa f. spontanea; 
#=GS A0A0D9VPW6/180-243_503-604  AC A0A0D9VPW6
#=GS A0A0D9VPW6/180-243_503-604  OS Leersia perrieri
#=GS A0A0D9VPW6/180-243_503-604  DE DNA topoisomerase
#=GS A0A0D9VPW6/180-243_503-604  DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Oryzoideae; Oryzeae; Oryzinae; Leersia; Leersia perrieri; 
#=GS A0A0E0B043/120-183_443-544  AC A0A0E0B043
#=GS A0A0E0B043/120-183_443-544  OS Oryza glumipatula
#=GS A0A0E0B043/120-183_443-544  DE DNA topoisomerase
#=GS A0A0E0B043/120-183_443-544  DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Oryzoideae; Oryzeae; Oryzinae; Oryza; Oryza glumipatula; 
#=GS A0A1D6JPP9/101-157_400-501  AC A0A1D6JPP9
#=GS A0A1D6JPP9/101-157_400-501  OS Zea mays
#=GS A0A1D6JPP9/101-157_400-501  DE DNA topoisomerase
#=GS A0A1D6JPP9/101-157_400-501  DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Panicoideae; Andropogoneae; Tripsacinae; Zea; Zea mays; 
#=GS A0A453IUL8/167-230_490-591  AC A0A453IUL8
#=GS A0A453IUL8/167-230_490-591  OS Aegilops tauschii subsp. strangulata
#=GS A0A453IUL8/167-230_490-591  DE DNA topoisomerase
#=GS A0A453IUL8/167-230_490-591  DR ORG; Eukaryota; Viridiplantae; Streptophyta; Streptophytina; Liliopsida; Petrosaviidae; Poales; Poaceae; Pooideae; Triticeae; Triticinae; Aegilops; Aegilops tauschii; Aegilops tauschii subsp. strangulata; 
#=GF SQ 24
C7J0A2/181-244_504-605              AVDARQEIDLRIGASFTRFQTMLLKDAFVLDDTGDDRNIILSYGPCQFPTLGFIVERFWEIQAHPLLAEADLLGCMDK--AGIGTDATMHDHIKKLLDRCYATKDANTRFSPTNLGEALVMGYD--EMGYELWKPYLRSMMEADMKSVSIGTKSKSEVLENCLQQMKACF
A0A0R0JHI3/172-235_495-600          AVDVRQEIDLRIGASFTRFQTMLMKDAFIIDTATDDRNRVLSYGPCQFPTLGFVVERFWEIQAHPLLSEADLLSYMDREEAKIGTDATMQDHIKKMLDRSYATKDSSTRFTPTNLGEALVLGYDDIDMTYKLWKPDLRSEMEKKMDDVKKGDKSKAEVLVTILQKMEACF
A0A199VUL0/180-243_503-604          AVDARQEIDLRIGASFTRFQTMLLRDAFVLDFAGDERNLVLSYGPCQFPTLGFIVERYWEIQSHPLLSEADLLSCMDK--AGIGTDATMHDHIKKLLDRCYATKDSNTRFSPTNLGEALVMGYD--EMGYELWKPYLRSMMECDMKAVSMGTKRKSEVLENCLQQMKACF
A0A3B6HPG9/177-240_500-601          AVDARQEIDLRIGASFTRFQTMLLKDAFVLDVSGEERNMVLSYGPCQFPTLGFIVERFWEIQAHPLLAEADLLSCMDK--AGIGTDATMHEHIKKLLDRCYATKDANSRFSPTNLGEALVMGYD--EMGYELWKPYLRAMMEADMKSVSVGTKSKAQVLEGCLQQMKACF
A0A1D6JPP7/167-225_468-569          -----YEIDLRIGASFTRFQTMLLKDAFVIDVTGDERSLVLSYGPCQFPTLGFIVERFWEIQAHPLLAEADLLSCMDK--AGIGTDATMHDHIKKLLDRCYATKDENTRFSPTNLGEALVMGYD--EMGYELWKPYLRSMMEADMKSVSVGTKSKSEVLESCLQQMKACF
A0A2K2DV21/180-243_503-604          AVDARQEIDLRIGASFTRFQTMLLKDAFVLDVSGEERNMVLSYGPCQFPTLGFIVERFWEIQAHPLLAEADLLSCMDK--AGIGTDATMHEHIKKLLDRCYATKDANSRFSPTNLGEALVMGYD--EMGYELWKPYLRAMMEADMKAVSIGTKSKLEVLEGCLQQMKACF
A0A0D9VPW5/180-243_503-604          AVDARQEIDLRIGASFTRFQTMLLKDAFVLDDTGDDRNIILSYGPCQFPTLGFIVERFWEIQAHPLLAEADLLSCMDK--AGIGTDATMHDHIKKLLDRSYATKDANTRFSPTNLGEALVMGYD--EMGYELWKPYLRSMMEADMKSVSVGAKSKSEVLENCLQQMKACF
A0A453IU34/153-216_476-577          AVDARQEIDLRIGASFTRFQTMLLKDAFVLDVSGEERNMVLSYGPCQFPTLGFIVERFWEIQAHPLLAEADLLSCMDK--AGIGTDATMHEHIKKLLDRCYATKDANSRFSPTNLGEALVMGYD--EMGYELWKPYLRAMMEADMKSVSVGTKSKAQVLEGCLQQMKACF
A0A0D3FE73/146-209_469-570          AVDARQEIDLRIGASFTRFQTMLLKDAFVLDDTGDDRNIILSYGPCQFPTLGFIVERFWEIQAHPLLAEADLLGCMDK--AGIGTDATMHDHIKKLLDRCYATKDANTRFSPTNLGEALVMGYD--EMGYELWKPYLRSMMEADMKSVSIGTKSKSEVLENCLQQMKACF
A0A0E0NQ39/181-244_504-605          AVDARQEIDLRIGASFTRFQTMLLKDAFVLDDTGDDRNIILSYGPCQFPTLGFIVERFWEIQAHPLLAEADLLGCMDK--AGIGTDATMHDHIKKLLDRCYATKDANTRFSPTNLGEALVMGYD--EMGYELWKPYLRSMMEADMKSVSIGTKSKSEVLENCLQQMKACF
A0A0E0B042/120-183_443-544          AVDARQEIDLRIGASFTRFQTMLLKDAFVLDDTGDDRNIILSYGPCQFPTLGFIVERFWEIQAHPLLAEADLLSCMDK--AGIGTDATMHDHIKKLLDRCYATKDANTRFSPTNLGEALVMGYD--EMGYELWKPYLRSMMEADMKSVSIGTKSKSEVLENCLQQMKACF
J3LKB1/181-244_504-605              AVDARQEIDLRIGASFTRFQTMLLRDAFVLDDTGDERNMILSYGPCQFPTLGFIVERFWEIQAHPLLAEADLLSCMDK--AGIGTDATMHDHIKKLLDRCYATKDANTRFSPTNLGEALVMGYD--EMGYELWKPYLRSMMEADMKSVSIGTKSKAEVLENCLQQMKACF
I1P7W6/181-244_511-612              AVDARQEIDLRIGASFTRFQTMLLKDAFVLDDTGDDRNIILSYGPCQFPTLGFIVERFWEIQAHPLLAEADLLGCMDK--AGIGTDATMHDHIKKLLDRCYATKDANTRFSPTNLGEALVMGYD--EMGYELWKPYLRSMMEADMKSVSIGTKSKSEVLENCLQQMKACF
A0A0E0GH85/182-245_505-606          AVDARQEIDLRIGASFTRFQTMLLKDAFVLDDTGDDRNIILSYGPCQFPTLGFIVERFWEIQAHPLLAEADLLGCMDK--AGIGTDATMHDHIKKLLDRCYATKDANTRFSPTNLGEALVMGYD--EMGYELWKPYLRSMMEADMKSVSIGTKSKSEVLENCLQQMKACF
K7KV90/172-235_495-600              AVDVRQEIDLRIGASFTRFQTMLMKDAFIIDTATDDRNRVLSYGPCQFPTLGFVVERFWEIQAHPLLSEADLLSYMDREEAKIGTDATMQDHIKKMLDRSYATKDSSTRFTPTNLGEALVLGYDDIDMTYKLWKPDLRSEMEKKMDDVKKGDKSKAEVLVTILQKMEACF
A0A0R0JNX6/172-235_495-600          AVDVRQEIDLRIGASFTRFQTMLMKDAFIIDTATDDRNRVLSYGPCQFPTLGFVVERFWEIQAHPLLSEADLLSYMDREEAKIGTDATMQDHIKKMLDRSYATKDSSTRFTPTNLGEALVLGYDDIDMTYKLWKPDLRSEMEKKMDDVKKGDKSKAEVLVTILQKMEACF
A0A3B6IUT6/177-240_500-601          AVDARQEIDLRIGASFTRFQTMLLKDAFVLDVSGEERNMVLSYGPCQFPTLGFIVERFWEIQAHPLLAEADLLSCMDK--AGIGTDATMHEHIKKLLDRCYATKDANSRFSPTNLGEALVMGYD--EMGYELWKPYLRAMMESDMKSVSVGTKSKAQVLEGCLQQMKACF
A0A0E0IGT0/233-296_556-657          AVDARQEIDLRIGASFTRFQTVLLKDAFVLDDTGDDRNIILSYGPCQFPTLGFIVERFWEIQAHPLLAEADLLSCMDK--AGIGTDATMHDHIKKLLDRCYATKNANTRFSPTNLGEALVMGYN--EMGYELWKPYLRSMMEADMKSVSIGTKSKSEVLENCLQQMKACF
A0A0E0NQ37/181-244_504-599          AVDARQEIDLRIGASFTRFQTMLLKDAFVLDDTGDDRNIILSYGPCQFPTLGFIVERFWEIQAHPLLAEADLL--------GIGTDATMHDHIKKLLDRCYATKDANTRFSPTNLGEALVMGYD--EMGYELWKPYLRSMMEADMKSVSIGTKSKSEVLENCLQQMKACF
A0A0E0IGT1/233-296_556-657          AVDARQEIDLRIGASFTRFQTVLLKDAFVLDDTGDDRNIILSYGPCQFPTLGFIVERFWEIQAHPLLAEADLLSCMDK--AGIGTDATMHDHIKKLLDRCYATKNANTRFSPTNLGEALVMGYN--EMGYELWKPYLRSMMEADMKSVSIGTKSKSEVLENCLQQMKACF
A0A0D9VPW6/180-243_503-604          AVDARQEIDLRIGASFTRFQTMLLKDAFVLDDTGDDRNIILSYGPCQFPTLGFIVERFWEIQAHPLLAEADLLSCMDK--AGIGTDATMHDHIKKLLDRSYATKDANTRFSPTNLGEALVMGYD--EMGYELWKPYLRSMMEADMKSVSVGAKSKSEVLENCLQQMKACF
A0A0E0B043/120-183_443-544          AVDARQEIDLRIGASFTRFQTMLLKDAFVLDDTGDDRNIILSYGPCQFPTLGFIVERFWEIQAHPLLAEADLLSCMDK--AGIGTDATMHDHIKKLLDRCYATKDANTRFSPTNLGEALVMGYD--EMGYELWKPYLRSMMEADMKSVSIGTKSKSEVLENCLQQMKACF
A0A1D6JPP9/101-157_400-501          -------IDLRIGASFTRFQTMLLKDAFVIDVTGDERSLVLSYGPCQFPTLGFIVERFWEIQAHPLLAEADLLSCMDK--AGIGTDATMHDHIKKLLDRCYATKDENTRFSPTNLGEALVMGYD--EMGYELWKPYLRSMMEADMKSVSVGTKSKSEVLESCLQQMKACF
A0A453IUL8/167-230_490-591          AVDARQEIDLRIGASFTRFQTMLLKDAFVLDVSGEERNMVLSYGPCQFPTLGFIVERFWEIQAHPLLAEADLLSCMDK--AGIGTDATMHEHIKKLLDRCYATKDANSRFSPTNLGEALVMGYD--EMGYELWKPYLRAMMEADMKSVSVGTKSKAQVLEGCLQQMKACF
#=GC scorecons                      77757779999999999999989789997693567797479999999999999799989999899996999996688600869999999779999799969999856799699999999979980079696999959975995696596495989579954599696999
#=GC scorecons_70                   ***_***************************__*****_***********************************_***__*_***********************_******************__*********_***_**_***_*__*_***_***___********
#=GC scorecons_80                   _____******************_*****_*___****_****************************_*****__**___*_*******_*****_***_*****__***_*********_***__**_*_****_***_**__*__*__*_***_***___**_*_***
#=GC scorecons_90                   _______****************_****__*_____*___*************_*************_*****__**___*_*******__****_***_*****___**_*********_***___*_*_****_**__**__*__*__*_***__**___**_*_***
//